Macular Degeneration

"Macular Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.

Descriptor ID	D008268
MeSH Number(s)	C11.768.585.439
Concept/Terms	Macular Degeneration Macular Degeneration Degeneration, Macular Degenerations, Macular Macular Degenerations Age-Related Maculopathies Age Related Maculopathies Macular Degeneration, Age-Related Macular Dystrophy Dystrophies, Macular Dystrophy, Macular Macular Dystrophies Maculopathies, Age-Related Maculopathies, Age Related Maculopathy, Age-Related Maculopathy, Age Related Age-Related Macular Degeneration Age Related Macular Degeneration Age-Related Macular Degenerations Degeneration, Age-Related Macular Degenerations, Age-Related Macular Macular Degenerations, Age-Related Age-Related Maculopathy Age Related Maculopathy

Below are MeSH descriptors whose meaning is more general than "Macular Degeneration".

Diseases [C]
Eye Diseases [C11]
Retinal Diseases [C11.768]
Retinal Degeneration [C11.768.585]
Macular Degeneration [C11.768.585.439]

Below are MeSH descriptors whose meaning is related to "Macular Degeneration".

Below are MeSH descriptors whose meaning is more specific than "Macular Degeneration".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Macular Degeneration" by people in this website by year, and whether "Macular Degeneration" was a major or minor topic of these publications.

Bar chart showing 176 publications over 30 distinct years, with a maximum of 13 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	0	2
1997	4	0	4
1999	4	0	4
2000	3	0	3
2001	5	2	7
2002	2	0	2
2003	5	1	6
2004	4	0	4
2005	5	0	5
2006	8	0	8
2007	10	0	10
2008	8	1	9
2009	4	0	4
2010	7	1	8
2011	11	2	13
2012	8	1	9
2013	6	0	6
2014	6	2	8
2015	6	2	8
2016	8	1	9
2017	3	1	4
2018	2	0	2
2019	1	1	2
2020	7	0	7
2021	8	0	8
2022	4	0	4
2023	8	0	8
2024	4	1	5
2025	5	1	6
2026	1	0	1

Below are the most recent publications written about "Macular Degeneration" by people in Profiles.

Cui M, Cheng SY, Liang J, McGowan J, Xu M, Xu G, Luo L, Wu J, Harman CD, Jacobson AL, Kapeller LE, Mayes MA, Namkung S, Sharma T, Leland TB, Zhang F, Yip M, Rossmiller B, Xue T, Chen X, Boonying W, Lotun A, Wang D, Su Q, Xie J, Wei Y, Rothstein AM, Gregory-Ksander MS, Komaromy A, Tian B, Lin H, Punzo C, Tai PWL, Gao G. Modification of the VP1u region boosts transduction of adeno-associated virus vectors for ocular gene therapy. Mol Ther. 2026 May 06; 34(5):2781-2800.

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Khanani AM, Danzig CJ, Heier JS, Jaffe GJ, Kaiser PK, Lally DR, Patel SS, Vajzovic L, Weng CY, Patel H, Clark J, Desai D, Luo D, Henry E, Holz FG. Avacincaptad Pegol for Geographic Atrophy Secondary to Age-Related Macular Degeneration: Two-Year Efficacy and Safety Results from the GATHER2 Phase 3 Trial. Ophthalmology. 2026 04; 133(4):451-465.

View in: PubMed
Seddon JM, De D, Rosner B. Quantifying Effects of Diet and Lifestyle Changes on Progression to Advanced Age Related Macular Degeneration in High Genetic Risk Individuals. Ophthalmology. 2026 03; 133(3):333-349.

View in: PubMed
Lonfat N, Moreno-Leon L, Punzo C, Khanna H. Update on Gene Therapy Clinical Trials for Eye Diseases. Hum Gene Ther. 2025 10; 36(19-20):1287-1300.

View in: PubMed
Park J, Han K, Kim B, Lee K, Jang HR, Yoon JM, Lim DH, Shin DW. Risk of age-related macular degeneration according to the chronic kidney disease and proteinuria in Korea: a 10-year nationwide cohort study. Sci Rep. 2025 Jul 22; 15(1):26595.

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Swan J, Toomey CB, Bergstrand M, Cuello HA, Robie J, Yu H, Yuan Y, Kooner AS, Chen X, Shaughnessy J, Ram S, Varki A, Gagneux P. The Sialome of the Retina, Alteration in Age-Related Macular Degeneration Pathology, and Potential Impacts on Complement Factor H. Invest Ophthalmol Vis Sci. 2025 Jun 02; 66(6):81.

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Cheng SY, Giguere D, Silverstein I, Conza A, Seddon JM, Kim S, Iwata T, Mueller C, Punzo C. Role of alpha-1 antitrypsin in Bruch's membrane integrity. Sci Rep. 2025 Apr 10; 15(1):12223.

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Son KY, Choi YJ, Kim B, Han K, Hwang S, Jung W, Shin DW, Lim DH. Association between Age-Related Macular Degeneration with Visual Disability and Risk of Dementia: A Nationwide Cohort Study. J Am Med Dir Assoc. 2025 02; 26(2):105392.

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Seddon JM, De D, Rosner B. The role of nutritional factors in transitioning between early, mid, and late stages of age-related macular degeneration: prospective longitudinal analysis. Am J Clin Nutr. 2024 12; 120(6):1387-1398.

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Park J, Jung W, Han K, Kim B, Lee SY, Yoon JM, Lim DH, Shin DW. Association between age-related macular degeneration and risk of incident cancer. Br J Ophthalmol. 2024 Aug 22; 108(9):1249-1256.

View in: PubMed

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