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Margaret Ayo Owegi DO

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentNeurology
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
Phone508-856-3008
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentNeurology


    Collapse Biography 
    Collapse education and training
    Indiana State University, Terre Haute, IN, United StatesBSChemistry
    Ball State University, Muncie, IN, United StatesMSChemistry
    Kansas City University of Medicine and Biosciences, Kansas City, MO, United StatesDO

    Collapse Overview 
    Collapse Summary
    Dr. Owegi specializes in neuromuscular disorders in adults. She focuses on motor neuron diseases such as ALS, myasthenia gravis, muscular dystrophies, myopathies and peripheral neuropathies. Owegi graduated from Kansas City University of Medicine and Biosciences. She completed her neurology residency training and neuromuscular disease fellowship at Johns Hopkins Hospital.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Paganoni S, Hendrix S, Dickson SP, Knowlton N, Berry JD, Elliott MA, Maiser S, Karam C, Caress JB, Owegi MA, Quick A, Wymer J, Goutman SA, Heitzman D, Heiman-Patterson TD, Jackson C, Quinn C, Rothstein JD, Kasarskis EJ, Katz J, Jenkins L, Ladha SS, Miller TM, Scelsa SN, Vu TH, Fournier C, Johnson KM, Swenson A, Goyal N, Pattee GL, Babu S, Chase M, Dagostino D, Hall M, Kittle G, Eydinov M, Ostrow J, Pothier L, Randall R, Shefner JM, Sherman AV, Tustison E, Vigneswaran P, Yu H, Cohen J, Klee J, Tanzi R, Gilbert W, Yeramian P, Cudkowicz M. Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial. J Neurol Neurosurg Psychiatry. 2022 May 16. PMID: 35577511.
      Citations:    Fields:    
    2. Cudkowicz ME, Lindborg SR, Goyal NA, Miller RG, Burford MJ, Berry JD, Nicholson KA, Mozaffar T, Katz JS, Jenkins LJ, Baloh RH, Lewis RA, Staff NP, Owegi MA, Berry DA, Gothelf Y, Levy YS, Aricha R, Kern RZ, Windebank AJ, Brown RH. A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis. Muscle Nerve. 2022 03; 65(3):291-302. PMID: 34890069.
      Citations: 5     Fields:    Translation:HumansCellsCTClinical Trials
    3. Quinn C, Mcmillan CT, Owegi MA, Almasy K, Douthwright C, Mckenna-Yasek D, Goyal NA, Berry J, Brown RH. Single breath counting is an effective screening tool for forced vital capacity in ALS. Amyotroph Lateral Scler Frontotemporal Degener. 2021; 22(sup1):5-8. PMID: 34348533.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    4. Paganoni S, Hendrix S, Dickson SP, Knowlton N, Macklin EA, Berry JD, Elliott MA, Maiser S, Karam C, Caress JB, Owegi MA, Quick A, Wymer J, Goutman SA, Heitzman D, Heiman-Patterson TD, Jackson CE, Quinn C, Rothstein JD, Kasarskis EJ, Katz J, Jenkins L, Ladha S, Miller TM, Scelsa SN, Vu TH, Fournier CN, Glass JD, Johnson KM, Swenson A, Goyal NA, Pattee GL, Andres PL, Babu S, Chase M, Dagostino D, Hall M, Kittle G, Eydinov M, McGovern M, Ostrow J, Pothier L, Randall R, Shefner JM, Sherman AV, St Pierre ME, Tustison E, Vigneswaran P, Walker J, Yu H, Chan J, Wittes J, Yu ZF, Cohen J, Klee J, Leslie K, Tanzi RE, Gilbert W, Yeramian PD, Schoenfeld D, Cudkowicz ME. Long-term survival of participants in the CENTAUR trial of sodium phenylbutyrate-taurursodiol in amyotrophic lateral sclerosis. Muscle Nerve. 2021 01; 63(1):31-39. PMID: 33063909.
      Citations: 14     Fields:    Translation:Humans
    5. Paganoni S, Macklin EA, Hendrix S, Berry JD, Elliott MA, Maiser S, Karam C, Caress JB, Owegi MA, Quick A, Wymer J, Goutman SA, Heitzman D, Heiman-Patterson T, Jackson CE, Quinn C, Rothstein JD, Kasarskis EJ, Katz J, Jenkins L, Ladha S, Miller TM, Scelsa SN, Vu TH, Fournier CN, Glass JD, Johnson KM, Swenson A, Goyal NA, Pattee GL, Andres PL, Babu S, Chase M, Dagostino D, Dickson SP, Ellison N, Hall M, Hendrix K, Kittle G, McGovern M, Ostrow J, Pothier L, Randall R, Shefner JM, Sherman AV, Tustison E, Vigneswaran P, Walker J, Yu H, Chan J, Wittes J, Cohen J, Klee J, Leslie K, Tanzi RE, Gilbert W, Yeramian PD, Schoenfeld D, Cudkowicz ME. Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis. N Engl J Med. 2020 09 03; 383(10):919-930. PMID: 32877582.
      Citations: 41     Fields:    Translation:HumansCTClinical Trials
    6. Mueller C, Berry JD, McKenna-Yasek DM, Gernoux G, Owegi MA, Pothier LM, Douthwright CL, Gelevski D, Luppino SD, Blackwood M, Wightman NS, Oakley DH, Frosch MP, Flotte TR, Cudkowicz ME, Brown RH. SOD1 Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS. N Engl J Med. 2020 07 09; 383(2):151-158. PMID: 32640133.
      Citations: 42     Fields:    Translation:HumansCells
    7. Berry JD, Cudkowicz ME, Windebank AJ, Staff NP, Owegi M, Nicholson K, McKenna-Yasek D, Levy YS, Abramov N, Kaspi H, Mehra M, Aricha R, Gothelf Y, Brown RH. NurOwn, phase 2, randomized, clinical trial in patients with ALS: Safety, clinical, and biomarker results. Neurology. 2019 12 10; 93(24):e2294-e2305. PMID: 31740545.
      Citations: 29     Fields:    Translation:HumansCTClinical Trials
    8. Cammack AJ, Atassi N, Hyman T, van den Berg LH, Harms M, Baloh RH, Brown RH, van Es MA, Veldink JH, de Vries BS, Rothstein JD, Drain C, Jockel-Balsarotti J, Malcolm A, Boodram S, Salter A, Wightman N, Yu H, Sherman AV, Esparza TJ, McKenna-Yasek D, Owegi MA, Douthwright C, McCampbell A, Ferguson T, Cruchaga C, Cudkowicz M, Miller TM. Prospective natural history study of C9orf72 ALS clinical characteristics and biomarkers. Neurology. 2019 10 22; 93(17):e1605-e1617. PMID: 31578300.
      Citations: 9     Fields:    Translation:HumansCells
    9. Ghasemi M, Kaddouh F, Deb A, Owegi MA. Delayed-onset MRI findings in acute chorea related to anoxic brain injury. Clin Imaging. 2018 Mar - Apr; 48:22-25. PMID: 29028509.
      Citations:    Fields:    Translation:Humans
    10. Vernon HJ, Bytyci Telegrafi A, Batista D, Owegi M, Leigh R. 6p25 microdeletion: white matter abnormalities in an adult patient. Am J Med Genet A. 2013 Jul; 161A(7):1686-9. PMID: 23686687.
      Citations: 5     Fields:    Translation:HumansCells
    11. Owegi MA, Pappas DL, Finch MW, Bilbo SA, Resendiz CA, Jacquemin LJ, Warrier A, Trombley JD, McCulloch KM, Margalef KL, Mertz MJ, Storms JM, Damin CA, Parra KJ. Identification of a domain in the V0 subunit d that is critical for coupling of the yeast vacuolar proton-translocating ATPase. J Biol Chem. 2006 Oct 06; 281(40):30001-14. PMID: 16891312.
      Citations: 21     Fields:    Translation:Cells
    12. Owegi MA, Carenbauer AL, Wick NM, Brown JF, Terhune KL, Bilbo SA, Weaver RS, Shircliff R, Newcomb N, Parra-Belky KJ. Mutational analysis of the stator subunit E of the yeast V-ATPase. J Biol Chem. 2005 May 06; 280(18):18393-402. PMID: 15718227.
      Citations: 17     Fields:    Translation:AnimalsCells
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