"alpha-Globins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Members of the alpha-globin family. In humans, they are encoded in a gene cluster on CHROMOSOME 16. They include zeta-globin and alpha-globin. There are also pseudogenes of zeta (theta-zeta) and alpha (theta-alpha) in the cluster. Adult HEMOGLOBIN is comprised of 2 alpha-globin chains and 2 beta-globin chains.
| Descriptor ID |
D055542
|
| MeSH Number(s) |
D12.776.124.400.434.320 D12.776.422.316.762.403.320
|
| Concept/Terms |
alpha-1 Globin- alpha-1 Globin
- Globin, alpha-1
- alpha 1 Globin
- alpha 1-globin
- 1-globin, alpha
|
Below are MeSH descriptors whose meaning is more general than "alpha-Globins".
Below are MeSH descriptors whose meaning is more specific than "alpha-Globins".
This graph shows the total number of publications written about "alpha-Globins" by people in this website by year, and whether "alpha-Globins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "alpha-Globins" by people in Profiles.
-
Ulianov SV, Galitsyna AA, Flyamer IM, Golov AK, Khrameeva EE, Imakaev MV, Abdennur NA, Gelfand MS, Gavrilov AA, Razin SV. Activation of the alpha-globin gene expression correlates with dramatic upregulation of nearby non-globin genes and changes in local and large-scale chromatin spatial structure. Epigenetics Chromatin. 2017 07 11; 10(1):35.
-
Ba? D, Sanyal A, Lajoie BR, Capriotti E, Byron M, Lawrence JB, Dekker J, Marti-Renom MA. The three-dimensional folding of the a-globin gene domain reveals formation of chromatin globules. Nat Struct Mol Biol. 2011 Jan; 18(1):107-14.
-
Mahajan MC, Karmakar S, Newburger PE, Krause DS, Weissman SM. Dynamics of alpha-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34(+) cells in culture. Exp Hematol. 2009 Oct; 37(10):1143-1156.e3.
-
Tezel TH, Geng L, Lato EB, Schaal S, Liu Y, Dean D, Klein JB, Kaplan HJ. Synthesis and secretion of hemoglobin by retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2009 Apr; 50(4):1911-9.