Sciatic Nerve
"Sciatic Nerve" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.
Descriptor ID |
D012584
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MeSH Number(s) |
A08.800.800.720.450.760
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Concept/Terms |
Sciatic Nerve- Sciatic Nerve
- Nerve, Sciatic
- Nerves, Sciatic
- Sciatic Nerves
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Below are MeSH descriptors whose meaning is more general than "Sciatic Nerve".
Below are MeSH descriptors whose meaning is more specific than "Sciatic Nerve".
This graph shows the total number of publications written about "Sciatic Nerve" by people in this website by year, and whether "Sciatic Nerve" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1986 | 0 | 1 | 1 | 1987 | 0 | 1 | 1 | 1989 | 0 | 1 | 1 | 1993 | 0 | 1 | 1 | 1994 | 0 | 1 | 1 | 1997 | 0 | 1 | 1 | 2004 | 0 | 1 | 1 | 2005 | 1 | 0 | 1 | 2006 | 0 | 1 | 1 | 2008 | 1 | 1 | 2 | 2009 | 0 | 1 | 1 | 2010 | 0 | 1 | 1 | 2011 | 0 | 2 | 2 | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sciatic Nerve" by people in Profiles.
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Osterloh JM, Yang J, Rooney TM, Fox AN, Adalbert R, Powell EH, Sheehan AE, Avery MA, Hackett R, Logan MA, MacDonald JM, Ziegenfuss JS, Milde S, Hou YJ, Nathan C, Ding A, Brown RH, Conforti L, Coleman M, Tessier-Lavigne M, Züchner S, Freeman MR. dSarm/Sarm1 is required for activation of an injury-induced axon death pathway. Science. 2012 Jul 27; 337(6093):481-4.
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Susuki K, Yuki N, Schafer DP, Hirata K, Zhang G, Funakoshi K, Rasband MN. Dysfunction of nodes of Ranvier: a mechanism for anti-ganglioside antibody-mediated neuropathies. Exp Neurol. 2012 Jan; 233(1):534-42.
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Garofalo K, Penno A, Schmidt BP, Lee HJ, Frosch MP, von Eckardstein A, Brown RH, Hornemann T, Eichler FS. Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1. J Clin Invest. 2011 Dec; 121(12):4735-45.
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Su JH, Chen YF, Tang JR, Wu L, Zhang P, Yu LB, Niu Q, Xiao H. Protective effects of the calcium-channel blocker flunarizine on crush injury of sciatic nerves in a rat model. Neurol India. 2010 Jul-Aug; 58(4):530-6.
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O'Neill AC, Randolph MA, Bujold KE, Kochevar IE, Redmond RW, Winograd JM. Preparation and integration of human amnion nerve conduits using a light-activated technique. Plast Reconstr Surg. 2009 Aug; 124(2):428-37.
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O'Neill AC, Randolph MA, Bujold KE, Kochevar IE, Redmond RW, Winograd JM. Photochemical sealing improves outcome following peripheral neurorrhaphy. J Surg Res. 2009 Jan; 151(1):33-9.
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Mills C, Makwana M, Wallace A, Benn S, Schmidt H, Tegeder I, Costigan M, Brown RH, Raivich G, Woolf CJ. Ro5-4864 promotes neonatal motor neuron survival and nerve regeneration in adult rats. Eur J Neurosci. 2008 Feb; 27(4):937-46.
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Milligan ED, Sloane EM, Langer SJ, Hughes TS, Jekich BM, Frank MG, Mahoney JH, Levkoff LH, Maier SF, Cruz PE, Flotte TR, Johnson KW, Mahoney MM, Chavez RA, Leinwand LA, Watkins LR. Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain. Pain. 2006 Dec 15; 126(1-3):294-308.
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Milligan ED, Sloane EM, Langer SJ, Cruz PE, Chacur M, Spataro L, Wieseler-Frank J, Hammack SE, Maier SF, Flotte TR, Forsayeth JR, Leinwand LA, Chavez R, Watkins LR. Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10. Mol Pain. 2005 Feb 25; 1:9.
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Keramaris E, Vanderluit JL, Bahadori M, Mousavi K, Davis RJ, Flavell R, Slack RS, Park DS. c-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation. J Biol Chem. 2005 Jan 14; 280(2):1132-41.
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