 Phosphotyrosine
"Phosphotyrosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis.
| Descriptor ID |
D019000
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| MeSH Number(s) |
D12.125.072.050.875.750 D12.125.740.740
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phosphotyrosine".
Below are MeSH descriptors whose meaning is more specific than "Phosphotyrosine".
This graph shows the total number of publications written about "Phosphotyrosine" by people in this website by year, and whether "Phosphotyrosine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 1 | 1 | | 1994 | 0 | 2 | 2 | | 1996 | 2 | 0 | 2 | | 1999 | 1 | 1 | 2 | | 2002 | 0 | 3 | 3 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphotyrosine" by people in Profiles.
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Tan SX, Ng Y, Burchfield JG, Ramm G, Lambright DG, Stöckli J, James DE. The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes. Mol Cell Biol. 2012 Dec; 32(24):4946-59.
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Hagan GN, Lin Y, Magnuson MA, Avruch J, Czech MP. A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes. Mol Cell Biol. 2008 Jul; 28(13):4215-26.
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Kaleem A, Ahmad I, Hoessli DC, Walker-Nasir E, Saleem M, Shakoori AR. Epidermal growth factor receptors: function modulation by phosphorylation and glycosylation interplay. Mol Biol Rep. 2009 Apr; 36(4):631-9.
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Sheth P, Seth A, Atkinson KJ, Gheyi T, Kale G, Giorgianni F, Desiderio DM, Li C, Naren A, Rao R. Acetaldehyde dissociates the PTP1B-E-cadherin-beta-catenin complex in Caco-2 cell monolayers by a phosphorylation-dependent mechanism. Biochem J. 2007 Mar 1; 402(2):291-300.
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DiNitto JP, Lambright DG. Membrane and juxtamembrane targeting by PH and PTB domains. Biochim Biophys Acta. 2006 Aug; 1761(8):850-67.
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Kim HJ, Vosseler CA, Weber PC, Erl W. Docosahexaenoic acid induces apoptosis in proliferating human endothelial cells. J Cell Physiol. 2005 Sep; 204(3):881-8.
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Zabolotny JM, Haj FG, Kim YB, Kim HJ, Shulman GI, Kim JK, Neel BG, Kahn BB. Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action. J Biol Chem. 2004 Jun 4; 279(23):24844-51.
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Steiler TL, Galuska D, Leng Y, Chibalin AV, Gilbert M, Zierath JR. Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats. Endocrinology. 2003 Dec; 144(12):5259-67.
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Yu C, Chen Y, Cline GW, Zhang D, Zong H, Wang Y, Bergeron R, Kim JK, Cushman SW, Cooney GJ, Atcheson B, White MF, Kraegen EW, Shulman GI. Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem. 2002 Dec 27; 277(52):50230-6.
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Bei Y, Hogan J, Berkowitz LA, Soto M, Rocheleau CE, Pang KM, Collins J, Mello CC. SRC-1 and Wnt signaling act together to specify endoderm and to control cleavage orientation in early C. elegans embryos. Dev Cell. 2002 Jul; 3(1):113-25.
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