Lymphocyte Culture Test, Mixed

"Lymphocyte Culture Test, Mixed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.

Descriptor ID	D007959
MeSH Number(s)	E01.370.225.812.385.475 E05.200.812.385.475 E05.478.594.385.429
Concept/Terms	Lymphocyte Culture Test, Mixed Lymphocyte Culture Test, Mixed Leukocyte Culture Test, Mixed Mixed Lymphocyte Reaction Lymphocyte Reaction, Mixed Lymphocyte Reactions, Mixed Mixed Lymphocyte Reactions Mixed Leukocyte Reaction Leukocyte Reaction, Mixed Leukocyte Reactions, Mixed Mixed Leukocyte Reactions Mixed Leukocyte Culture Test Mixed Lymphocyte Culture Test

Below are MeSH descriptors whose meaning is more general than "Lymphocyte Culture Test, Mixed".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Diagnosis [E01]
Diagnostic Techniques and Procedures [E01.370]
Clinical Laboratory Techniques [E01.370.225]
Immunologic Tests [E01.370.225.812]
Histocompatibility Testing [E01.370.225.812.385]
Lymphocyte Culture Test, Mixed [E01.370.225.812.385.475]
Investigative Techniques [E05]
Clinical Laboratory Techniques [E05.200]
Immunologic Tests [E05.200.812]
Histocompatibility Testing [E05.200.812.385]
Lymphocyte Culture Test, Mixed [E05.200.812.385.475]
Immunologic Techniques [E05.478]
Immunologic Tests [E05.478.594]
Histocompatibility Testing [E05.478.594.385]
Lymphocyte Culture Test, Mixed [E05.478.594.385.429]

Below are MeSH descriptors whose meaning is related to "Lymphocyte Culture Test, Mixed".

Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Culture Test, Mixed".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Lymphocyte Culture Test, Mixed" by people in this website by year, and whether "Lymphocyte Culture Test, Mixed" was a major or minor topic of these publications.

Bar chart showing 17 publications over 13 distinct years, with a maximum of 3 publications in 2001

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1995	1	1
1999	2	2
2000	1	1
2001	3	3
2002	1	1
2003	2	2
2004	1	1
2005	1	1
2007	1	1
2008	1	1
2009	1	1
2012	1	1
2015	1	1

Below are the most recent publications written about "Lymphocyte Culture Test, Mixed" by people in Profiles.

Meng L, Bai Z, He S, Mochizuki K, Liu Y, Purushe J, Sun H, Wang J, Yagita H, Mineishi S, Fung H, Yanik GA, Caricchio R, Fan X, Crisalli LM, Hexner EO, Reshef R, Zhang Y, Zhang Y. The Notch Ligand DLL4 Defines a Capability of Human Dendritic Cells in Regulating Th1 and Th17 Differentiation. J Immunol. 2016 Feb 01; 196(3):1070-80.

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Dolganiuc A, Kodys K, Marshall C, Saha B, Zhang S, Bala S, Szabo G. Type III interferons, IL-28 and IL-29, are increased in chronic HCV infection and induce myeloid dendritic cell-mediated FoxP3+ regulatory T cells. PLoS One. 2012; 7(10):e44915.

View in: PubMed
King MA, Covassin L, Brehm MA, Racki W, Pearson T, Leif J, Laning J, Fodor W, Foreman O, Burzenski L, Chase TH, Gott B, Rossini AA, Bortell R, Shultz LD, Greiner DL. Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex. Clin Exp Immunol. 2009 Jul; 157(1):104-18.

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Szabo G, Mandrekar P. Human monocytes, macrophages, and dendritic cells: alcohol treatment methods. Methods Mol Biol. 2008; 447:113-24.

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Huurman VA, Unger WW, Koeleman BP, Oaks MK, Chandraker AK, Terpstra OT, Roep BO. Differential inhibition of autoreactive memory- and alloreactive naive T cell responses by soluble cytotoxic T lymphocyte antigen 4 (sCTLA4), CTLA4Ig and LEA29Y. Clin Exp Immunol. 2007 Dec; 150(3):487-93.

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Cho PS, Messina DJ, Hirsh EL, Chi N, Goldman SN, Lo DP, Harris IR, Popma SH, Sachs DH, Huang CA. Immunogenicity of umbilical cord tissue derived cells. Blood. 2008 Jan 01; 111(1):430-8.

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Azzoni L, Chehimi J, Zhou L, Foulkes AS, June R, Maino VC, Landay A, Rinaldo C, Jacobson LP, Montaner LJ. Early and delayed benefits of HIV-1 suppression: timeline of recovery of innate immunity effector cells. AIDS. 2007 Jan 30; 21(3):293-305.

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Chandraker A, Huurman V, Hallett K, Yuan X, Tector AJ, Park CH, Lu E, Zavazava N, Oaks M. CTLA-4 is important in maintaining long-term survival of cardiac allografts. Transplantation. 2005 Apr 27; 79(8):897-903.

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Moseman EA, Liang X, Dawson AJ, Panoskaltsis-Mortari A, Krieg AM, Liu YJ, Blazar BR, Chen W. Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells. J Immunol. 2004 Oct 01; 173(7):4433-42.

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Salama AD, Yuan X, Nayer A, Chandraker A, Inobe M, Uede T, Sayegh MH. Interaction between ICOS-B7RP1 and B7-CD28 costimulatory pathways in alloimmune responses in vivo. Am J Transplant. 2003 Apr; 3(4):390-5.

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