"Histamine H2 Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
| Descriptor ID |
D006635
|
| MeSH Number(s) |
D27.505.519.625.375.425.425 D27.505.696.577.375.425.425
|
| Concept/Terms |
Histamine H2 Antagonists- Histamine H2 Antagonists
- Receptor Blockaders, H2
- Blockaders, Histamine H2 Receptor
- Histamine H2 Receptor Blockaders
- Histamine H2 Blockers
- Blockers, Histamine H2
- H2 Blockers, Histamine
- Receptor Antagonists, Histamine H2
- Histamine H2 Receptor Antagonists
- Antagonists, Histamine H2
- H2 Antagonists, Histamine
- H2 Receptor Blockaders
- Blockaders, H2 Receptor
- Antihistaminics, H2
- H2 Antihistaminics
|
Below are MeSH descriptors whose meaning is more general than "Histamine H2 Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Histamine H2 Antagonists".
This graph shows the total number of publications written about "Histamine H2 Antagonists" by people in this website by year, and whether "Histamine H2 Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Histamine H2 Antagonists" by people in Profiles.
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Dinesh D, Lee JS, Scott TM, Tucker KL, Palacios N. Association between Acid-Lowering Agents, Metformin, and Vitamin B12 among Boston-Area Puerto Ricans. J Nutr. 2023 08; 153(8):2380-2388.
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Marchina S, Doros G, Modak J, Helenius J, Aycock DM, Kumar S. Acid-suppressive medications and risk of pneumonia in acute stroke patients: A systematic review and meta-analysis. J Neurol Sci. 2019 May 15; 400:122-128.
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Lilly CM, Aljawadi M, Badawi O, Onukwugha E, Tom SE, Magder LS, Harris I. Comparative Effectiveness of Proton Pump?Inhibitors vs Histamine Type 2 Receptor Blockers for Preventing Clinically Important Gastrointestinal Bleeding During?Intensive?Care: A Population-Based Study. Chest. 2018 09; 154(3):557-566.
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Freedberg DE, Lamous?-Smith ES, Lightdale JR, Jin Z, Yang YX, Abrams JA. Use of Acid Suppression Medication is Associated With Risk for C. difficile Infection in Infants and Children: A Population-based Study. Clin Infect Dis. 2015 Sep 15; 61(6):912-7.
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Butler JR, Rogers T, Eckart G, Martens GR, Ceppa EP, House MG, Nakeeb A, Schmidt CM, Zyromski NJ. Is antisecretory therapy after pancreatoduodenectomy necessary? Meta-analysis and contemporary practices of pancreatic surgeons. J Gastrointest Surg. 2015 Apr; 19(4):604-12.
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Papagerakis S, Bellile E, Peterson LA, Pliakas M, Balaskas K, Selman S, Hanauer D, Taylor JM, Duffy S, Wolf G. Proton pump inhibitors and histamine 2 blockers are associated with improved overall survival in patients with head and neck squamous carcinoma. Cancer Prev Res (Phila). 2014 Dec; 7(12):1258-69.
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Bajaj JS, Ratliff SM, Heuman DM, Lapane KL. Proton pump inhibitors are associated with a high rate of serious infections in veterans with decompensated cirrhosis. Aliment Pharmacol Ther. 2012 Nov; 36(9):866-74.
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Kwok CS, Arthur AK, Anibueze CI, Singh S, Cavallazzi R, Loke YK. Risk of Clostridium difficile infection with acid suppressing drugs and antibiotics: meta-analysis. Am J Gastroenterol. 2012 Jul; 107(7):1011-9.
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Hussain S, Stefan M, Visintainer P, Rothberg M. Why do physicians prescribe stress ulcer prophylaxis to general medicine patients? South Med J. 2010 Nov; 103(11):1103-10.
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Takaishi S, Cui G, Frederick DM, Carlson JE, Houghton J, Varro A, Dockray GJ, Ge Z, Whary MT, Rogers AB, Fox JG, Wang TC. Synergistic inhibitory effects of gastrin and histamine receptor antagonists on Helicobacter-induced gastric cancer. Gastroenterology. 2005 Jun; 128(7):1965-83.