"Histamine H1 Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.
| Descriptor ID |
D006634
|
| MeSH Number(s) |
D27.505.519.625.375.425.400 D27.505.696.577.375.425.400
|
| Concept/Terms |
Histamine H1 Antagonists- Histamine H1 Antagonists
- H1 Antagonists, Histamine
- Antagonists, Histamine H1 Receptor
- Antihistaminics, H1
- H1 Antihistaminics
- Receptor Blockaders, H1
- H1 Receptor Blockaders
- Histamine H1 Blockers
- Histamine H1 Receptor Antagonists
- Histamine H1 Receptor Blockaders
- Antagonists, Histamine H1
- Blockaders, Histamine H1 Receptor
Antihistamines, Classical- Antihistamines, Classical
- Classical Antihistamines
- Antihistaminics, Classical
- Classical Antihistaminics
- First Generation H1 Antagonists
- Antihistamines, Sedating
- Sedating Antihistamines
|
Below are MeSH descriptors whose meaning is more general than "Histamine H1 Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Histamine H1 Antagonists".
This graph shows the total number of publications written about "Histamine H1 Antagonists" by people in this website by year, and whether "Histamine H1 Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Histamine H1 Antagonists" by people in Profiles.
-
Hujoel PP, Cunha-Cruz J, Maupome G, Saver B. Long-term use of medications and destructive periodontal disease. J Periodontol. 2008 Aug; 79(8):1330-8.
-
Morin AK, Jarvis CI, Lynch AM. Therapeutic options for sleep-maintenance and sleep-onset insomnia. Pharmacotherapy. 2007 Jan; 27(1):89-110.
-
Madison JM, Irwin RS. Pharmacotherapy of chronic cough in adults. Expert Opin Pharmacother. 2003 Jul; 4(7):1039-48.
-
Bird SB, Gaspari RJ, Dickson EW. Early death due to severe organophosphate poisoning is a centrally mediated process. Acad Emerg Med. 2003 Apr; 10(4):295-8.
-
Bird SB, Gaspari RJ, Lee WJ, Dickson EW. Diphenhydramine as a protective agent in a rat model of acute, lethal organophosphate poisoning. Acad Emerg Med. 2002 Dec; 9(12):1369-72.
-
Mills JH, Matthews LJ, Lee FS, Dubno JR, Schulte BA, Weber PC. Gender-specific effects of drugs on hearing levels of older persons. Ann N Y Acad Sci. 1999 Nov 28; 884:381-8.
-
Garbus SB, Moulton BW, Meltzer EO, Reich PR, Weinreb LF, Friedman JA, Orland BI. Considerations in pharmaceutical conversion: focus on antihistamines. Am J Manag Care. 1997 Apr; 3(4):617-30.
-
Sreebny LM, Valdini A, Yu A. Xerostomia. Part II: Relationship to nonoral symptoms, drugs, and diseases. Oral Surg Oral Med Oral Pathol. 1989 Oct; 68(4):419-27.
-
Cockerham LG, Pautler EL, Carraway RE, Cochrane DE, Hampton JD. Effect of disodium cromoglycate (DSCG) and antihistamines on postirradiation cerebral blood flow and plasma levels of histamine and neurotensin. Fundam Appl Toxicol. 1988 Feb; 10(2):233-42.