Ghrelin

"Ghrelin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.

Descriptor ID	D054439
MeSH Number(s)	D06.472.699.301 D12.644.548.322
Concept/Terms	Ghrelin Ghrelin GHRL Protein GHRL Protein Ppghrelin Ghrelin-Obestatin Preprohormone Ghrelin Obestatin Preprohormone Motilin-Related Peptide Precursor Motilin Related Peptide Precursor Peptide Precursor, Motilin-Related Precursor, Motilin-Related Peptide PpMTLRP Ghrelin Precursor Precursor, Ghrelin Obestatin Obestatin Appetite-Regulating Hormone Appetite-Regulating Hormone Appetite Regulating Hormone Motilin-Related Peptide Motilin Related Peptide Gastric MLTRP

Below are MeSH descriptors whose meaning is more general than "Ghrelin".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Ghrelin [D06.472.699.301]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Peptide Hormones [D12.644.548]
Ghrelin [D12.644.548.322]

Below are MeSH descriptors whose meaning is more specific than "Ghrelin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ghrelin" by people in this website by year, and whether "Ghrelin" was a major or minor topic of these publications.

Bar chart showing 17 publications over 10 distinct years, with a maximum of 4 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2006	0	1	1
2007	1	2	3
2008	1	1	2
2011	2	0	2
2012	0	1	1
2013	3	1	4
2016	0	1	1
2023	0	1	1
2024	1	0	1

Below are the most recent publications written about "Ghrelin" by people in Profiles.

Mahalingam S, Bellamkonda R, Kharbanda KK, Arumugam MK, Kumar V, Casey CA, Leggio L, Rasineni K. Role of ghrelin hormone in the development of alcohol-associated liver disease. Biomed Pharmacother. 2024 May; 174:116595.

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Lim JJ, Liu Y, Lu LW, Sequeira IR, Poppitt SD. No Evidence That Circulating GLP-1 or PYY Are Associated with Increased Satiety during Low Energy Diet-Induced Weight Loss: Modelling Biomarkers of Appetite. Nutrients. 2023 May 20; 15(10).

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Hofmann T, Elbelt U, Haas V, Ahnis A, Klapp BF, Rose M, Stengel A. Plasma kisspeptin and ghrelin levels are independently correlated with physical activity in patients with anorexia nervosa. Appetite. 2017 01 01; 108:141-150.

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Barja-Fernandez S, Folgueira C, Castelao C, Leis R, Crujeiras AB, Casanueva FF, Seoane LM. Regulation of Growth Hormone by the Splanchnic Area. Prog Mol Biol Transl Sci. 2016; 138:41-60.

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Engster KM, Wismar J, Kroczek AL, Teuffel P, Nolte S, Rose M, Stengel A, Kobelt P. The dopamine antagonist flupentixol does not alter ghrelin-induced food intake in rats. Neuropeptides. 2015 Oct; 53:19-27.

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Senin LL, Al-Massadi O, Folgueira C, Castelao C, Pardo M, Barja-Fernandez S, Roca-Rivada A, Amil M, Crujeiras AB, Garcia-Caballero T, Gabellieri E, Leis R, Dieguez C, Pagotto U, Casanueva FF, Seoane LM. The gastric CB1 receptor modulates ghrelin production through the mTOR pathway to regulate food intake. PLoS One. 2013; 8(11):e80339.

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Yu Z, Lowndes J, Rippe J. High-fructose corn syrup and sucrose have equivalent effects on energy-regulating hormones at normal human consumption levels. Nutr Res. 2013 Dec; 33(12):1043-52.

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Romero-Pic? A, Novelle MG, Folgueira C, L?pez M, Nogueiras R, Di?guez C. Central manipulation of dopamine receptors attenuates the orexigenic action of ghrelin. Psychopharmacology (Berl). 2013 Sep; 229(2):275-83.

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Romero-Pic? A, V?zquez MJ, Gonz?lez-Touceda D, Folgueira C, Skibicka KP, Alvarez-Crespo M, Van Gestel MA, Vel?squez DA, Schwarzer C, Herzog H, L?pez M, Adan RA, Dickson SL, Di?guez C, Nogueiras R. Hypothalamic ?-opioid receptor modulates the orexigenic effect of ghrelin. Neuropsychopharmacology. 2013 Jun; 38(7):1296-307.

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Granados K, Stephens BR, Malin SK, Zderic TW, Hamilton MT, Braun B. Appetite regulation in response to sitting and energy imbalance. Appl Physiol Nutr Metab. 2012 Apr; 37(2):323-33.

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