"Ghrelin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.
| Descriptor ID |
D054439
|
| MeSH Number(s) |
D06.472.699.301 D12.644.548.322
|
| Concept/Terms |
GHRL Protein- GHRL Protein
- Ppghrelin
- Ghrelin-Obestatin Preprohormone
- Ghrelin Obestatin Preprohormone
- Motilin-Related Peptide Precursor
- Motilin Related Peptide Precursor
- Peptide Precursor, Motilin-Related
- Precursor, Motilin-Related Peptide
- PpMTLRP
- Ghrelin Precursor
- Precursor, Ghrelin
Appetite-Regulating Hormone- Appetite-Regulating Hormone
- Appetite Regulating Hormone
- Motilin-Related Peptide
- Motilin Related Peptide
- Gastric MLTRP
|
Below are MeSH descriptors whose meaning is more general than "Ghrelin".
Below are MeSH descriptors whose meaning is more specific than "Ghrelin".
This graph shows the total number of publications written about "Ghrelin" by people in this website by year, and whether "Ghrelin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ghrelin" by people in Profiles.
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Mahalingam S, Bellamkonda R, Kharbanda KK, Arumugam MK, Kumar V, Casey CA, Leggio L, Rasineni K. Role of ghrelin hormone in the development of alcohol-associated liver disease. Biomed Pharmacother. 2024 May; 174:116595.
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Hofmann T, Elbelt U, Haas V, Ahnis A, Klapp BF, Rose M, Stengel A. Plasma kisspeptin and ghrelin levels are independently correlated with physical activity in patients with anorexia nervosa. Appetite. 2017 01 01; 108:141-150.
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Engster KM, Wismar J, Kroczek AL, Teuffel P, Nolte S, Rose M, Stengel A, Kobelt P. The dopamine antagonist flupentixol does not alter ghrelin-induced food intake in rats. Neuropeptides. 2015 Oct; 53:19-27.
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Yu Z, Lowndes J, Rippe J. High-fructose corn syrup and sucrose have equivalent effects on energy-regulating hormones at normal human consumption levels. Nutr Res. 2013 Dec; 33(12):1043-52.
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Must A, Parisi SM. Sedentary behavior and sleep: paradoxical effects in association with childhood obesity. Int J Obes (Lond). 2009 Apr; 33 Suppl 1:S82-6.
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Ingelsson E, Larson MG, Yin X, Wang TJ, Meigs JB, Lipinska I, Benjamin EJ, Keaney JF, Vasan RS. Circulating ghrelin, leptin, and soluble leptin receptor concentrations and cardiometabolic risk factors in a community-based sample. J Clin Endocrinol Metab. 2008 Aug; 93(8):3149-57.
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Wang Y, Ray SK, Hinds PW, Leiter AB. The retinoblastoma protein, RB, is required for gastrointestinal endocrine cells to exit the cell cycle, but not for hormone expression. Dev Biol. 2007 Nov 15; 311(2):478-86.
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Melanson KJ, Zukley L, Lowndes J, Nguyen V, Angelopoulos TJ, Rippe JM. Effects of high-fructose corn syrup and sucrose consumption on circulating glucose, insulin, leptin, and ghrelin and on appetite in normal-weight women. Nutrition. 2007 Feb; 23(2):103-12.
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Adams SH, Won WB, Schonhoff SE, Leiter AB, Paterniti JR. Effects of peptide YY[3-36] on short-term food intake in mice are not affected by prevailing plasma ghrelin levels. Endocrinology. 2004 Nov; 145(11):4967-75.