 Estradiol
"Estradiol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. In humans, it is produced primarily by the cyclic ovaries and the PLACENTA. It is also produced by the adipose tissue of men and postmenopausal women. The 17-alpha-isomer of estradiol binds weakly to estrogen receptors (RECEPTORS, ESTROGEN) and exhibits little estrogenic activity in estrogen-responsive tissues. Various isomers can be synthesized.
| Descriptor ID |
D004958
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| MeSH Number(s) |
D04.808.365.415.248 D06.472.334.851.437.500
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| Concept/Terms |
Estradiol- Estradiol
- 17 beta-Oestradiol
- 17 beta Oestradiol
- Estradiol-17beta
- Estradiol 17beta
- Oestradiol
- 17 beta-Estradiol
- 17 beta Estradiol
- Estradiol-17 beta
- Estradiol 17 beta
Ovocyclin- Ovocyclin
- Orion Brand of Estradiol
- Estradiol Orion Brand
Vivelle- Vivelle
- Novartis Pharmaceuticals Brand of Estradiol
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Below are MeSH descriptors whose meaning is more general than "Estradiol".
Below are MeSH descriptors whose meaning is more specific than "Estradiol".
This graph shows the total number of publications written about "Estradiol" by people in this website by year, and whether "Estradiol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 3 | 3 | | 1981 | 1 | 1 | 2 | | 1982 | 2 | 4 | 6 | | 1983 | 2 | 1 | 3 | | 1984 | 2 | 4 | 6 | | 1985 | 0 | 4 | 4 | | 1986 | 0 | 4 | 4 | | 1987 | 2 | 3 | 5 | | 1988 | 4 | 1 | 5 | | 1989 | 5 | 1 | 6 | | 1990 | 0 | 4 | 4 | | 1991 | 4 | 1 | 5 | | 1992 | 4 | 3 | 7 | | 1993 | 3 | 4 | 7 | | 1994 | 4 | 1 | 5 | | 1995 | 2 | 1 | 3 | | 1996 | 1 | 5 | 6 | | 1997 | 1 | 3 | 4 | | 1998 | 1 | 2 | 3 | | 1999 | 0 | 2 | 2 | | 2000 | 1 | 4 | 5 | | 2001 | 2 | 1 | 3 | | 2002 | 4 | 4 | 8 | | 2003 | 5 | 3 | 8 | | 2004 | 1 | 10 | 11 | | 2005 | 1 | 2 | 3 | | 2006 | 1 | 4 | 5 | | 2007 | 3 | 3 | 6 | | 2008 | 1 | 7 | 8 | | 2009 | 4 | 3 | 7 | | 2010 | 9 | 2 | 11 | | 2011 | 0 | 3 | 3 | | 2012 | 7 | 2 | 9 | | 2013 | 0 | 2 | 2 | | 2014 | 2 | 4 | 6 | | 2015 | 2 | 2 | 4 | | 2016 | 1 | 1 | 2 |
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Below are the most recent publications written about "Estradiol" by people in Profiles.
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Keaney JF, Solomon CG. Postmenopausal Hormone Therapy and Atherosclerosis--Time Is of the Essence. N Engl J Med. 2016 Mar 31; 374(13):1279-80.
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Zsakai A, Karkus Z, Utczas K, Biri B, Sievert LL, Bodzsar EB. Body fatness and endogenous sex hormones in the menopausal transition. Maturitas. 2016 May; 87:18-26.
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Domínguez-Ordóñez R, García-Juárez M, Lima-Hernández FJ, Gómora-Arrati P, Blaustein JD, González-Flores O. Sexual receptivity facilitated by unesterified estradiol: Dependence on estrogen and progestin receptors and priming dose of estradiol benzoate. Behav Neurosci. 2015 Dec; 129(6):777-88.
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Vanden Brink H, Robertson DM, Lim H, Lee C, Chizen D, Harris G, Hale G, Burger H, Baerwald A. Associations Between Antral Ovarian Follicle Dynamics and Hormone Production Throughout the Menstrual Cycle as Women Age. J Clin Endocrinol Metab. 2015 Dec; 100(12):4553-62.
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Del Pino Sans J, Krishnan S, Aggison LK, Adams HL, Shrikant MM, López-Giráldez F, Petersen SL. Microarray analysis of neonatal rat anteroventral periventricular transcriptomes identifies the proapoptotic Cugbp2 gene as sex-specific and regulated by estradiol. Neuroscience. 2015 Sep 10; 303:312-22.
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Zhu J, Jiang L, Liu Y, Qian W, Liu J, Zhou J, Gao R, Xiao H, Wang J. MAPK and NF-?B pathways are involved in bisphenol A-induced TNF-a and IL-6 production in BV2 microglial cells. Inflammation. 2015 Apr; 38(2):637-48.
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Navarro VM, Bosch MA, León S, Simavli S, True C, Pinilla L, Carroll RS, Seminara SB, Tena-Sempere M, Rønnekleiv OK, Kaiser UB. The integrated hypothalamic tachykinin-kisspeptin system as a central coordinator for reproduction. Endocrinology. 2015 Feb; 156(2):627-37.
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Carroll KJ, Esain V, Garnaas MK, Cortes M, Dovey MC, Nissim S, Frechette GM, Liu SY, Kwan W, Cutting CC, Harris JM, Gorelick DA, Halpern ME, Lawson ND, Goessling W, North TE. Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche. Dev Cell. 2014 May 27; 29(4):437-53.
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Lynch KE, Mumford SL, Schliep KC, Whitcomb BW, Zarek SM, Pollack AZ, Bertone-Johnson ER, Danaher M, Wactawski-Wende J, Gaskins AJ, Schisterman EF. Assessment of anovulation in eumenorrheic women: comparison of ovulation detection algorithms. Fertil Steril. 2014 Aug; 102(2):511-518.e2.
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Martin C, Navarro VM, Simavli S, Vong L, Carroll RS, Lowell BB, Kaiser UB. Leptin-responsive GABAergic neurons regulate fertility through pathways that result in reduced kisspeptinergic tone. J Neurosci. 2014 Apr 23; 34(17):6047-56.
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