"Amiloride" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)
| Descriptor ID |
D000584
|
| MeSH Number(s) |
D03.383.679.149
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Amiloride".
Below are MeSH descriptors whose meaning is more specific than "Amiloride".
This graph shows the total number of publications written about "Amiloride" by people in this website by year, and whether "Amiloride" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Amiloride" by people in Profiles.
-
Daniels SI, Soule EE, Davidoff KS, Bernbaum JG, Hu D, Maeda K, Stahl SJ, Naiman NE, Waheed AA, Freed EO, Wingfield P, Yarchoan R, Davis DA. Activation of virus uptake through induction of macropinocytosis with a novel polymerizing peptide. FASEB J. 2014 Jan; 28(1):106-16.
-
Ch?vez JC, de la Vega-Beltr?n JL, Escoffier J, Visconti PE, Trevi?o CL, Darszon A, Salkoff L, Santi CM. Ion permeabilities in mouse sperm reveal an external trigger for SLO3-dependent hyperpolarization. PLoS One. 2013; 8(4):e60578.
-
Escoffier J, Krapf D, Navarrete F, Darszon A, Visconti PE. Flow cytometry analysis reveals a decrease in intracellular sodium during sperm capacitation. J Cell Sci. 2012 Jan 15; 125(Pt 2):473-85.
-
Hern?ndez-Gonz?lez EO, Sosnik J, Edwards J, Acevedo JJ, Mendoza-Lujambio I, L?pez-Gonz?lez I, Demarco I, Wertheimer E, Darszon A, Visconti PE. Sodium and epithelial sodium channels participate in the regulation of the capacitation-associated hyperpolarization in mouse sperm. J Biol Chem. 2006 Mar 03; 281(9):5623-33.
-
Veron D, Martin RS, Escobar E, Tufaro D, Visconti P, Tezon JG, Arrizurieta EE. Effect of NPPB on chloride (Cl-) transport in distal colon of potassium (K+) adapted rats. Acta Physiol Scand. 1994 May; 151(1):45-50.
-
Foster CD, Honeyman TW, Scheid CR. Alterations in Na(+)-H+ exchange in mesenteric arteries from spontaneously hypertensive rats. Am J Physiol. 1992 Jun; 262(6 Pt 2):H1657-62.
-
Quinn DA, Honeyman TW, Joseph PM, Thompson BT, Hales CA, Scheid CR. Contribution of Na+/H+ exchange to pH regulation in pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol. 1991 Dec; 5(6):586-91.