Diacylglycerol O-Acyltransferase
"Diacylglycerol O-Acyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyses the last step of the TRIACYLGLYCEROL synthesis reaction in which diacylglycerol is covalently joined to LONG-CHAIN ACYL COA to form triglyceride. It was formerly categorized as EC 2.3.1.124.
| Descriptor ID |
D051048
|
| MeSH Number(s) |
D08.811.913.050.387
|
| Concept/Terms |
Diacylglycerol O-Acyltransferase- Diacylglycerol O-Acyltransferase
- Diacylglycerol O Acyltransferase
- O-Acyltransferase, Diacylglycerol
- DAGAT Enzyme
- Palmitoyl-Coenzyme A-sn-1,2-Diacylglycerol Acyltransferase
- A-sn-1,2-Diacylglycerol Acyltransferase, Palmitoyl-Coenzyme
- Acyltransferase, Palmitoyl-Coenzyme A-sn-1,2-Diacylglycerol
- Palmitoyl Coenzyme A sn 1,2 Diacylglycerol Acyltransferase
- Diacylglycerol O-Acyltransferase 1
- Diacylglycerol O Acyltransferase 1
- O-Acyltransferase 1, Diacylglycerol
- Diglyceride Acyltransferase
- Acyltransferase, Diglyceride
- Palmitoyl-CoA-sn-1,2-Diacylglycerol Acyltransferase
- Acyltransferase, Palmitoyl-CoA-sn-1,2-Diacylglycerol
- Palmitoyl CoA sn 1,2 Diacylglycerol Acyltransferase
- Acyl-Coenzyme A Diacyl-glycerol Acyltransferase
- Acyl Coenzyme A Diacyl glycerol Acyltransferase
- Diacylglycerol Acyltransferase
- Acyltransferase, Diacylglycerol
|
Below are MeSH descriptors whose meaning is more general than "Diacylglycerol O-Acyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Diacylglycerol O-Acyltransferase".
This graph shows the total number of publications written about "Diacylglycerol O-Acyltransferase" by people in this website by year, and whether "Diacylglycerol O-Acyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Diacylglycerol O-Acyltransferase" by people in Profiles.
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Wilcock DJ, Badrock AP, Wong CW, Owen R, Guerin M, Southam AD, Johnston H, Telfer BA, Fullwood P, Watson J, Ferguson H, Ferguson J, Lloyd GR, Jankevics A, Dunn WB, Wellbrock C, Lorigan P, Ceol C, Francavilla C, Smith MP, Hurlstone AFL. Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached. Cell Rep. 2022 06 21; 39(12):110995.
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Yenilmez B, Wetoska N, Kelly M, Echeverria D, Min K, Lifshitz L, Alterman JF, Hassler MR, Hildebrand S, DiMarzio C, McHugh N, Vangjeli L, Sousa J, Pan M, Han X, Brehm MA, Khvorova A, Czech MP. An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis. Mol Ther. 2022 03 02; 30(3):1329-1342.
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Haas JT, Winter HS, Lim E, Kirby A, Blumenstiel B, DeFelice M, Gabriel S, Jalas C, Branski D, Grueter CA, Toporovski MS, Walther TC, Daly MJ, Farese RV. DGAT1 mutation is linked to a congenital diarrheal disorder. J Clin Invest. 2012 Dec; 122(12):4680-4.
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Ali AH, Koutsari C, Mundi M, Stegall MD, Heimbach JK, Taler SJ, Nygren J, Thorell A, Bogachus LD, Turcotte LP, Bernlohr D, Jensen MD. Free fatty acid storage in human visceral and subcutaneous adipose tissue: role of adipocyte proteins. Diabetes. 2011 Sep; 60(9):2300-7.
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Koutsari C, Ali AH, Mundi MS, Jensen MD. Storage of circulating free fatty acid in adipose tissue of postabsorptive humans: quantitative measures and implications for body fat distribution. Diabetes. 2011 Aug; 60(8):2032-40.
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Jiang LQ, Garcia-Roves PM, de Castro Barbosa T, Zierath JR. Constitutively active calcineurin in skeletal muscle increases endurance performance and mitochondrial respiratory capacity. Am J Physiol Endocrinol Metab. 2010 Jan; 298(1):E8-E16.