Corticotropin-Releasing Hormone
"Corticotropin-Releasing Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, CRH stimulates the release of ACTH from the PITUITARY GLAND. CRH can also be synthesized in other tissues, such as PLACENTA; ADRENAL MEDULLA; and TESTIS.
| Descriptor ID |
D003346
|
| MeSH Number(s) |
D06.472.699.327.740.140 D12.644.400.400.740.140 D12.644.548.365.740.140 D12.776.631.650.405.740.140
|
| Concept/Terms |
Corticotropin-Releasing Hormone- Corticotropin-Releasing Hormone
- Corticotropin Releasing Hormone
- Corticoliberin
- Corticotropin-Releasing Factor
- Corticotropin Releasing Factor
- Corticotropin-Releasing Factor-41
- Corticotropin Releasing Factor 41
- CRF (ACTH)
- Corticotropin-Releasing Hormone-41
- Corticotropin Releasing Hormone 41
- CRF-41
- ACTH-Releasing Hormone
- ACTH Releasing Hormone
- ACTH-Releasing Factor
- ACTH Releasing Factor
|
Below are MeSH descriptors whose meaning is more general than "Corticotropin-Releasing Hormone".
Below are MeSH descriptors whose meaning is more specific than "Corticotropin-Releasing Hormone".
This graph shows the total number of publications written about "Corticotropin-Releasing Hormone" by people in this website by year, and whether "Corticotropin-Releasing Hormone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 1 | 3 |
| 2014 | 1 | 0 | 1 |
| 2015 | 2 | 2 | 4 |
| 2016 | 1 | 2 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Corticotropin-Releasing Hormone" by people in Profiles.
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Salimando GJ, Hyun M, Boyt KM, Winder DG. BNST GluN2D-Containing NMDA Receptors Influence Anxiety- and Depressive-like Behaviors and ModulateCell-Specific Excitatory/Inhibitory Synaptic Balance. J Neurosci. 2020 05 13; 40(20):3949-3968.
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Hartley ND, Gaulden AD, B?ldi R, Winters ND, Salimando GJ, Rosas-Vidal LE, Jameson A, Winder DG, Patel S. Dynamic remodeling of a basolateral-to-central amygdala glutamatergic circuit across fear states. Nat Neurosci. 2019 12; 22(12):2000-2012.
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Snyder AE, Salimando GJ, Winder DG, Silberman Y. Chronic Intermittent Ethanol and Acute Stress Similarly Modulate BNST CRF Neuron Activity via Noradrenergic Signaling. Alcohol Clin Exp Res. 2019 08; 43(8):1695-1701.
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Fetterly TL, Basu A, Nabit BP, Awad E, Williford KM, Centanni SW, Matthews RT, Silberman Y, Winder DG. a2A-Adrenergic Receptor Activation Decreases Parabrachial Nucleus Excitatory Drive onto BNST CRF Neurons and Reduces Their Activity In Vivo. J Neurosci. 2019 01 16; 39(3):472-484.
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Molas S, DeGroot SR, Zhao-Shea R, Tapper AR. Anxiety and Nicotine Dependence: Emerging Role of the Habenulo-Interpeduncular Axis. Trends Pharmacol Sci. 2017 02; 38(2):169-180.
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Schreiber AL, Lu YL, Baynes BB, Richardson HN, Gilpin NW. Corticotropin-releasing factor in ventromedial prefrontal cortex mediates avoidance of a traumatic stress-paired context. Neuropharmacology. 2017 02; 113(Pt A):323-330.
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Itoga CA, Roltsch Hellard EA, Whitaker AM, Lu YL, Schreiber AL, Baynes BB, Baiamonte BA, Richardson HN, Gilpin NW. Traumatic Stress Promotes Hyperalgesia via Corticotropin-Releasing Factor-1 Receptor (CRFR1) Signaling in Central Amygdala. Neuropsychopharmacology. 2016 09; 41(10):2463-72.
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Edwards S, Little HJ, Richardson HN, Vendruscolo LF. Divergent regulation of distinct glucocorticoid systems in alcohol dependence. Alcohol. 2015 Dec; 49(8):811-6.
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Zhao-Shea R, DeGroot SR, Liu L, Vallaster M, Pang X, Su Q, Gao G, Rando OJ, Martin GE, George O, Gardner PD, Tapper AR. Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal. Nat Commun. 2015 Apr 21; 6:6770.
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Silberman Y, Winder DG. Ethanol and corticotropin releasing factor receptor modulation of central amygdala neurocircuitry: An update and future directions. Alcohol. 2015 May; 49(3):179-84.