An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.

Descriptor ID	D003042
MeSH Number(s)	D02.145.074.722.388 D03.132.889.354 D03.605.084.500.722.388 D03.605.869.388
Concept/Terms	Cocaine Cocaine Cocaine Hydrochloride Cocaine Hydrochloride Hydrochloride, Cocaine Cocaine HCl HCl, Cocaine

Below are MeSH descriptors whose meaning is more general than "Cocaine".

Below are MeSH descriptors whose meaning is related to "Cocaine".

Below are MeSH descriptors whose meaning is more specific than "Cocaine".