"Quinacrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
| Descriptor ID |
D011796
|
| MeSH Number(s) |
D03.633.300.046.250.760
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Quinacrine".
Below are MeSH descriptors whose meaning is more specific than "Quinacrine".
This graph shows the total number of publications written about "Quinacrine" by people in this website by year, and whether "Quinacrine" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Quinacrine" by people in Profiles.
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Seres I, F?ris G, Varga Z, Koszt?czky B, Kassai A, Balogh Z, F?l?p P, Paragh G. The association between angiotensin II-induced free radical generation and membrane fluidity in neutrophils of patients with metabolic syndrome. J Membr Biol. 2006; 214(2):91-8.
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Kohjimoto Y, Honeyman TW, Jonassen J, Gravel K, Kennington L, Scheid CR. Phospholipase A2 mediates immediate early genes in cultured renal epithelial cells: possible role of lysophospholipid. Kidney Int. 2000 Aug; 58(2):638-46.
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Harrison TS, Griffin GE, Levitz SM. Conditional lethality of the diprotic weak bases chloroquine and quinacrine against Cryptococcus neoformans. J Infect Dis. 2000 Jul; 182(1):283-9.
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Kohjimoto Y, Kennington L, Scheid CR, Honeyman TW. Role of phospholipase A2 in the cytotoxic effects of oxalate in cultured renal epithelial cells. Kidney Int. 1999 Oct; 56(4):1432-41.
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Newburger PE, Cohen HJ, Rothchild SB, Hobbins JC, Malawista SE, Mahoney MJ. Prenatal diagnosis of chronic granulomatous disease. N Engl J Med. 1979 Jan 25; 300(4):178-81.