"Muscarinic Agonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that bind to and activate muscarinic cholinergic receptors (RECEPTORS, MUSCARINIC). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate.
Descriptor ID |
D018721
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MeSH Number(s) |
D27.505.519.625.120.140.500 D27.505.696.577.120.140.500
|
Concept/Terms |
Muscarinic Agonists- Muscarinic Agonists
- Agonists, Muscarinic
- Muscarinic Agonist
- Agonist, Muscarinic
- Cholinergic Muscarinic Agonists
- Agonists, Cholinergic Muscarinic
- Muscarinic Agonists, Cholinergic
- Cholinergic Agonist, Muscarinic
- Agonist, Muscarinic Cholinergic
- Muscarinic Cholinergic Agonist
- Cholinergic Agonists, Muscarinic
- Agonists, Muscarinic Cholinergic
- Muscarinic Cholinergic Agonists
|
Below are MeSH descriptors whose meaning is more general than "Muscarinic Agonists".
Below are MeSH descriptors whose meaning is more specific than "Muscarinic Agonists".
This graph shows the total number of publications written about "Muscarinic Agonists" by people in this website by year, and whether "Muscarinic Agonists" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
2000 | 1 | 0 | 1 |
2003 | 1 | 0 | 1 |
2004 | 0 | 1 | 1 |
2005 | 0 | 2 | 2 |
2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Muscarinic Agonists" by people in Profiles.
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Liu L, Heneghan JF, Michael GJ, Stanish LF, Egertov? M, Rittenhouse AR. L- and N-current but not M-current inhibition by M1 muscarinic receptors requires DAG lipase activity. J Cell Physiol. 2008 Jul; 216(1):91-100.
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Hamam BN, Sinai M, Poirier G, Chapman CA. Cholinergic suppression of excitatory synaptic responses in layer II of the medial entorhinal cortex. Hippocampus. 2007; 17(2):103-13.
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Parad RB, Comeau AM, Dorkin HL, Dovey M, Gerstle R, Martin T, O'Sullivan BP. Sweat testing infants detected by cystic fibrosis newborn screening. J Pediatr. 2005 Sep; 147(3 Suppl):S69-72.
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Ethier MF, Cappelluti E, Madison JM. Mechanisms of interleukin-4 effects on calcium signaling in airway smooth muscle cells. J Pharmacol Exp Ther. 2005 Apr; 313(1):127-33.
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Liu L, Roberts ML, Rittenhouse AR. Phospholipid metabolism is required for M1 muscarinic inhibition of N-type calcium current in sympathetic neurons. Eur Biophys J. 2004 May; 33(3):255-64.
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Rufo PA, Lin PW, Andrade A, Jiang L, Rameh L, Flexner C, Alper SL, Lencer WI. Diarrhea-associated HIV-1 APIs potentiate muscarinic activation of Cl- secretion by T84 cells via prolongation of cytosolic Ca2+ signaling. Am J Physiol Cell Physiol. 2004 May; 286(5):C998-C1008.
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Liu L, Rittenhouse AR. Pharmacological discrimination between muscarinic receptor signal transduction cascades with bethanechol chloride. Br J Pharmacol. 2003 Apr; 138(7):1259-70.
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Tissenbaum HA, Hawdon J, Perregaux M, Hotez P, Guarente L, Ruvkun G. A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum. Proc Natl Acad Sci U S A. 2000 Jan 04; 97(1):460-5.
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Ethier MF, Schaefer OP, Samant N, Yamaguchi H, Madison JM. Muscarinic receptor reserve for inhibition of cAMP accumulation in bovine trachealis cells. Am J Physiol. 1996 Feb; 270(2 Pt 1):L199-207.