Injections, Intra-Articular

"Injections, Intra-Articular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Methods of delivering drugs into a joint space.

Descriptor ID	D007270
MeSH Number(s)	E02.319.267.530.380
Concept/Terms	Injections, Intra-Articular Injections, Intra-Articular Injections, Intra Articular Intraarticular Injections Injections, Intraarticular Injection, Intraarticular Intraarticular Injection Intra-Articular Injections Injection, Intra-Articular Intra Articular Injections Intra-Articular Injection

Below are MeSH descriptors whose meaning is more general than "Injections, Intra-Articular".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Therapeutics [E02]
Drug Therapy [E02.319]
Drug Administration Routes [E02.319.267]
Injections [E02.319.267.530]
Injections, Intra-Articular [E02.319.267.530.380]

Below are MeSH descriptors whose meaning is related to "Injections, Intra-Articular".

Below are MeSH descriptors whose meaning is more specific than "Injections, Intra-Articular".

Injections, Intra-Articular
Viscosupplementation

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Injections, Intra-Articular" by people in this website by year, and whether "Injections, Intra-Articular" was a major or minor topic of these publications.

Bar chart showing 36 publications over 19 distinct years, with a maximum of 5 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	0	1	1
1999	0	1	1
2003	0	2	2
2008	0	1	1
2009	0	1	1
2011	0	1	1
2012	0	1	1
2013	0	2	2
2015	0	2	2
2016	0	2	2
2017	1	4	5
2018	0	3	3
2019	0	3	3
2020	0	4	4
2021	0	1	1
2022	0	1	1
2024	0	1	1
2025	0	3	3

Below are the most recent publications written about "Injections, Intra-Articular" by people in Profiles.

Tambiah J, Kennedy S, Swearingen C, McAlindon T, Yazici Y. Impact of structural severity on outcomes in knee osteoarthritis: an analysis of data from phase 2 and phase 3 lorecivivint clinical trials. Rheumatology (Oxford). 2025 May 01; 64(5):2583-2590.

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Yazici Y, Tambiah JRS, Swearingen CJ, Lopez VA, Kennedy S, Fineman MS, Simsek I, Solomon E, Mcalindon TE. A Phase 3, 28-week, multicentre, randomised, double-blind, placebo-controlled trial (OA-10) to evaluate the efficacy and safety of a single injection of lorecivivint in the target knee joint of moderately to severely symptomatic osteoarthritis patients. Clin Exp Rheumatol. 2025 May; 43(5):847-853.

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Yazici Y, Tambiah JRS, Swearingen CJ, Britt J, Kennedy S, Fineman MS, Simsek I, Solomon E, McAlindon TE. A Phase 3, 56-week, randomised, double-blind, placebo-controlled study (OA-11) utilising patient-reported and radiographic outcomes evaluating the efficacy and safety of a lorecivivint injection in patients with moderate to severe knee osteoarthritis. Clin Exp Rheumatol. 2025 May; 43(5):854-860.

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Parhar D, Dhatt R, Liu SH, Slater A, Liu L, Khan N, Badii M, Masri B, Liu DM. Advances in Interventional Radiology Technology for the Treatment of Knee Osteoarthritis. Orthop Clin North Am. 2024 Oct; 55(4):435-443.

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Tambiah JRS, Simsek I, Swearingen CJ, Kennedy S, Cole BJ, McAlindon TE, Yazici Y. Comparing Patient-Reported Outcomes From Sham and Saline-Based Placebo Injections for Knee Osteoarthritis: Data From a Randomized Clinical Trial of Lorecivivint. Am J Sports Med. 2022 Mar; 50(3):630-636.

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Yazici Y, McAlindon TE, Gibofsky A, Lane NE, Lattermann C, Skrepnik N, Swearingen CJ, Simsek I, Ghandehari H, DiFrancesco A, Gibbs J, Tambiah JRS, Hochberg MC. A Phase 2b randomized trial of lorecivivint, a novel intra-articular CLK2/DYRK1A inhibitor and Wnt pathway modulator for knee osteoarthritis. Osteoarthritis Cartilage. 2021 05; 29(5):654-666.

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Arden NK, Perry TA, Bannuru RR, Bruy?re O, Cooper C, Haugen IK, Hochberg MC, McAlindon TE, Mobasheri A, Reginster JY. Non-surgical management of knee osteoarthritis: comparison of ESCEO and OARSI 2019 guidelines. Nat Rev Rheumatol. 2021 01; 17(1):59-66.

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Yazici Y, McAlindon TE, Gibofsky A, Lane NE, Clauw D, Jones M, Bergfeld J, Swearingen CJ, DiFrancesco A, Simsek I, Tambiah J, Hochberg MC. Lorecivivint, a Novel Intraarticular CDC-like Kinase 2 and Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A Inhibitor and Wnt Pathway Modulator for the Treatment of Knee Osteoarthritis: A Phase II Randomized Trial. Arthritis Rheumatol. 2020 10; 72(10):1694-1706.

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Lanza E, Piccoli F, Intrieri C, Muglia R, Politi LS, Borroni M, Castagna A, Sconfienza LM. US-guided percutaneous irrigation of calcific tendinopathy of the rotator cuff in patients with or without previous external shockwave therapy. Radiol Med. 2021 Jan; 126(1):117-123.

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McAlindon TE, Harkey MS, Ward RJ, Hochberg MC, Driban JB. Intra-articular Corticosteroid Injections in the Hip and Knee: Perhaps Not as Dangerous as They Want You to Believe? Radiology. 2020 04; 295(1):249-250.

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