Hemoglobinuria, Paroxysmal
"Hemoglobinuria, Paroxysmal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.
| Descriptor ID |
D006457
|
| MeSH Number(s) |
C15.378.071.141.560 C15.378.190.625.460
|
| Concept/Terms |
Paroxysmal Cold Hemoglobinuria- Paroxysmal Cold Hemoglobinuria
- Hemoglobinuria, Paroxysmal Cold
- Paroxysmal Hemoglobinuria, Cold
- Cold Paroxysmal Hemoglobinuria
- Hemoglobinuria, Cold Paroxysmal
Paroxysmal Nocturnal Hemoglobinuria- Paroxysmal Nocturnal Hemoglobinuria
- Hemoglobinuria, Paroxysmal Nocturnal
- Marchiafava-Micheli Syndrome
- Marchiafava Micheli Syndrome
- Syndrome, Marchiafava-Micheli
- Paroxysmal Hemoglobinuria, Nocturnal
- Hemoglobinuria, Nocturnal Paroxysmal
- Nocturnal Paroxysmal Hemoglobinuria
|
Below are MeSH descriptors whose meaning is more general than "Hemoglobinuria, Paroxysmal".
Below are MeSH descriptors whose meaning is more specific than "Hemoglobinuria, Paroxysmal".
This graph shows the total number of publications written about "Hemoglobinuria, Paroxysmal" by people in this website by year, and whether "Hemoglobinuria, Paroxysmal" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Hemoglobinuria, Paroxysmal" by people in Profiles.
-
DeZern AE, Uknis M, Yuan X, Mukhina GL, Varela J, Saye J, Pu J, Brodsky RA. Complement blockade with a C1 esterase inhibitor in paroxysmal nocturnal hemoglobinuria. Exp Hematol. 2014 Oct; 42(10):857-61.e1.
-
Wang SA, Pozdnyakova O, Jorgensen JL, Medeiros LJ, Stachurski D, Anderson M, Raza A, Woda BA. Detection of paroxysmal nocturnal hemoglobinuria clones in patients with myelodysplastic syndromes and related bone marrow diseases, with emphasis on diagnostic pitfalls and caveats. Haematologica. 2009 Jan; 94(1):29-37.
-
Gehrs BC, Friedberg RC. Autoimmune hemolytic anemia. Am J Hematol. 2002 Apr; 69(4):258-71.
-
Golenbock DT, Bach RR, Lichenstein H, Juan TS, Tadavarthy A, Moldow CF. Soluble CD14 promotes LPS activation of CD14-deficient PNH monocytes and endothelial cells. J Lab Clin Med. 1995 May; 125(5):662-71.
-
Schwarting GA, Kundu SK, Marcus DM. Reaction of antibodies that cause paroxysmal cold hemoglobinuria (PCH) with globoside and Forssman glycosphingolipids. Blood. 1979 Feb; 53(2):186-92.