"Microsomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Artifactual vesicles formed from the endoplasmic reticulum when cells are disrupted. They are isolated by differential centrifugation and are composed of three structural features: rough vesicles, smooth vesicles, and ribosomes. Numerous enzyme activities are associated with the microsomal fraction. (Glick, Glossary of Biochemistry and Molecular Biology, 1990; from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
| Descriptor ID |
D008861
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| MeSH Number(s) |
A11.284.835.540
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Microsomes".
Below are MeSH descriptors whose meaning is more specific than "Microsomes".
This graph shows the total number of publications written about "Microsomes" by people in this website by year, and whether "Microsomes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
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Below are the most recent publications written about "Microsomes" by people in Profiles.
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Parkinson OT, Teitelbaum AM, Whittington D, Kelly EJ, Rettie AE. Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity. Drug Metab Dispos. 2016 10; 44(10):1598-602.
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Smulan LJ, Ding W, Freinkman E, Gujja S, Edwards YJK, Walker AK. Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation. Cell Rep. 2016 06 28; 16(1):9-18.
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Nalam MN, Ali A, Reddy GS, Cao H, Anjum SG, Altman MD, Yilmaz NK, Tidor B, Rana TM, Schiffer CA. Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance. Chem Biol. 2013 Sep 19; 20(9):1116-24.
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Nakano M, Kelly EJ, Rettie AE. Expression and characterization of CYP4V2 as a fatty acid omega-hydroxylase. Drug Metab Dispos. 2009 Nov; 37(11):2119-22.
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Farwell AP, Leonard JL. Effect of methyl iodide on deiodinase activity. Inhal Toxicol. 2009 May; 21(6):497-504.
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Guo J, Liu A, Cao H, Luo Y, Pezzuto JM, van Breemen RB. Biotransformation of the chemopreventive agent 2',4',4-trihydroxychalcone (isoliquiritigenin) by UDP-glucuronosyltransferases. Drug Metab Dispos. 2008 Oct; 36(10):2104-12.
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Dougan SK, Rava P, Hussain MM, Blumberg RS. MTP regulated by an alternate promoter is essential for NKT cell development. J Exp Med. 2007 Mar 19; 204(3):533-45.
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Ghosh P, Hale EA, Mayur K, Seddon J, Lakshman MR. Effects of chronic alcohol treatment on the synthesis, sialylation, and disposition of nascent apolipoprotein E by peritoneal macrophages of rats. Am J Clin Nutr. 2000 Jul; 72(1):190-8.
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Seymour NE, Spector SA, Andersen DK, Elm MS, Whitcomb DC. Overexpression of hepatic pancreatic polypeptide receptors in chronic pancreatitis. J Surg Res. 1998 Apr; 76(1):47-52.
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Lucchesi PA, Cooney RA, Mangsen-Baker C, Honeyman TW, Scheid CR. Assessment of transport capacity of plasmalemmal Ca2+ pump in smooth muscle. Am J Physiol. 1988 Aug; 255(2 Pt 1):C226-36.