"Gene Conversion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The asymmetrical segregation of genes during replication which leads to the production of non-reciprocal recombinant strands and the apparent conversion of one allele into another. Thus, e.g., the meiotic products of an Aa individual may be AAAa or aaaA instead of AAaa, i.e., the A allele has been converted into the a allele or vice versa.
Descriptor ID |
D005785
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MeSH Number(s) |
G05.728.615.475
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Concept/Terms |
Gene Conversion- Gene Conversion
- Conversion, Gene
- Conversions, Gene
- Gene Conversions
Polar Recombination- Polar Recombination
- Polar Recombinations
- Recombination, Polar
- Recombinations, Polar
|
Below are MeSH descriptors whose meaning is more general than "Gene Conversion".
Below are MeSH descriptors whose meaning is more specific than "Gene Conversion".
This graph shows the total number of publications written about "Gene Conversion" by people in this website by year, and whether "Gene Conversion" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
1996 | 1 | 0 | 1 |
1997 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Conversion" by people in Profiles.
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Hill DA, de la Serna IL, Veal TM, Imbalzano AN. BRCA1 interacts with dominant negative SWI/SNF enzymes without affecting homologous recombination or radiation-induced gene activation of p21 or Mdm2. J Cell Biochem. 2004 Apr 01; 91(5):987-98.
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Meyer A, Parng CL, Hansal SA, Osborne BA, Goldsby RA. Immunoglobulin gene diversification in cattle. Int Rev Immunol. 1997; 15(3-4):165-83.
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Parng CL, Hansal S, Goldsby RA, Osborne BA. Gene conversion contributes to Ig light chain diversity in cattle. J Immunol. 1996 Dec 15; 157(12):5478-86.
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Parng CL, Hansal S, Goldsby RA, Osborne BA. Diversification of bovine lambda-light chain genes. Ann N Y Acad Sci. 1995 Sep 29; 764:155-7.
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Ferguson SE, Cancro MP, Osborne BA. Analysis of a novel VHS107 haplotype in CLA-2 and WSA mice. Evidence for gene conversion among IgVH genes in outbred populations. J Exp Med. 1989 Dec 01; 170(6):1811-23.
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Ferguson SE, Rudikoff S, Osborne BA. Interaction and sequence diversity among T15 VH genes in CBA/J mice. J Exp Med. 1988 Oct 01; 168(4):1339-49.