Phosphatidylcholine-Sterol O-Acyltransferase
"Phosphatidylcholine-Sterol O-Acyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma.
| Descriptor ID |
D007862
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| MeSH Number(s) |
D08.811.913.050.625
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| Concept/Terms |
Phosphatidylcholine-Sterol O-Acyltransferase- Phosphatidylcholine-Sterol O-Acyltransferase
- O-Acyltransferase, Phosphatidylcholine-Sterol
- Phosphatidylcholine Sterol O Acyltransferase
- Lecithin Cholesterol Acyltransferase
- Acyltransferase, Lecithin Cholesterol
- Cholesterol Acyltransferase, Lecithin
- Lecithin Acyltransferase
- Acyltransferase, Lecithin
- Cholesterol Ester Lysolecithin Acyltransferase
- Phosophatidylcholine-Sterol Acyltransferase
- Acyltransferase, Phosophatidylcholine-Sterol
- Phosophatidylcholine Sterol Acyltransferase
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Below are MeSH descriptors whose meaning is more general than "Phosphatidylcholine-Sterol O-Acyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylcholine-Sterol O-Acyltransferase".
This graph shows the total number of publications written about "Phosphatidylcholine-Sterol O-Acyltransferase" by people in this website by year, and whether "Phosphatidylcholine-Sterol O-Acyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphatidylcholine-Sterol O-Acyltransferase" by people in Profiles.
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Roshan B, Ganda OP, Desilva R, Ganim RB, Ward E, Haessler SD, Polisecki EY, Asztalos BF, Schaefer EJ. Homozygous lecithin:cholesterol acyltransferase (LCAT) deficiency due to a new loss of function mutation and review of the literature. J Clin Lipidol. 2011 Nov-Dec; 5(6):493-9.
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Harangi M, Mirdamadi HZ, Seres I, Sztanek F, Moln?r M, Kassai A, Derd?k Z, Illy?s L, Paragh G. Atorvastatin effect on the distribution of high-density lipoprotein subfractions and human paraoxonase activity. Transl Res. 2009 Apr; 153(4):190-8.
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Kassai A, Illy?s L, Mirdamadi HZ, Seres I, Kalm?r T, Audikovszky M, Paragh G. The effect of atorvastatin therapy on lecithin:cholesterol acyltransferase, cholesteryl ester transfer protein and the antioxidant paraoxonase. Clin Biochem. 2007 Jan; 40(1-2):1-5.
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Hojnacki JL, Cluette-Brown JE, Deschenes RN, Mulligan JJ, Osmolski TV, Rencricca NJ, Barboriak JJ. Alcohol produces dose-dependent antiatherogenic and atherogenic plasma lipoprotein responses. Proc Soc Exp Biol Med. 1992 May; 200(1):67-77.
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Hojnacki JL, Deschenes RN, Cluette-Brown JE, Mulligan JJ, Osmolski TV, Rencricca NJ, Barboriak JJ. Effect of drinking pattern on plasma lipoproteins and body weight. Atherosclerosis. 1991 May; 88(1):49-59.