 DNA-Directed RNA Polymerases
"DNA-Directed RNA Polymerases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992).
| Descriptor ID |
D012321
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| MeSH Number(s) |
D08.811.913.696.445.735.270
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| Concept/Terms |
DNA-Directed RNA Polymerases- DNA-Directed RNA Polymerases
- DNA Directed RNA Polymerases
- Polymerases, DNA-Directed RNA
- RNA Polymerases, DNA-Directed
- RNA Polymerase
- Polymerase, RNA
- Transcriptases
- DNA-Directed RNA Polymerase
- DNA Directed RNA Polymerase
- Polymerase, DNA-Directed RNA
- RNA Polymerase, DNA-Directed
- DNA-Dependent RNA Polymerases
- DNA Dependent RNA Polymerases
- Polymerases, DNA-Dependent RNA
- RNA Polymerases, DNA-Dependent
- RNA Polymerases
- Polymerases, RNA
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Below are MeSH descriptors whose meaning is more general than "DNA-Directed RNA Polymerases".
Below are MeSH descriptors whose meaning is more specific than "DNA-Directed RNA Polymerases".
This graph shows the total number of publications written about "DNA-Directed RNA Polymerases" by people in this website by year, and whether "DNA-Directed RNA Polymerases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1989 | 0 | 1 | 1 | | 1995 | 0 | 2 | 2 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 3 | 0 | 3 | | 2002 | 2 | 0 | 2 | | 2003 | 0 | 2 | 2 | | 2004 | 4 | 0 | 4 | | 2005 | 1 | 2 | 3 | | 2006 | 2 | 0 | 2 | | 2007 | 3 | 2 | 5 | | 2009 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 2 | 0 | 2 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 2 | 3 | | 2015 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA-Directed RNA Polymerases" by people in Profiles.
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Demo G, Rasouly A, Vasilyev N, Svetlov V, Loveland AB, Diaz-Avalos R, Grigorieff N, Nudler E, Korostelev AA. Structure of RNA polymerase bound to ribosomal 30S subunit. Elife. 2017 10 13; 6.
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Liang B, Li Z, Jenni S, Rahmeh AA, Morin BM, Grant T, Grigorieff N, Harrison SC, Whelan SPJ. Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy. Cell. 2015 Jul 16; 162(2):314-327.
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Jones DL, Brewster RC, Phillips R. Promoter architecture dictates cell-to-cell variability in gene expression. Science. 2014 Dec 19; 346(6216):1533-6.
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Weinert FM, Brewster RC, Rydenfelt M, Phillips R, Kegel WK. Scaling of gene expression with transcription-factor fugacity. Phys Rev Lett. 2014 Dec 19; 113(25):258101.
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Martin CT, Theis K. Closed for business: exit-channel coupling to active site conformation in bacterial RNA polymerase. Nat Struct Mol Biol. 2014 Sep; 21(9):741-2.
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Samanta S, Martin CT. Insights into the mechanism of initial transcription in Escherichia coli RNA polymerase. J Biol Chem. 2013 Nov 01; 288(44):31993-2003.
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Brewster RC, Jones DL, Phillips R. Tuning promoter strength through RNA polymerase binding site design in Escherichia coli. PLoS Comput Biol. 2012; 8(12):e1002811.
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RamÃrez-Tapia LE, Martin CT. New insights into the mechanism of initial transcription: the T7 RNA polymerase mutant P266L transitions to elongation at longer RNA lengths than wild type. J Biol Chem. 2012 Oct 26; 287(44):37352-61.
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Liu L, Sanosaka M, Lei S, Bestwick ML, Frey JH, Surovtseva YV, Shadel GS, Cooper MP. LRP130 protein remodels mitochondria and stimulates fatty acid oxidation. J Biol Chem. 2011 Dec 02; 286(48):41253-64.
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Vahia AV, Martin CT. Direct tests of the energetic basis of abortive cycling in transcription. Biochemistry. 2011 Aug 16; 50(32):7015-22.
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