DNA-Directed RNA Polymerases
"DNA-Directed RNA Polymerases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992).
Descriptor ID |
D012321
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MeSH Number(s) |
D08.811.913.696.445.735.270
|
Concept/Terms |
DNA-Directed RNA Polymerases- DNA-Directed RNA Polymerases
- DNA Directed RNA Polymerases
- Polymerases, DNA-Directed RNA
- RNA Polymerases, DNA-Directed
- RNA Polymerase
- Polymerase, RNA
- Transcriptases
- DNA-Directed RNA Polymerase
- DNA Directed RNA Polymerase
- Polymerase, DNA-Directed RNA
- RNA Polymerase, DNA-Directed
- DNA-Dependent RNA Polymerases
- DNA Dependent RNA Polymerases
- Polymerases, DNA-Dependent RNA
- RNA Polymerases, DNA-Dependent
- RNA Polymerases
- Polymerases, RNA
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Below are MeSH descriptors whose meaning is more general than "DNA-Directed RNA Polymerases".
Below are MeSH descriptors whose meaning is more specific than "DNA-Directed RNA Polymerases".
This graph shows the total number of publications written about "DNA-Directed RNA Polymerases" by people in this website by year, and whether "DNA-Directed RNA Polymerases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 2 | 2 |
1996 | 0 | 1 | 1 |
1997 | 1 | 0 | 1 |
1998 | 1 | 0 | 1 |
2000 | 0 | 1 | 1 |
2001 | 3 | 0 | 3 |
2002 | 1 | 0 | 1 |
2003 | 0 | 2 | 2 |
2004 | 4 | 0 | 4 |
2005 | 1 | 2 | 3 |
2006 | 2 | 0 | 2 |
2007 | 3 | 2 | 5 |
2009 | 1 | 1 | 2 |
2010 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2012 | 2 | 0 | 2 |
2013 | 1 | 0 | 1 |
2014 | 1 | 3 | 4 |
2015 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
2019 | 2 | 0 | 2 |
2020 | 1 | 1 | 2 |
2021 | 3 | 1 | 4 |
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Below are the most recent publications written about "DNA-Directed RNA Polymerases" by people in Profiles.
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Guharajan S, Chhabra S, Parisutham V, Brewster RC. Quantifying the regulatory role of individual transcription factors in Escherichia coli. Cell Rep. 2021 11 09; 37(6):109952.
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Gopalan S, Wang Y, Harper NW, Garber M, Fazzio TG. Simultaneous profiling of multiple chromatin proteins in the same cells. Mol Cell. 2021 11 18; 81(22):4736-4746.e5.
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Labuz DF, Cunningham A, Tobias J, Dixon A, Dewey E, Marenco CW, Escobar MA, Hazeltine MD, Cleary MA, Kotagal M, Falcone RA, Fallon SC, Naik-Mathuria B, MacArthur T, Klinkner DB, Shah A, Chernoguz A, Orioles A, Zagel A, Gosain A, Knaus M, Hamilton NA, Jafri MA. Venous thromboembolic risk stratification in pediatric trauma: A Pediatric Trauma Society Research Committee multicenter analysis. J Trauma Acute Care Surg. 2021 10 01; 91(4):605-611.
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Cavac E, RamÃrez-Tapia LE, Martin CT. High-salt transcription of DNA cotethered with T7 RNA polymerase to beads generates increased yields of highly pure RNA. J Biol Chem. 2021 09; 297(3):100999.
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Miao X, Sun T, Golan M, Mager J, Cui W. Loss of POLR1D results in embryonic lethality prior to blastocyst formation in mice. Mol Reprod Dev. 2020 11; 87(11):1152-1158.
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Ali MZ, Choubey S, Das D, Brewster RC. Probing Mechanisms of Transcription Elongation Through Cell-to-Cell Variability of RNA Polymerase. Biophys J. 2020 04 07; 118(7):1769-1781.
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Gholamalipour Y, Johnson WC, Martin CT. Efficient inhibition of RNA self-primed extension by addition of competing 3'-capture DNA-improved RNA synthesis by T7 RNA polymerase. Nucleic Acids Res. 2019 11 04; 47(19):e118.
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Jin H, Lindblad P, Bhaya D. Building an Inducible T7 RNA Polymerase/T7 Promoter Circuit in Synechocystis sp. PCC6803. ACS Synth Biol. 2019 04 19; 8(4):655-660.
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Gholamalipour Y, Karunanayake Mudiyanselage A, Martin CT. 3' end additions by T7 RNA polymerase are RNA self-templated, distributive and diverse in character-RNA-Seq analyses. Nucleic Acids Res. 2018 10 12; 46(18):9253-9263.
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Demo G, Rasouly A, Vasilyev N, Svetlov V, Loveland AB, Diaz-Avalos R, Grigorieff N, Nudler E, Korostelev AA. Structure of RNA polymerase bound to ribosomal 30S subunit. Elife. 2017 10 13; 6.