"Clarithromycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
| Descriptor ID |
D017291
|
| MeSH Number(s) |
D02.540.576.500.992.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Clarithromycin".
Below are MeSH descriptors whose meaning is more specific than "Clarithromycin".
This graph shows the total number of publications written about "Clarithromycin" by people in this website by year, and whether "Clarithromycin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Clarithromycin" by people in Profiles.
-
Zhang S, Lee DS, Morrissey R, Aponte-Pieras JR, Rogers AB, Moss SF. Early or late antibiotic intervention prevents Helicobacter pylori-induced gastric cancer in a mouse model. Cancer Lett. 2015 Apr 10; 359(2):345-51.
-
Walkey AJ, Wiener RS. Macrolide antibiotics and survival in patients with acute lung injury. Chest. 2012 May; 141(5):1153-1159.
-
Mansour NM, Hashash JG, El-Halabi M, Ghaith O, Maasri K, Sukkarieh I, Malli A, Sharara AI. A randomized trial of standard-dose versus half-dose rabeprazole, clarithromycin, and amoxicillin in the treatment of Helicobacter pylori infection. Eur J Gastroenterol Hepatol. 2011 Oct; 23(10):865-70.
-
Zuckerman JM, Qamar F, Bono BR. Macrolides, ketolides, and glycylcyclines: azithromycin, clarithromycin, telithromycin, tigecycline. Infect Dis Clin North Am. 2009 Dec; 23(4):997-1026, ix-x.
-
Lee CW, Rickman B, Rogers AB, Ge Z, Wang TC, Fox JG. Helicobacter pylori eradication prevents progression of gastric cancer in hypergastrinemic INS-GAS mice. Cancer Res. 2008 May 01; 68(9):3540-8.
-
Rowe BH, Campbell SG, Boudreaux ED, Colman I, Abu-Laban RB, Sivilotti ML, Clark S, Camargo CA. Community-acquired pneumonia in North American emergency departments: drug resistance and treatment success with clarithromycin. Acad Emerg Med. 2007 Jul; 14(7):607-15.
-
Bochenek WJ, Peters S, Fraga PD, Wang W, Mack ME, Osato MS, El-Zimaity HM, Davis KD, Graham DY. Eradication of Helicobacter pylori by 7-day triple-therapy regimens combining pantoprazole with clarithromycin, metronidazole, or amoxicillin in patients with peptic ulcer disease: results of two double-blind, randomized studies. Helicobacter. 2003 Dec; 8(6):626-42.
-
Keiser P, Nassar N, Skiest D, Rademacher S, Smith JW. A retrospective study of the addition of ciprofloxacin to clarithromycin and ethambutol in the treatment of disseminated Mycobacterium avium complex infection. Int J STD AIDS. 1999 Dec; 10(12):791-4.
-
Hoffman JS, Katz LM, Cave DR. Efficacy of a 1-week regimen of ranitidine bismuth citrate in combination with metronidazole and clarithromycin for Helicobacter pylori eradication. Aliment Pharmacol Ther. 1999 Apr; 13(4):503-6.
-
Gr?bel P, Cave DR. Factors affecting solubility and penetration of clarithromycin through gastric mucus. Aliment Pharmacol Ther. 1998 Jun; 12(6):569-76.