"Theophylline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
| Descriptor ID |
D013806
|
| MeSH Number(s) |
D03.132.960.751 D03.633.100.759.758.824.751
|
| Concept/Terms |
Theophylline- Theophylline
- 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
- 1,3-Dimethylxanthine
- 1,3 Dimethylxanthine
|
Below are MeSH descriptors whose meaning is more general than "Theophylline".
Below are MeSH descriptors whose meaning is more specific than "Theophylline".
This graph shows the total number of publications written about "Theophylline" by people in this website by year, and whether "Theophylline" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Theophylline" by people in Profiles.
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Cazzola M, Calzetta L, Barnes PJ, Criner GJ, Martinez FJ, Papi A, Gabriella Matera M. Efficacy and safety profile of xanthines in COPD: a network meta-analysis. Eur Respir Rev. 2018 Jun 30; 27(148).
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Nigwekar SU, Weiser JM, Kalim S, Xu D, Wibecan JL, Dougherty SM, Mercier-Lafond L, Corapi KM, Eneanya ND, Holbrook EH, Brown D, Thadhani RI, Paunescu TG. Characterization and Correction of Olfactory Deficits in Kidney Disease. J Am Soc Nephrol. 2017 Nov; 28(11):3395-3403.
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Osowski A, Pietrzak M, Wieczorek Z, Wieczorek J. Natural compounds in the human diet and their ability to bind mutagens prevents DNA-mutagen intercalation. J Toxicol Environ Health A. 2010; 73(17-18):1141-9.
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Hsu PY, Kotin RM, Yang YW. Glucose- and metabolically regulated hepatic insulin gene therapy for diabetes. Pharm Res. 2008 Jun; 25(6):1460-8.
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Wierzchowski J, Pietrzak M, Szelag M, Wroczynski P. Salivary aldehyde dehydrogenase--reversible oxidation of the enzyme and its inhibition by caffeine, investigated using fluorimetric method. Arch Oral Biol. 2008 May; 53(5):423-8.
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Doherty DE, Chapman KR, Martinez FJ, Belfer MH. The value of early diagnosis for effective management of chronic obstructive pulmonary disease. J Fam Pract. 2007 Oct; 56(10 Suppl Value):S1-24.
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Wang G, Dayanithi G, Custer EE, Lemos JR. Adenosine inhibition via A(1) receptor of N-type Ca(2+) current and peptide release from isolated neurohypophysial terminals of the rat. J Physiol. 2002 May 01; 540(Pt 3):791-802.
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Mitra SP, Carraway RE. Synergistic effects of neurotensin and beta-adrenergic agonist on 3,5-cyclic adenosine monophosphate accumulation and DNA synthesis in prostate cancer PC3 cells. Biochem Pharmacol. 1999 Jun 15; 57(12):1391-7.
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Mody M, Lazarus AH, Semple JW, Freedman J. Preanalytical requirements for flow cytometric evaluation of platelet activation: choice of anticoagulant. Transfus Med. 1999 Jun; 9(2):147-54.
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Eshleman SH, Shaw LM. Massive theophylline overdose with atypical metabolic abnormalities. Clin Chem. 1990 Feb; 36(2):398-9.