Receptors, TNF-Related Apoptosis-Inducing Ligand
"Receptors, TNF-Related Apoptosis-Inducing Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved DEATH DOMAINS that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.
| Descriptor ID |
D053220
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| MeSH Number(s) |
D12.776.543.750.690.600 D12.776.543.750.705.852.760.396
|
| Concept/Terms |
Receptors, TNF-Related Apoptosis-Inducing Ligand- Receptors, TNF-Related Apoptosis-Inducing Ligand
- Receptors, TNF Related Apoptosis Inducing Ligand
- Tumor Necrosis Factor Receptor Superfamily, Member 10
- TRAIL Receptors
- Receptors, TRAIL
- Receptors, Tumor Necrosis Factor, Member 10
- TNF-Related Apoptosis-Inducing Ligand Receptors
- TNF Related Apoptosis Inducing Ligand Receptors
Receptors, Tumor Necrosis Factor, Member 10d- Receptors, Tumor Necrosis Factor, Member 10d
- Decoy Receptor 2, Tumor Necrosis Factor
- Receptor, TRAIL-4
- Receptor, TRAIL 4
- TRAIL-4 Receptor
- DCR2 Receptor
- Receptor, DCR2
- CD264 Antigen
- Antigen, CD264
- TRAIL Receptor 4
- Receptor 4, TRAIL
Receptors, Tumor Necrosis Factor, Member 10a- Receptors, Tumor Necrosis Factor, Member 10a
- Tumor Necrosis Factor Receptor Superfamily, Member 10a
- APO2 Receptor
- Receptor, APO2
- Receptor, TRAIL-1
- Receptor, TRAIL 1
- TRAIL-1 Receptor
- TRAIL Receptor 1
- DR4 Receptor
- Receptor, DR4
- CD261 Antigen
- Antigen, CD261
- Death Receptor-4
- Death Receptor 4
- Receptor-4, Death
Receptors, Tumor Necrosis Factor, Member 10b- Receptors, Tumor Necrosis Factor, Member 10b
- TRAIL Receptor 2
- Receptor, TRAIL-2
- Receptor, TRAIL 2
- TRAIL-2 Receptor
- DR5 Receptor
- Receptor, DR5
- Tumor Necrosis Factor Receptor Superfamily, Member 10b
- TNF-Related Apoptosis-Inducing Ligand Receptor 2
- TNF Related Apoptosis Inducing Ligand Receptor 2
- CD262 Antigen
- Antigen, CD262
- Death Receptor-5
- Death Receptor 5
|
Below are MeSH descriptors whose meaning is more general than "Receptors, TNF-Related Apoptosis-Inducing Ligand".
Below are MeSH descriptors whose meaning is more specific than "Receptors, TNF-Related Apoptosis-Inducing Ligand".
This graph shows the total number of publications written about "Receptors, TNF-Related Apoptosis-Inducing Ligand" by people in this website by year, and whether "Receptors, TNF-Related Apoptosis-Inducing Ligand" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, TNF-Related Apoptosis-Inducing Ligand" by people in Profiles.
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Menon LG, Kelly K, Yang HW, Kim SK, Black PM, Carroll RS. Human bone marrow-derived mesenchymal stromal cells expressing S-TRAIL as a cellular delivery vehicle for human glioma therapy. Stem Cells. 2009 Sep; 27(9):2320-30.
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Chan FK. Three is better than one: pre-ligand receptor assembly in the regulation of TNF receptor signaling. Cytokine. 2007 Feb; 37(2):101-7.
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Clancy L, Mruk K, Archer K, Woelfel M, Mongkolsapaya J, Screaton G, Lenardo MJ, Chan FK. Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis. Proc Natl Acad Sci U S A. 2005 Dec 13; 102(50):18099-104.
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Tsai HF, Lai JJ, Chou AH, Wang TF, Wu CS, Hsu PN. Induction of costimulation of human CD4 T cells by tumor necrosis factor-related apoptosis-inducing ligand: possible role in T cell activation in systemic lupus erythematosus. Arthritis Rheum. 2004 Feb; 50(2):629-39.
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Ramp U, Caliskan E, Mahotka C, Krieg A, Heikaus S, Gabbert HE, Gerharz CD. Apoptosis induction in renal cell carcinoma by TRAIL and gamma-radiation is impaired by deficient caspase-9 cleavage. Br J Cancer. 2003 Jun 02; 88(11):1800-7.
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Bachelder RE, Wendt MA, Fujita N, Tsuruo T, Mercurio AM. The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis. J Biol Chem. 2001 Sep 14; 276(37):34702-7.
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Lin Y, Devin A, Cook A, Keane MM, Kelliher M, Lipkowitz S, Liu ZG. The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase. Mol Cell Biol. 2000 Sep; 20(18):6638-45.