Troponin I

"Troponin I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.

Descriptor ID	D019210
MeSH Number(s)	D05.500.945.925 D05.750.078.730.825.925 D12.776.210.500.910.925 D12.776.220.525.825.925
Concept/Terms	Troponin I Troponin I Troponin-I Troponin I3 Troponin I3 Troponin I2 Troponin I2 Troponin I1 Troponin I1

Below are MeSH descriptors whose meaning is more general than "Troponin I".

Chemicals and Drugs [D]
Macromolecular Substances [D05]
Multiprotein Complexes [D05.500]
Troponin [D05.500.945]
Troponin I [D05.500.945.925]
Polymers [D05.750]
Biopolymers [D05.750.078]
Microfilament Proteins [D05.750.078.730]
Troponin [D05.750.078.730.825]
Troponin I [D05.750.078.730.825.925]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Contractile Proteins [D12.776.210]
Muscle Proteins [D12.776.210.500]
Troponin [D12.776.210.500.910]
Troponin I [D12.776.210.500.910.925]
Cytoskeletal Proteins [D12.776.220]
Microfilament Proteins [D12.776.220.525]
Troponin [D12.776.220.525.825]
Troponin I [D12.776.220.525.825.925]

Below are MeSH descriptors whose meaning is related to "Troponin I".

Below are MeSH descriptors whose meaning is more specific than "Troponin I".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Troponin I" by people in this website by year, and whether "Troponin I" was a major or minor topic of these publications.

Bar chart showing 23 publications over 14 distinct years, with a maximum of 3 publications in 2003 and 2005 and 2009 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2003	1	2	3
2005	1	2	3
2008	0	1	1
2009	2	1	3
2010	0	1	1
2012	1	0	1
2016	0	1	1
2018	1	0	1
2019	0	2	2
2021	2	1	3
2022	0	1	1
2023	0	1	1
2024	1	0	1

Below are the most recent publications written about "Troponin I" by people in Profiles.

Coats CJ, Masri A, Barriales-Villa R, Abraham TP, Brinkley DM, Claggett BL, Hagege A, Hegde SM, Ho CY, Kulac IJ, Lee MMY, Maron MS, Olivotto I, Owens AT, Solomon SD, Tfelt-Hansen J, Watkins H, Jacoby DL, Heitner SB, Kupfer S, Malik FI, Meng L, Wohltman A, Januzzi JL. Cardiac biomarkers and effects of aficamten in obstructive hypertrophic cardiomyopathy: the SEQUOIA-HCM trial. Eur Heart J. 2024 Nov 08; 45(42):4464-4478.

View in: PubMed
Belanger MJ, Kovell LC, Turkson-Ocran RA, Mukamal KJ, Liu X, Appel LJ, Miller ER, Sacks FM, Christenson RH, Rebuck H, Chang AR, Juraschek SP. Effects of the Dietary Approaches to Stop Hypertension Diet on Change in Cardiac Biomarkers Over Time: Results From the DASH-Sodium Trial. J Am Heart Assoc. 2023 01 17; 12(2):e026684.

View in: PubMed
Haimovitz D, Vereb M, Freeman L, Goldberg R, Lessard D, Rush J, Adin D. Effect of diet change in healthy dogs with subclinical cardiac biomarker or echocardiographic abnormalities. J Vet Intern Med. 2022 May; 36(3):1057-1065.

View in: PubMed
Garcia MA, Rucci JM, Thai KK, Lu Y, Kipnis P, Go AS, Desai M, Bosch NA, Martinez A, Clancy H, Devis Y, Myers LC, Liu VX, Walkey AJ. Association between Troponin I Levels during Sepsis and Postsepsis Cardiovascular Complications. Am J Respir Crit Care Med. 2021 09 01; 204(5):557-565.

View in: PubMed
Juraschek SP, Kovell LC, Appel LJ, Miller ER, Sacks FM, Chang AR, Christenson RH, Rebuck H, Mukamal KJ. Effects of Diet and Sodium Reduction on Cardiac Injury, Strain, and Inflammation: The DASH-Sodium Trial. J Am Coll Cardiol. 2021 06 01; 77(21):2625-2634.

View in: PubMed
Bang V, Ganatra S, Shah SP, Dani SS, Neilan TG, Thavendiranathan P, Resnic FS, Piemonte TC, Barac A, Patel R, Sharma A, Parikh R, Chaudhry GM, Vesely M, Hayek SS, Leja M, Venesy D, Patten R, Lenihan D, Nohria A, Cooper LT. Management of Patients With Giant Cell Myocarditis: JACC Review Topic of the Week. J Am Coll Cardiol. 2021 03 02; 77(8):1122-1134.

View in: PubMed
Mercado-Lubo R, Yarzebski J, Lessard D, Gore J, Goldberg RJ. Changing Trends in the Landscape of Patients Hospitalized With Acute Myocardial Infarction (2001 to 2011) (from the Worcester Heart Attack Study). Am J Cardiol. 2020 03 01; 125(5):673-677.

View in: PubMed
Gibbons PW, Goldberg RJ, Muehlschlegel S. A pilot study evaluating a simple cardiac dysfunction score to predict complications and survival among critically-ill patients with traumatic brain injury. J Crit Care. 2019 12; 54:130-135.

View in: PubMed
Adamson PD, Anderson JA, Brook RD, Calverley PMA, Celli BR, Cowans NJ, Crim C, Dixon IJ, Martinez FJ, Newby DE, Vestbo J, Yates JC, Mills NL. Cardiac Troponin I and Cardiovascular Risk in Patients With Chronic Obstructive Pulmonary?Disease. J Am Coll Cardiol. 2018 09 04; 72(10):1126-1137.

View in: PubMed
Burrell AJ, Kaye DM, Fitzgerald MC, Cooper DJ, Hare JL, Costello BT, Taylor AJ. Cardiac magnetic resonance imaging in suspected blunt cardiac injury: A prospective, pilot, cohort study. Injury. 2017 May; 48(5):1013-1019.

View in: PubMed

People

Explore

Similar Concepts

Top Journals