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Mark Epshtein PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentRadiology
AddressUmass Chan Medical School
55 Lake Ave N
Worcester MA 01655-0002
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentRadiology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Epshtein M, Mekler T, Shazeeb MS, Lindsay C, Gounis MJ, Korin N, Anagnostakou V. High-resolution 3D flow reconstruction of cerebrospinal fluid microcirculation using physics-informed neural network: Conceptualization and application to a large animal model. Comput Methods Programs Biomed. 2026 Aug 15; 283:109405. PMID: 42114465.
      Citations:    
    2. Kern AY, Charle L, Kreinin Y, Epshtein M, Spieker CJ, Chakf? N, Z?vodszky G, Pop R, Korin N, Mangin PH. Stent Thrombogenicity is Modulated by Design: Wire Crossings in Braided Stents are Focal Thrombogenic Niches. Thromb Haemost. 2026 Apr 09. PMID: 41956384.
      Citations:    
    3. Khoury M, Mekler T, Epshtein M, Kreinin Y, Korneyev D, Abezgauz L, Anagnostakou V, Ramon GZ, Sznitman J, Gounis M, Korin N. Isolation and focal treatment of brain aneurysms using interfacial fluid trapping. Sci Adv. 2024 10 04; 10(40):eadp4579. PMID: 39365869.
      Citations:    
    4. Kreinin Y, Epshtein M, Bolotin G, Korin N. Taking inspiration from birds to improve flow in prosthetic heart valves: an European Research Council granted project. Eur Heart J. 2024 Sep 01; 45(33):3012-3015. PMID: 38984412.
      Citations:    
    5. Benatti HR, Anagnostakou V, Taghian T, Hall EF, Nath S, Heilman CB, Beneduce BM, Leporati A, Raskett C, Epshtein M, King R, Gounis MJ, Malek AM, Gray-Edwards HL. A minimally invasive endovascular approach to the cerebellopontine angle cistern enables broad CNS biodistribution of scAAV9-CB-GFP. Mol Ther. 2024 10 02; 32(10):3346-3355. PMID: 39192584.
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    6. King RM, Anagnostakou V, Shazeeb MS, Hornibrook S, Mitchell J, Epshtein M, Raskett C, Henninger N, Puri AS, Merrill TL, Gounis MJ. Selective brain cooling with a novel catheter reduces infarct growth after recanalization in a canine large vessel occlusion model. Interv Neuroradiol. 2024 Jul 23; 15910199241266010. PMID: 39043215.
      Citations:    
    7. Anagnostakou V, Toth D, Bertalan G, M?ller S, Reimann RR, Epshtein M, Madjidyar J, Thurner P, Schubert T, Wegener S, Kulcsar Z. Dynamic Perviousness Has Predictive Value for Clot Fibrin Content in Acute Ischemic Stroke. Diagnostics (Basel). 2024 Jun 29; 14(13). PMID: 39001277.
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    8. Epshtein M, Gounis MJ, Bogdanov AA. X-ray Attenuating Vesicles with Neutrophil Extracellular Trap (NET) Specificity: Synthesis and Testing in a Model System. ACS Omega. 2024 Jul 09; 9(27):29391-29400. PMID: 39005803.
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    9. King RM, Peker A, Epshtein M, Arends JM, Brochu AB, Raskett CM, Slazas KJ, Puri AS, Arthur AS, Fiorella D, Gounis MJ, Anagnostakou V. Active drug-coated flow diverter in a preclinical model of intracranial stenting. J Neurointerv Surg. 2024 Jun 17; 16(7):731-736. PMID: 37399337.
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    10. Zoppo CT, Epshtein M, Gounis MJ, Anagnostakou V, King RM. Longitudinal healing flow diverting stents with phosphorylcholine surface modification. J Neurointerv Surg. 2024 May 21; 16(6):582-586. PMID: 37402572.
      Citations:    Fields:    
    11. Pereira VM, Lylyk P, Cancelliere N, Lylyk PN, Lylyk I, Anagnostakou V, Bleise C, Nishi H, Epshtein M, King RM, Shazeeb MS, Puri AS, Liang CW, Hanel RA, Spears J, Marotta TR, Lopes DK, Gounis MJ, Ughi GJ. Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe. Sci Transl Med. 2024 05 15; 16(747):eadl4497. PMID: 38748771.
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    12. Skarbek C, Anagnostakou V, Procopio E, Epshtein M, Raskett CM, Romagnoli R, Iviglia G, Morra M, Antonucci M, Nicoletti A, Caligiuri G, Gounis MJ. Development of a clot-adhesive coating to improve the performance of thrombectomy devices. J Neurointerv Surg. 2023 Dec; 15(12):1207-1211. PMID: 36878688.
      Citations:    Fields:    Translation:Humans
    13. Epshtein M, Shazeeb MS, K?hn AL, Anagnostakou V, Raskett CM, King RM, Goyal M, Mendes Pereira V, Arthur AS, Puri AS, Fiorella D, Gounis MJ. Development of an in-vitro model based on patient vessel geometry for simulated use testing in neurointerventional surgery. Interv Neuroradiol. 2025 Apr; 31(2):201-207. PMID: 36872879.
      Citations:    Fields:    
    14. Zohar B, Debbi L, Machour M, Nachum N, Redenski I, Epshtein M, Korin N, Levenberg S. A micro-channel array in a tissue engineered vessel graft guides vascular morphogenesis for anastomosis with self-assembled vascular networks. Acta Biomater. 2023 06; 163:182-193. PMID: 35597433.
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    15. Anagnostakou V, Epshtein M, Ughi GJ, King RM, Valavanis A, Puri AS, Gounis MJ. Transvascular in vivo microscopy of the subarachnoid space. J Neurointerv Surg. 2022 May; 14(5). PMID: 35115394.
      Citations: 1     Fields:    Translation:HumansAnimals
    16. Anagnostakou V, Epshtein M, K?hn AL, King RM, Puri A, Gounis MJ. Preclinical modeling of mechanical thrombectomy. J Biomech. 2022 01; 130:110894. PMID: 34915309.
      Citations:    Fields:    Translation:HumansAnimals
    17. Epshtein M, Levi M, Kraitem AM, Zidan H, King RM, Gawaz M, Gounis MJ, Korin N. Biophysical targeting of high-risk cerebral aneurysms. Bioeng Transl Med. 2022 Jan; 7(1):e10251. PMID: 35079628.
      Citations:    
    18. Szklanny AA, Machour M, Redenski I, Chochola V, Goldfracht I, Kaplan B, Epshtein M, Simaan Yameen H, Merdler U, Feinberg A, Seliktar D, Korin N, Jaro? J, Levenberg S. 3D Bioprinting of Engineered Tissue Flaps with Hierarchical Vessel Networks (VesselNet) for Direct Host-To-Implant Perfusion. Adv Mater. 2021 Oct; 33(42):e2102661. PMID: 34510579.
      Citations:    
    19. Rauti R, Ess A, Roi BL, Kreinin Y, Epshtein M, Korin N, Maoz BM. Transforming a well into a chip: A modular 3D-printed microfluidic chip. APL Bioeng. 2021 Jun; 5(2):026103. PMID: 33948527.
      Citations:    
    20. Khoury M, Epshtein M, Korin N. In Vitro 3D Cell-Cultured Arterial Models for Studying Vascular Drug Targeting Under Flow. J Vis Exp. 2021 03 14; (169). PMID: 33779620.
      Citations:    
    21. Asaad Y, Epshtein M, Korin N. A converging artery-sized model for shear adhesion mapping of particles. J Biomech. 2021 04 15; 119:110305. PMID: 33631661.
      Citations:    
    22. Epshtein M, Korin N. Computational and experimental investigation of particulate matter deposition in cerebral side aneurysms. J R Soc Interface. 2020 08; 17(169):20200510. PMID: 32811296.
      Citations:    
    23. Levi M, Epshtein M, Castor T, Gawaz M, Korin N. Glycoprotein VI (GPVI)-functionalized nanoparticles targeting arterial injury sites under physiological flow. Nanomedicine. 2020 10; 29:102274. PMID: 32712174.
      Citations:    
    24. Nemcovsky Amar D, Epshtein M, Korin N. Endothelial Cell Activation in an Embolic Ischemia-Reperfusion Injury Microfluidic Model. Micromachines (Basel). 2019 Dec 06; 10(12). PMID: 31817733.
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    25. Khoury M, Epshtein M, Zidan H, Zukerman H, Korin N. Mapping deposition of particles in reconstructed models of human arteries. J Control Release. 2020 02; 318:78-85. PMID: 31812540.
      Citations:    
    26. Asaad Y, Epshtein M, Yee A, Korin N. The Flow Dependent Adhesion of von Willebrand Factor (VWF)-A1 Functionalized Nanoparticles in an in Vitro Coronary Stenosis Model. Molecules. 2019 Jul 24; 24(15). PMID: 31344782.
      Citations:    
    27. Zohar B, Blinder Y, Epshtein M, Szklanny AA, Kaplan B, Korin N, Mooney DJ, Levenberg S. Multi-flow channel bioreactor enables real-time monitoring of cellular dynamics in 3D engineered tissue. Commun Biol. 2019; 2:158. PMID: 31069267.
      Citations:    
    28. Epshtein M, Korin N. Mapping the Transport Kinetics of Molecules and Particles in Idealized Intracranial Side Aneurysms. Sci Rep. 2018 06 04; 8(1):8528. PMID: 29867118.
      Citations:    
    29. Epshtein M, Korin N. Shear targeted drug delivery to stenotic blood vessels. J Biomech. 2017 01 04; 50:217-221. PMID: 27863741.
      Citations:    
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