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Vania (Vaia) Anagnostakou MD, MS, PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentRadiology
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
Phone508-856-1096
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentRadiology
    DivisionNeurointerventional Radiology


    Collapse Biography 
    Collapse education and training
    National and Kapodistrian University of Athens Medical School, Athens, , GreeceMSInterventional Radiology
    National and Kapodistrian University of Athens Medical School, Athens, , GreeceMD
    National and Kapodistrian University of Athens Medical School, Athens, , GreecePHDCardiology/Cardiopulmonary Reh
    Panhellenic Medical Association, Athens, GreeceBoard Certification RadiologyTitle of Medical Specialty
    Swiss Medical Association SWIF-FMH, Zurich, SwitzerlandBoard Certification/ FMHTitle of Diagnostic Neuroradiology
    Swiss Medical Association SWIF-FMH, Zurich, SwitzerlandBoard Certification/ FMHTitle of Interventional Neuroradiology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fiehler J, Ortega-Gutierrez S, Anagnostakou V, Cortese J, Cekirge HS, Fiorella D, Hanel R, Kulcsar Z, Lamin S, Liu J, Lylyk P, Marden FA, Pereira VM, Psychogios MN, Rice H, Rouchaud A, Saatci I, Siddiqui AH, Spelle L, Yang P, Grams A, Gounis MJ. Evaluation of flow diverters for cerebral aneurysm therapy: recommendations for imaging analyses in clinical studies, endorsed by ESMINT, ESNR, OCIN, SILAN, SNIS, and WFITN. J Neurointerv Surg. 2025 May 22; 17(6):632-639. PMID: 38830670.
      Citations:    
    2. Bertalan G, Thurner P, Madjidyar J, Krepuska M, Anagnostakou V, Kyselyova A, Schubert T, Kulcsar Z. Thrombus perviousness in acute ischemic stroke: a scoping review of methodology, predictive value, and future perspectives. Neuroradiology. 2025 May; 67(5):1121-1137. PMID: 40272464.
      Citations:    
    3. Sanchez S, Mossa-Basha M, Anagnostakou V, Liebeskind DS, Samaniego EA. Comprehensive imaging analysis of intracranial atherosclerosis. J Neurointerv Surg. 2025 Feb 14; 17(3):311-320. PMID: 38719445.
      Citations:    
    4. Khoury M, Mekler T, Epshtein M, Kreinin Y, Korneyev D, Abezgauz L, Anagnostakou V, Ramon GZ, Sznitman J, Gounis M, Korin N. Isolation and focal treatment of brain aneurysms using interfacial fluid trapping. Sci Adv. 2024 Oct 04; 10(40):eadp4579. PMID: 39365869.
      Citations:    
    5. Benatti HR, Anagnostakou V, Taghian T, Hall EF, Nath S, Heilman CB, Beneduce BM, Leporati A, Raskett C, Epshtein M, King R, Gounis MJ, Malek AM, Gray-Edwards HL. A minimally invasive endovascular approach to the cerebellopontine angle cistern enables broad CNS biodistribution of scAAV9-CB-GFP. Mol Ther. 2024 Oct 02; 32(10):3346-3355. PMID: 39192584.
      Citations:    
    6. Zoppo CT, Kolstad JW, King RM, Wolfe T, Kraitem A, Vardar Z, Badruddin A, Pereira E, Guerrero BP, Rosqueta AS, Ughi GJ, Gounis MJ, Zaidat OO, Anagnostakou V. A novel intrasaccular aneurysm device with high complete occlusion rate: initial results in a rabbit model. J Neurointerv Surg. 2024 Aug 14; 16(9):928-933. PMID: 37527927.
      Citations:    Fields:    
    7. King RM, Anagnostakou V, Shazeeb MS, Hornibrook S, Mitchell J, Epshtein M, Raskett C, Henninger N, Puri AS, Merrill TL, Gounis MJ. Selective brain cooling with a novel catheter reduces infarct growth after recanalization in a canine large vessel occlusion model. Interv Neuroradiol. 2024 Jul 23; 15910199241266010. PMID: 39043215.
      Citations:    
    8. Anagnostakou V, Toth D, Bertalan G, M?ller S, Reimann RR, Epshtein M, Madjidyar J, Thurner P, Schubert T, Wegener S, Kulcsar Z. Dynamic Perviousness Has Predictive Value for Clot Fibrin Content in Acute Ischemic Stroke. Diagnostics (Basel). 2024 Jun 29; 14(13). PMID: 39001277.
      Citations:    
    9. King RM, Peker A, Epshtein M, Arends JM, Brochu AB, Raskett CM, Slazas KJ, Puri AS, Arthur AS, Fiorella D, Gounis MJ, Anagnostakou V. Active drug-coated flow diverter in a preclinical model of intracranial stenting. J Neurointerv Surg. 2024 Jun 17; 16(7):731-736. PMID: 37399337.
      Citations:    Fields:    
    10. Zoppo CT, Epshtein M, Gounis MJ, Anagnostakou V, King RM. Longitudinal healing flow diverting stents with phosphorylcholine surface modification. J Neurointerv Surg. 2024 May 21; 16(6):582-586. PMID: 37402572.
      Citations:    Fields:    
    11. Pereira VM, Lylyk P, Cancelliere N, Lylyk PN, Lylyk I, Anagnostakou V, Bleise C, Nishi H, Epshtein M, King RM, Shazeeb MS, Puri AS, Liang CW, Hanel RA, Spears J, Marotta TR, Lopes DK, Gounis MJ, Ughi GJ. Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe. Sci Transl Med. 2024 05 15; 16(747):eadl4497. PMID: 38748771.
      Citations:    
    12. Shazeeb MS, Moholkar V, King RM, Vedantham S, Vardar Z, Kraitem A, Lindsay C, Anagnostakou V, Singh J, Massari F, de Macedo Rodrigues K, Naragum V, Puri AS, Carniato S, Gounis MJ, K?hn AL. Assessment of thrombectomy procedure difficulty by neurointerventionalists based on vessel geometry parameters from carotid artery 3D reconstructions. J Clin Neurosci. 2023 Jul; 113:121-125. PMID: 37262981.
      Citations:    Fields:    Translation:Humans
    13. Skarbek C, Anagnostakou V, Procopio E, Epshtein M, Raskett CM, Romagnoli R, Iviglia G, Morra M, Antonucci M, Nicoletti A, Caligiuri G, Gounis MJ. Development of a clot-adhesive coating to improve the performance of thrombectomy devices. J Neurointerv Surg. 2023 Dec; 15(12):1207-1211. PMID: 36878688.
      Citations:    Fields:    Translation:Humans
    14. Epshtein M, Shazeeb MS, K?hn AL, Anagnostakou V, Raskett CM, King RM, Goyal M, Mendes Pereira V, Arthur AS, Puri AS, Fiorella D, Gounis MJ. Development of an in-vitro model based on patient vessel geometry for simulated use testing in neurointerventional surgery. Interv Neuroradiol. 2025 Apr; 31(2):201-207. PMID: 36872879.
      Citations:    Fields:    
    15. Thomson BR, Richter H, Akeret K, Buzzi RM, Anagnostakou V, van Niftrik CHB, Schwendinger N, Kulcsar Z, Kronen PW, Regli L, Fierstra J, Schaer DJ, Hugelshofer M. Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity. J Stroke Cerebrovasc Dis. 2023 Mar; 32(3):106985. PMID: 36640721.
      Citations:    
    16. Anagnostakou V, King RM, Gutierrez L, Black JD, Lee J, Virmani R, Puri AS, Siddiqui AH, Gounis MJ. Preclinical model of anterior circulation intracranial stenting. J Neurointerv Surg. 2023 Nov; 15(11):1148-1154. PMID: 36609543.
      Citations:    Fields:    
    17. King RM, Peker A, Anagnostakou V, Raskett CM, Arends JM, Dixit HG, Ughi GJ, Puri AS, Gounis MJ, Shazeeb MS. High-frequency optical coherence tomography predictors of aneurysm occlusion following flow diverter treatment in a preclinical model. J Neurointerv Surg. 2023 Sep; 15(9):919-923. PMID: 36002288.
      Citations: 1     Fields:    Translation:Animals
    18. Kuhn AL, Singh J, Anagnostakou V, Massari F, Gounis MJ, Puri AS. Dawn of a New Era: Super Large-Bore Aspiration Catheters for Complete Clot Ingestion During Thrombectomy for Large-Vessel Occlusions. World Neurosurg. 2022 11; 167:5-6. PMID: 36108362.
      Citations:    Fields:    Translation:Humans
    19. Massari F, Dabus G, Cortez GM, Singh J, Kuhn AL, Naragum V, Anagnostakou V, Hanel RA, Gounis MJ, Puri AS. Super large-bore ingestion of clot (SLIC) leads to high first pass effect in thrombectomy for large vessel occlusion. J Neurointerv Surg. 2023 Jul; 15(7):664-668. PMID: 35732483.
      Citations:    Fields:    Translation:Humans
    20. Shazeeb MS, King RM, Anagnostakou V, Vardar Z, Kraitem A, Kolstad J, Raskett C, Le Moan N, Winger JA, Kelly L, Krtolica A, Henninger N, Gounis MJ. Novel Oxygen Carrier Slows Infarct Growth in Large Vessel Occlusion Dog Model Based on Magnetic Resonance Imaging Analysis. Stroke. 2022 04; 53(4):1363-1372. PMID: 35306836.
      Citations: 1     Fields:    Translation:HumansAnimals
    21. Anagnostakou V, Epshtein M, Ughi GJ, King RM, Valavanis A, Puri AS, Gounis MJ. Transvascular in vivo microscopy of the subarachnoid space. J Neurointerv Surg. 2022 May; 14(5). PMID: 35115394.
      Citations: 1     Fields:    Translation:HumansAnimals
    22. Anagnostakou V, Epshtein M, K?hn AL, King RM, Puri A, Gounis MJ. Preclinical modeling of mechanical thrombectomy. J Biomech. 2022 01; 130:110894. PMID: 34915309.
      Citations:    Fields:    Translation:HumansAnimals
    23. Anagnostakou V, Ughi GJ, Puri AS, Gounis MJ. Optical Coherence Tomography for Neurovascular Disorders. Neuroscience. 2021 10 15; 474:134-144. PMID: 34126186.
      Citations: 1     Fields:    Translation:Humans
    24. Machi P, Luft A, Winklhofer S, Anagnostakou V, Kulcs?r Z. Endovascular treatment of acute ischemic stroke. J Neurosurg Sci. 2021 Jun; 65(3):259-268. PMID: 33245221.
      Citations: 1     Fields:    Translation:Humans
    25. Chueh JY, Marosfoi MG, Anagnostakou V, Arslanian RA, Marks MP, Gounis MJ. Quantitative Characterization of Recanalization and Distal Emboli with a Novel Thrombectomy Device. Cardiovasc Intervent Radiol. 2021 Feb; 44(2):318-324. PMID: 33179161.
      Citations: 1     Fields:    Translation:Humans
    26. Vargas J, Blalock J, Venkatraman A, Anagnostakou V, King RM, Ewing JA, Gounis MJ, Turner RD, Chaudry I, Turk A. Efficacy of beveled tip aspiration catheter in mechanical thrombectomy for acute ischemic stroke. J Neurointerv Surg. 2021 Sep; 13(9):823-826. PMID: 33024028.
      Citations:    Fields:    Translation:Humans
    27. Vardar Z, King RM, Kraitem A, Langan ET, Peterson LM, Duncan BH, Raskett CM, Anagnostakou V, Gounis MJ, Puri AS, Ughi GJ. High-resolution image-guided WEB aneurysm embolization by high-frequency optical coherence tomography. J Neurointerv Surg. 2021 Jul; 13(7):669-673. PMID: 32989033.
      Citations: 5     Fields:    Translation:Animals
    28. Kadooka K, Anagnostakou V, Bozinov O, Kulcs?r Z. Delayed mesencephalic venous infarction after endovascular treatment of a giant aneurysm of the posterior cerebral artery: Case report and anatomical review. Interv Neuroradiol. 2020 Oct; 26(5):593-597. PMID: 32873105.
      Citations:    Fields:    Translation:Humans
    29. Hainc N, Mannil M, Anagnostakou V, Alkadhi H, Bl?thgen C, Wacht L, Bink A, Husain S, Kulcs?r Z, Winklhofer S. Deep learning based detection of intracranial aneurysms on digital subtraction angiography: A feasibility study. Neuroradiol J. 2020 Aug; 33(4):311-317. PMID: 32633602.
      Citations: 13     Fields:    Translation:Humans
    30. K?hn AL, Vardar Z, Kraitem A, King RM, Anagnostakou V, Puri AS, Gounis MJ. Biomechanics and hemodynamics of stent-retrievers. J Cereb Blood Flow Metab. 2020 12; 40(12):2350-2365. PMID: 32428424.
      Citations: 1     Fields:    Translation:Humans
    31. Hugelshofer M, Buzzi RM, Schaer CA, Richter H, Akeret K, Anagnostakou V, Mahmoudi L, Vaccani R, Vallelian F, Deuel JW, Kronen PW, Kulcsar Z, Regli L, Baek JH, Pires IS, Palmer AF, Dennler M, Humar R, Buehler PW, Kircher PR, Keller E, Schaer DJ. Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm. J Clin Invest. 2019 12 02; 129(12):5219-5235. PMID: 31454333.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    32. Kadooka K, Hagenbuch N, Anagnostakou V, Valavanis A, Kulcs?r Z. Safety and efficacy of balloon angioplasty in symptomatic intracranial stenosis: A systematic review and meta-analysis. J Neuroradiol. 2020 Feb; 47(1):27-32. PMID: 30862462.
      Citations: 7     Fields:    Translation:Humans
    33. Sivrioglu AK, Saglam M, Yildiz B, Anagnostakou V, Kizilkilic O. Ivy Sign in Moyamoya Disease. Eurasian J Med. 2016 Feb; 48(1):58-61. PMID: 27026766.
      Citations:    
    34. Saglam M, Kizilkili? O, Anagnostakou V, Yildiz B, Ko?er N, Islak C. Geometrical characteristics after Y-stenting of the basilar bifurcation. Diagn Interv Radiol. 2015 Nov-Dec; 21(6):483-7. PMID: 26359879.
      Citations: 7     Fields:    Translation:Humans
    35. Saglam M, Anagnostakou V, Kocer N, Islak C, Kizilkilic O. Teaching NeuroImages: A rare cause of trigeminal neuralgia: dysplastic venous aneurysm of dural arteriovenous fistula. Neurology. 2015 Apr 28; 84(17):e128-9. PMID: 25917490.
      Citations: 1     Fields:    Translation:Humans
    36. Kokotsakis J, Rouska EG, Harling L, Ashrafian H, Anagnostakou V, Charitos C, Athanasiou T. Right ventricular outflow tract obstruction caused by double-chambered right ventricle presenting in adulthood. Tex Heart Inst J. 2014 Aug; 41(4):425-8. PMID: 25120399.
      Citations: 3     Fields:    Translation:Humans
    37. Saglam M, Sarici A, Anagnostakou V, Yildiz B, Kocer N, Islak C, Kizilkilic O. An alternative technique of the superselective catheterization of the ophthalmic artery for intra-arterial chemotherapy of the retinoblastoma: retrograde approach through the posterior communicating artery to the ophthalmic artery. Neuroradiology. 2014 Sep; 56(9):751-4. PMID: 24913287.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    38. Soylu E, Harling L, Ashrafian H, Anagnostakou V, Tassopoulos D, Charitos C, Kokotsakis J, Athanasiou T. Surgical treatment of innominate artery and aortic aneurysm: a case report and review of the literature. J Cardiothorac Surg. 2013 Jun 01; 8:141. PMID: 23725538.
      Citations: 8     Fields:    Translation:Humans
    39. Kokotsakis I, Harling L, Anagnostakou V, Tassopoulos D, Charitos C, Ashrafian H, Athanasiou T. Single-stage surgical repair in a complex case of aberrant right subclavian artery aneurysm and common carotid trunk. J Cardiothorac Surg. 2013 Apr 25; 8:112. PMID: 23618166.
      Citations:    Fields:    Translation:Humans
    40. Dedeilias P, Koletsis E, Nenekidis I, Chatziioannou A, Tsipas P, Dimaka K, Anagnostakou V, Apostolakis E. Intimal aortic sarcoma mimicking ruptured thoracoabdominal type IV aneurysm. A rare case report and review of the literature. J Cardiothorac Surg. 2011 Dec 11; 6:162. PMID: 22152923.
      Citations: 4     Fields:    Translation:Humans
    41. Nenekidis I, Stathopoulos GT, Anagnostakou V, Kokkori A, Dedeilias P, Kokotsakis J, Argiriou M, Zisis C. Atypical pulmonary carcinoid tumour in a 28-year-old nonsmoker with Prader-Willi syndrome. Eur Respir J. 2011 Nov; 38(5):1230-3. PMID: 22045793.
      Citations: 9     Fields:    Translation:Humans
    42. Kokotsakis J, Nenekidis I, Anagnostakou V, Paralikas I, Giotopoulou A, Kratimenos T, Karameri V, Lioulias A. Papillary fibroelastoma of the aortic valve in a ?-thalassemia patient. Gen Thorac Cardiovasc Surg. 2011 Oct; 59(10):712-4. PMID: 21984141.
      Citations: 2     Fields:    Translation:Humans
    43. Nenekidis I, Anagnostakou V, Paralikas I, Kokkori A, Dedeilias P, Zisis C. Ectopic hepatocellular carcinomas developed in the chest wall and skull. Asian Cardiovasc Thorac Ann. 2011 Oct; 19(5):360-2. PMID: 22100934.
      Citations: 2     Fields:    Translation:Humans
    44. Dedeilias P, Nenekidis I, Koukis I, Anagnostakou V, Paparizou N, Zompolos S, Apostolakis E. Acute heart failure caused by a giant hepatocellular metastatic tumor of the right atrium. J Cardiothorac Surg. 2011 Aug 26; 6:102. PMID: 21867564.
      Citations: 5     Fields:    Translation:Humans
    45. Kokotsakis J, Anagnostakou V, Almpanis G, Paralikas I, Nenekidis I, Kratimenos T, Prapa E, Tragotsalou N, Lioulias A, Mazarakis A. Cor triatriatum presenting as heart failure with reduced ejection fraction: a case report. J Cardiothorac Surg. 2011 Jun 14; 6:83. PMID: 21672201.
      Citations: 4     Fields:    Translation:Humans
    46. Kokotsakis J, Anagnostakou V, Kratimenos T, Ashrafian H, Athanasiou T. Frozen Elephant Trunk: a technique which can be offered in complex pathology to fix the whole aorta in one setting. J Cardiothorac Surg. 2011 May 08; 6:66. PMID: 21548999.
      Citations: 2     Fields:    Translation:Humans
    47. Anagnostakou V, Nenekidis I, Ashrafian H, Kokotsakis J, Athanasiou T. Acute aortic syndrome: surgical, endovascular or medical treatment. Br J Hosp Med (Lond). 2011 May; 72(5):252-8. PMID: 21647039.
      Citations:    Fields:    Translation:Humans
    48. Anagnostakou V, Chatzimichail K, Dimopoulos S, Karatzanos E, Papazachou O, Tasoulis A, Anastasiou-Nana M, Roussos C, Nanas S. Effects of interval cycle training with or without strength training on vascular reactivity in heart failure patients. J Card Fail. 2011 Jul; 17(7):585-91. PMID: 21703531.
      Citations: 21     Fields:    Translation:Humans
    49. Nenekidis I, Anagnostakou V, Zisis C, Prokakis C, Koletsis EN, Apostolakis E, Dedeilias P. Transternal repair of a giant Morgagni hernia causing cardiac tamponade in a patient with coexisting severe aortic valve stenosis. J Cardiothorac Surg. 2011 Mar 14; 6:30. PMID: 21401951.
      Citations: 4     Fields:    Translation:Humans
    50. Anagnostakou V, Nenekidis I, Zisis C, Dedeilias P. Huge Kommerell's diverticulum associated with type-B aortic dissection. Eur J Cardiothorac Surg. 2011 Sep; 40(3):771. PMID: 21349734.
      Citations: 1     Fields:    Translation:Humans
    51. Sepehripour AH, Ahmed K, Vecht JA, Anagnostakou V, Suliman A, Ashrafian H, Darzi A, Athanasiou T. Management of the left subclavian artery during endovascular stent grafting for traumatic aortic injury - a systematic review. Eur J Vasc Endovasc Surg. 2011 Jun; 41(6):758-69. PMID: 21345700.
      Citations: 10     Fields:    Translation:Humans
    52. Kokotsakis J, Anagnostakou V, Nenekidis I, Lioulias A. Right aortic arch with mirror image aplasia of brachiocephalic trunk presented as subclavian steal syndrome. Eur J Cardiothorac Surg. 2011 Oct; 40(4):1029-30. PMID: 21316258.
      Citations: 1     Fields:    Translation:Humans
    53. Argiriou M, Paralikas I, Anagnostakou V, Panagiotakopoulos V, Argiriou O, Charitos C. Creating arteriovenous fistula using an automatic anastomotic device. J Vasc Surg. 2011 Feb; 53(2):531-3. PMID: 20875717.
      Citations:    Fields:    Translation:Humans
    54. Kokotsakis J, Misthos P, Sakellaridis T, Farsaris D, Anagnostakou V, Spiliotopoulos K, Lioulias A. Emergent endovascular repair as damage control step of aortic injury after posterior spinal instrumentation. Ann Thorac Surg. 2010 Apr; 89(4):1304. PMID: 20338369.
      Citations: 5     Fields:    Translation:Humans
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