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Lloyd Hutchinson PhD

TitleAssociate Professor
InstitutionUMass Chan Medical School
DepartmentPathology
AddressUMass Chan Medical School
One Innovation Drive Biotech Three
Worcester MA 01605
Phone508-793-6240
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentPathology
    DivisionAnatomic Pathology


    Collapse Biography 
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    McMaster University, Hamilton, ON, CanadaPHDMolecular Virology/Immunology

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    Academic Background:

    BS -1987, Microbiology and Chemistry, Univ. of Guelph, Guelph ON Canada

    PhD.- 1996, Molecular Virology and Immunology, McMaster Univ., Hamilton ON Canada

    Postdoctoral Fellow -2004, Molecular Oncology, Vascular Biology Program, Children’s Hospital, Harvard Medical School, Boston MA

    Research Interests :Dr. Hutchinson's picture

    My research encompasses tumor biology including hematopathology and solid tumors. A primary focus is the discovery and development of novel technology and cancer biomarkers for early cancer detection. The eventual goal is to provide oncologists with tools that enable early intervention and better outcomes for patients. Diagnostic assays and biomarkers in development may be used for early detection, to assist in diagnosis, prognosis, and treatment decisions or to monitor levels of minimal residual disease



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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cammann E, Madhav S, Hutchinson L, Cerny J, Ramanathan M, Bledsoe JR, Makarenko V, Patel SA, Meng X, Tomaszewicz K, Nath R, Chen B, Woda B, Selove W. Frameshift Mutations in Leukemia-Associated Genes Correlate With Superior Outcomes in Patients Undergoing Allogeneic Stem Cell Transplant for De Novo Acute Myeloid Leukemia. J Hematol. 2024 Jun; 13(3):86-93. PMID: 38993741.
      Citations:    
    2. Patel SA, Gerber WK, Zheng R, Khanna S, Hutchinson L, Abel GA, Cerny J, DaSilva BA, Zhang TY, Ramanathan M, Khedr S, Selove W, Woda B, Miron PM, Higgins AW, Gerber JM. Natural history of clonal haematopoiesis seen in real-world haematology settings. Br J Haematol. 2024 May; 204(5):1844-1855. PMID: 38522849.
      Citations:    
    3. Cornejo KM, Hutchinson L, O'Donnell P, Meng X, Tomaszewicz K, Shalin SC, Cassarino DS, Chan MP, Quinn TR, Googe PB, Nazarian RM. Molecular Profiling of Syringocystadenocarcinoma Papilliferum Reveals RAS-Activating Mutations. Arch Pathol Lab Med. 2024 Feb 01; 148(2):215-222. PMID: 37074845.
      Citations:    Fields:    Translation:Humans
    4. He X, Madhav S, Hutchinson L, Meng X, Fischer A, Dresser K, Yang M. Prevalence of Chlamydia infection detected by immunohistochemistry in patients with anorectal ulcer and granulation tissue. Hum Pathol. 2024 02; 144:8-14. PMID: 38159868.
      Citations:    Fields:    
    5. Patel SA, Cerny J, Gerber WK, Ramanathan M, Ediriwickrema A, Tanenbaum B, Hutchinson L, Meng X, Flahive J, Barton B, Gillis-Smith AJ, Suzuki S, Khedr S, Selove W, Higgins AW, Miron PM, Simin K, Woda B, Gerber JM. Prognostic heterogeneity and clonal dynamics within distinct subgroups of myelodysplastic syndrome and acute myeloid leukemia with TP53 disruptions. EJHaem. 2023 Nov; 4(4):1059-1070. PMID: 38024632.
      Citations:    
    6. Janardhan HP, Dresser K, Hutchinson L, Trivedi CM. Pathological MAPK activation-mediated lymphatic basement membrane disruption causes lymphangiectasia that is treatable with ravoxertinib. JCI Insight. 2022 09 08; 7(17). PMID: 36073544.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    7. Jung R, Janardhan HP, Dresser K, Cotton JL, Hutchinson L, Mao J, Trivedi CM. Response by Jung et al to Letter Regarding Article, "Sustained Activation of Endothelial YAP1 Causes Epithelioid Hemangioendothelioma". Arterioscler Thromb Vasc Biol. 2021 10; 41(10):e493-e495. PMID: 34550712.
      Citations:    Fields:    Translation:Humans
    8. Patel SA, Lloyd MR, Cerny J, Shi Q, Simin K, Ediriwickrema A, Hutchinson L, Miron PM, Higgins AW, Ramanathan M, Gerber JM. Clinico-genomic profiling and clonal dynamic modeling of TP53-aberrant myelodysplastic syndrome and acute myeloid leukemia. Leuk Lymphoma. 2021 12; 62(14):3348-3360. PMID: 34496723.
      Citations: 5     Fields:    Translation:Humans
    9. Selove W, Hutchinson L, Makarenko V, Meng X, Tomaszewicz K, Ramanathan M, Cerny J, Nath R, Chen B, Woda B, Bledsoe JR. Impact of pretransplant mutation status on survival after allogeneic stem cell transplant for acute myeloid leukemia. EJHaem. 2021 Aug; 2(3):514-519. PMID: 35844698.
      Citations:    
    10. Patel SA, Bledsoe JR, Higgins AW, Hutchinson L, Gerber JM. Rapid and Deep Remission Induced by Blinatumomab for CD19-Positive Chronic Myeloid Leukemia in Lymphoid Blast Phase. JCO Precis Oncol. 2021 07; 5. PMID: 34409243.
      Citations: 2     Fields:    Translation:Humans
    11. Jung R, Janardhan HP, Dresser K, Cotton JL, Hutchinson L, Mao J, Trivedi CM. Sustained Activation of Endothelial YAP1 Causes Epithelioid Hemangioendothelioma. Arterioscler Thromb Vasc Biol. 2021 07; 41(7):2233-2235. PMID: 34078092.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    12. Madahian S, Judelson R, Zhu X, Meng X, Dresser K, Hutchinson L, Bledsoe JR. CD56 expression in basaloid anal squamous cell carcinoma - A potential diagnostic pitfall. Ann Diagn Pathol. 2021 Aug; 53:151758. PMID: 33989959.
      Citations: 4     Fields:    Translation:HumansCells
    13. Sun T, Hutchinson L, Tomaszewicz K, Caporelli ML, Meng X, McCauley K, Fischer AH, Cosar EF, Cornejo KM. Diagnostic value of a comprehensive, urothelial carcinoma-specific next-generation sequencing panel in urine cytology and bladder tumor specimens. Cancer Cytopathol. 2021 07; 129(7):537-547. PMID: 33539671.
      Citations: 1     Fields:    Translation:Humans
    14. Zhu X, Jamshed S, Zou J, Azar A, Meng X, Bathini V, Dresser K, Strock C, Yalamarti B, Yang M, Tomaszewicz K, Tjionas G, Mochel MC, Hutchinson L, Bledsoe JR. Molecular and immunophenotypic characterization of anal squamous cell carcinoma reveals distinct clinicopathologic groups associated with HPV and TP53 mutation status. Mod Pathol. 2021 05; 34(5):1017-1030. PMID: 33483624.
      Citations: 9     Fields:    Translation:Humans
    15. Makarenko VV, Kandil D, Cosar EF, Hutchinson L, Khan A. Molecular analysis of a rare case of low-grade primary peritoneal serous carcinoma in a male. Rare Tumors. 2020; 12:2036361320979219. PMID: 33354307.
      Citations:    
    16. Bai S, Hutchinson L, Akalin A, Faquin W, Vaezi A, Fischer A. Multifocal or Metastatic B-RAF (V600E) Glomus Tumor in the Parotid and Neck: A Case Report Including Cytologic, Histologic, and Molecular Features. AJSP: Reviews & Reports. 2020; (6):310-313. View Publication.
    17. Harris T, Sheel A, Zong Y, Hutchinson LM, Cornejo KM, Bubendorf L, Yates J, Fischer AH. Cytologically targeted next-generation sequencing: a synergy for diagnosing urothelial carcinoma. J Am Soc Cytopathol. 2021 Jan-Feb; 10(1):94-102. PMID: 33184010.
      Citations: 2     Fields:    Translation:Humans
    18. Janardhan HP, Meng X, Dresser K, Hutchinson L, Trivedi CM. KRAS or BRAF mutations cause hepatic vascular cavernomas treatable with MAP2K-MAPK1 inhibition. J Exp Med. 2020 07 06; 217(7). PMID: 32405640.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    19. Khedr S., Enwereuzo C.L., Secola S., Mai N, Miron P, Hutchinson L and Chen B. Plasmablastic lymphoma presenting as a soft tissue mass associated with a chronic wound in an immunocompetent patient. J Hematopathology. 2020; (13):279–285. View Publication.
    20. Wang X, Resendes NM, Shanahan L, Hutchinson L, Woda B, Cerny J. Chronic neutrophilic leukemia, a rare case of leukocytosis. Leuk Res. 2020 07; 94:106384. PMID: 32447046.
      Citations: 2     Fields:    Translation:Humans
    21. Bai S, Hutchinson LM, Meng X, Bai H, Cosar EF, Khan A, Cornejo K. Dedifferentiated Carcinoma of the Endometrium Associated With Low-grade M?llerian Adenosarcoma: A Clinicopathologic Case Report Including the Immunohistochemical and Molecular Profile. Int J Gynecol Pathol. 2020 Mar; 39(2):141-145. PMID: 30908285.
      Citations: 1     Fields:    Translation:Humans
    22. Javvaji C, Bledsoe JR, Hutchinson L, Cosar EF, McIntosh LJ, Bathini VG. Metastatic Signet Ring Cell Carcinoma of the Ampulla of Vater with an Unusually Prolonged Survival. J Gastrointest Cancer. 2020 Mar; 51(1):354-358. PMID: 31456115.
      Citations: 1     Fields:    Translation:Humans
    23. Makarenko VV, Vaezi AE, Brettler DB, Hutchinson L, Woda BA, Chen BJ. Laryngeal mucous membrane plasmacytosis with 15 year follow-up: Case report and literature review. Leuk Res Rep. 2020; 13:100190. PMID: 31867207.
      Citations:    
    24. Sun T, Hutchinson L, Zhou AG, Liu Q, Cosar EF, St Cyr M, Ninteau N, Dresser K, Cheng L, Jiang Z, Cornejo KM. The Utility of ERBB4 and RB1 Immunohistochemistry in Distinguishing Chromophobe Renal Cell Carcinoma From Renal Oncocytoma. Int J Surg Pathol. 2020 May; 28(3):259-264. PMID: 31640438.
      Citations:    Fields:    Translation:Humans
    25. Sakhdari A, Moghaddam PA, Pejchal M, Cosar EF, Hutchinson L. Sequential molecular and cytologic analyses provides a complementary approach to the diagnosis of pancreatic cystic lesions: a decade of clinical practice. J Am Soc Cytopathol. 2020 Jan - Feb; 9(1):38-44. PMID: 31711852.
      Citations: 2     Fields:    Translation:Humans
    26. Cornejo KM, Cosar EF, Paner GP, Yang P, Tomaszewicz K, Meng X, Mehta V, Sirintrapun SJ, Barkan GA, Hutchinson L. Mutational Profile Using Next-Generation Sequencing May Aid in the Diagnosis and Treatment of Urachal Adenocarcinoma. Int J Surg Pathol. 2020 Feb; 28(1):51-59. PMID: 31496327.
      Citations: 4     Fields:    Translation:Humans
    27. Sakhdari A, Moghaddam PA, Ok CY, Walter O, Tomaszewicz K, Caporelli ML, Meng X, LaFemina J, Whalen G, Belkin E, Zivny J, Wassef W, Woda BA, Hutchinson LM, Cosar EF. Somatic molecular analysis augments cytologic evaluation of pancreatic cyst fluids as a diagnostic tool. Oncotarget. 2019 Jun 18; 10(40):4026-4037. PMID: 31258847.
      Citations: 4     Fields:    
    28. Ma L, Pak ML, Ou J, Yu J, St Louis P, Shan Y, Hutchinson L, Li S, Brehm MA, Zhu LJ, Green MR. Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells. Proc Natl Acad Sci U S A. 2019 05 21; 116(21):10482-10487. PMID: 31068472.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    29. Clark JL, Lee C, Kandil D, Hutchinson L, Khan A. Melanoma of the Breast with Smoothened (SMO) Mutation: Case Report and review of the Literature. Journal of Cancer Genetics and Biomarkers. 2019; 3(1):19-24. View Publication.
    30. Zhu X, Salhab M, Tomaszewicz K, Meng X, Mathew C, Bathini V, Switzer B, Walter O, Cosar EF, Wang X, Lambert LA, Hutchinson LM. Heterogeneous mutational profile and prognosis conferred by TP53 mutations in appendiceal mucinous neoplasms. Hum Pathol. 2019 03; 85:260-269. PMID: 30458197.
      Citations: 3     Fields:    Translation:Humans
    31. Zhu S, Ward BM, Yu J, Matthew-Onabanjo AN, Janusis J, Hsieh CC, Tomaszewicz K, Hutchinson L, Zhu LJ, Kandil D, Shaw LM. IRS2 mutations linked to invasion in pleomorphic invasive lobular carcinoma. JCI Insight. 2018 04 19; 3(8). PMID: 29669935.
      Citations: 11     Fields:    Translation:Humans
    32. Liu Q, Cornejo KM, Cheng L, Hutchinson L, Wang M, Zhang S, Tomaszewicz K, Cosar EF, Woda BA, Jiang Z. Next-Generation Sequencing to Detect Deletion of RB1 and ERBB4 Genes in Chromophobe Renal Cell Carcinoma: A Potential Role in Distinguishing Chromophobe Renal Cell Carcinoma from Renal Oncocytoma. Am J Pathol. 2018 04; 188(4):846-852. PMID: 29353061.
      Citations: 6     Fields:    Translation:Humans
    33. Sakhdari A, Hutchinson L, Vaskas N, Scott M, Cosar EF, Al-Turkmani R. Routine Analysis of Lipase in Cyst Fluid Is Unnecessary and Does Not Help Discriminate Between Nonneoplastic and Neoplastic Cystic Pancreatic Lesions. Pancreas. 2017 Mar; 46(3):e25-e27. PMID: 28187114.
      Citations:    Fields:    Translation:Humans
    34. Ahmadi Moghaddam P, Cornejo KM, Hutchinson L, Tomaszewicz K, Dresser K, Deng A, O'Donnell P. Complete Spontaneous Regression of Merkel Cell Carcinoma After Biopsy: A Case Report and Review of the Literature. Am J Dermatopathol. 2016 Nov; 38(11):e154-e158. PMID: 27759689.
      Citations: 11     Fields:    Translation:HumansCells
    35. Magotra M, Sakhdari A, Lee PJ, Tomaszewicz K, Dresser K, Hutchinson LM, Woda BA, Chen BJ. Immunohistochemical loss of 5-hydroxymethylcytosine expression in acute myeloid leukaemia: relationship to somatic gene mutations affecting epigenetic pathways. Histopathology. 2016 Dec; 69(6):1055-1065. PMID: 27458708.
      Citations: 5     Fields:    Translation:Humans
    36. Fischer AH, Hutchinson LM. Technical and US regulatory issues in triaging material for the molecular laboratory. Cancer Cytopathol. 2017 02; 125(2):83-90. PMID: 27598019.
      Citations: 1     Fields:    Translation:Humans
    37. Cornejo KM, Hutchinson L, Meng X, O'Donnell P, Deng A. Endocrine Mucin-Producing Sweat Gland Carcinoma of the Eyelid: A Report of a Case With Molecular Analysis. Am J Dermatopathol. 2016 Aug; 38(8):636-8. PMID: 26675355.
      Citations: 5     Fields:    Translation:Humans
    38. Liu Q, Tomaszewicz K, Hutchinson L, Hornick JL, Woda B, Yu H. Somatic mutations in histiocytic sarcoma identified by next generation sequencing. Virchows Arch. 2016 Aug; 469(2):233-41. PMID: 27259537.
      Citations: 22     Fields:    Translation:Humans
    39. Zhou AG, Liu Y, Cyr MS, Garver J, Woda BA, Cosar EF, Hutchinson LM. Role of Tetrasomy for the Diagnosis of Urothelial Carcinoma Using UroVysion Fluorescent In Situ Hybridization. Arch Pathol Lab Med. 2016 Jun; 140(6):552-9. PMID: 27232347.
      Citations: 2     Fields:    Translation:Humans
    40. Kamionek M, Ahmadi Moghaddam P, Sakhdari A, Kovach AE, Welch M, Meng X, Dresser K, Tomaszewicz K, Cosar EF, Mark EJ, Fraire AE, Hutchinson L. Mutually exclusive extracellular signal-regulated kinase pathway mutations are present in different stages of multi-focal pulmonary Langerhans cell histiocytosis supporting clonal nature of the disease. Histopathology. 2016 Sep; 69(3):499-509. PMID: 26915300.
      Citations: 17     Fields:    Translation:HumansCells
    41. Fang M, Hutchinson L, Deng A, Green MR. Common BRAF(V600E)-directed pathway mediates widespread epigenetic silencing in colorectal cancer and melanoma. Proc Natl Acad Sci U S A. 2016 Feb 02; 113(5):1250-5. PMID: 26787892.
      Citations: 33     Fields:    Translation:HumansCells
    42. Cornejo KM, Hutchinson L, Cyr MS, Nose V, McLaughlin PJ, Iafrate AJ, Sadow PM. MYC Analysis by Fluorescent In Situ Hybridization and Immunohistochemistry in Primary Adrenal Angiosarcoma (PAA): a Series of Four Cases. Endocr Pathol. 2015 Dec; 26(4):334-41. PMID: 26223194.
      Citations: 5     Fields:    Translation:Humans
    43. Zhou AG, Hutchinson L, Cosar EF. 2015. Ancillary Tests for the Detection of Urothelial Carcinoma. In Xiaoqi Lin, Longwen Chen, Ritu Nayar, editors. Cytology, Histology, Cystoscopy, and Radiology of the Urinary System Atlas and Practical Guide. Peoples Medical Publishing House-USA. ISBN 978-1-60795-185-8. 2015.
    44. Sakhdari A, Hutchinson L, Cosar EF. 2015. Chapter 7: Molecular Pathology of Lobular Carcinoma. Chapter 9: Molecular Pathology of HER Family of Oncogenes in Breast Cancer: HER-2. Evaluation and Role in Targeted Therapy. Chapter 19: Specimens for Molecular Testing in Breast Cancer . In Ashraf Khan, Ian O. Ellis, Andrew M. Hanby, Ediz F. Cosar, Emad A. Rakha, Dina Kandil, editors. Molecular Pathology Library, Volume 10. Precision Molecular Pathology of Breast Cancer. Springer, New York, p. 95,119,317. DOI: http://dx.doi.org/10.1007/978-1-4939-2886-6. 2015. View Publication.
    45. Cornejo KM, Deng A, Wu H, Cosar EF, Khan A, St Cyr M, Tomaszewicz K, Dresser K, O'Donnell P, Hutchinson L. The utility of MYC and FLT4 in the diagnosis and treatment of postradiation atypical vascular lesion and angiosarcoma of the breast. Hum Pathol. 2015 Jun; 46(6):868-75. PMID: 25864386.
      Citations: 17     Fields:    Translation:Humans
    46. Fang M, Ou J, Hutchinson L, Green MR. The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island Methylator phenotype. Mol Cell. 2014 Sep 18; 55(6):904-915. PMID: 25219500.
      Citations: 96     Fields:    Translation:HumansAnimalsCells
    47. Ma L, Shan Y, Bai R, Xue L, Eide CA, Ou J, Zhu LJ, Hutchinson L, Cerny J, Khoury HJ, Sheng Z, Druker BJ, Li S, Green MR. A therapeutically targetable mechanism of BCR-ABL-independent imatinib resistance in chronic myeloid leukemia. Sci Transl Med. 2014 Sep 03; 6(252):252ra121. PMID: 25186176.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    48. Rosenblum F, Hutchinson LM, Garver J, Woda B, Cosar E, Kurian EM. Cytology specimens offer an effective alternative to formalin-fixed tissue as demonstrated by novel automated detection for ALK break-apart FISH testing and immunohistochemistry in lung adenocarcinoma. Cancer Cytopathol. 2014 Nov; 122(11):810-21. PMID: 25099128.
      Citations: 10     Fields:    Translation:Humans
    49. Lee, P.J., Owens, C.L., Hutchinson, L., Fischer, A.H. Intranuclear cytoplasmic inclusions are a specific feature of intraductal papillary mucinous neoplasms that distinguish contaminating gastric epithelium. DOI: http://dx.doi.org/10.1016/j.jasc.2013.12.003. Journal of the American Society of Cytopathology. 2014; 3(2):108-113. View Publication.
    50. Serra RW, Fang M, Park SM, Hutchinson L, Green MR. A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype. Elife. 2014 Mar 12; 3:e02313. PMID: 24623306.
      Citations: 96     Fields:    Translation:HumansAnimalsCells
    51. Wu X, Tomaszewicz K, Hutchinson L, Cosar E, Deng A. . Next Generation Sequencing in Differential Diagnosis of Childhood Melanoma from Spitz Nevus: A case report. DOI: http://ijcp.elmerpress.com/index.php/ijcp/article/view/152/108. International Journal of Clinical Pediatrics. 2014; 3(1):22-28.. View Publication.
    52. Zhou AG, Hutchinson LM, Cosar EF. Urine Cytopathology and Ancillary Methods (Review). DOI: http://dx.doi.org/10.1016/j.path.2013.10.003. Surgical Pathology Clinics. 2014; 7(1):77-88. View Publication.
    53. Cornejo KM, Hutchinson L, Deng A, Tomaszewicz K, Welch M, Lyle S, Dresser K, Cosar EF. BRAF/KRAS gene sequencing of sebaceous neoplasms after mismatch repair protein analysis. Hum Pathol. 2014 Jun; 45(6):1213-20. PMID: 24767862.
      Citations: 3     Fields:    Translation:HumansCells
    54. Lee PJ, Owens CL, Hutchinson L, Fischer AH. Intranuclear cytoplasmic inclusions are a specific feature of intraductal papillary mucinous neoplasms that distinguish contaminating gastric epithelium. J Am Soc Cytopathol. 2014 Mar - Apr; 3(2):108-113. PMID: 31051700.
      Citations:    Fields:    
    55. Ramanathan M, Cerny J, Tomaszewicz K, Hutchinson L, Bednarik J, Woda BA, Nath R. . Isolated Extra Medullary Relapse after Allogeneic Stem Cell Transplant in FLT3 Mutated Acute Myeloid leukemia (AML) While on FLT3 Inhibitor Sorafenib. DOI: http://dx.doi.org/10.4172/2329-8790.1000116. J Hematol Thromb Dis. 2013; 1(4):116. View Publication.
    56. Zhou AG, Hutchinson LM, Cosar EF. Urine Cytopathology and Ancillary Methods. Surg Pathol Clin. 2014 Mar; 7(1):77-88. PMID: 26839270.
      Citations: 5     Fields:    
    57. Cornejo KM, Hutchinson L, Cosar EF, Smith T, Tomaszewicz K, Dresser K, Deng A. Is it a primary or metastatic melanocytic neoplasm of the central nervous system?: A molecular based approach. Pathol Int. 2013 Nov; 63(11):559-64. PMID: 24274719.
      Citations: 3     Fields:    Translation:HumansCells
    58. Wang SA, Hutchinson L, Tang G, Chen SS, Miron PM, Huh YO, Jones DM, Bueso-Ramos C, Verstovsek S, Medeiros LJ, Miranda RN. Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease: clinical significance and comparison of chomosomal abnormalities in SM and AHNMD components. Am J Hematol. 2013 Mar; 88(3):219-24. PMID: 23440662.
      Citations: 31     Fields:    Translation:HumansCells
    59. Menon MP, Hutchinson L, Garver J, Jaffe ES, Woda BA. Transformation of follicular lymphoma to Epstein-Barr virus-related Hodgkin-like lymphoma. J Clin Oncol. 2013 Feb 10; 31(5):e53-6. PMID: 23295788.
      Citations: 10     Fields:    Translation:HumansCells
    60. Cerny J, Yu H, Ramanathan M, Raffel GD, Walsh WV, Fortier N, Shanahan L, O'Rourke E, Bednarik J, Barton B, Kroll-Desrosiers A, Hao S, Woda B, Hutchinson L, Evens AM, Rosmarin AG, Nath R. Expression of CD25 independently predicts early treatment failure of acute myeloid leukaemia (AML). Br J Haematol. 2013 Jan; 160(2):262-6. PMID: 23116454.
      Citations: 20     Fields:    Translation:HumansCells
    61. Zhang H, Peng C, Hu Y, Li H, Sheng Z, Chen Y, Sullivan C, Cerny J, Hutchinson L, Higgins A, Miron P, Zhang X, Brehm MA, Li D, Green MR, Li S. The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells. Nat Genet. 2012 Jul 15; 44(8):861-71. PMID: 22797726.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    62. Piperdi B, Walsh WV, Bradley K, Zhou Z, Bathini V, Hanrahan-Boshes M, Hutchinson L, Perez-Soler R. Phase-I/II study of bortezomib in combination with carboplatin and bevacizumab as first-line therapy in patients with advanced non-small-cell lung cancer. J Thorac Oncol. 2012 Jun; 7(6):1032-40. PMID: 22534815.
      Citations: 20     Fields:    Translation:HumansCTClinical Trials
    63. Hure MC, Elco CP, Ward D, Hutchinson L, Meng X, Dorfman DM, Yu H. Histiocytic sarcoma arising from clonally related mantle cell lymphoma. J Clin Oncol. 2012 Feb 10; 30(5):e49-53. PMID: 22184374.
      Citations: 11     Fields:    Translation:HumansCells
    64. Kurian EM, Caporelli ML, Baker S, Woda B, Cosar EF, Hutchinson L. Cervista HR and HPV 16/18 assays vs hybrid capture 2 assay: outcome comparison in women with negative cervical cytology. Am J Clin Pathol. 2011 Nov; 136(5):808-16. PMID: 22031321.
      Citations: 9     Fields:    Translation:HumansCells
    65. Dvorak K, Goldman A, Kong J, Lynch JP, Hutchinson L, Houghton JM, Chen H, Chen X, Krishnadath KK, Westra WM. Molecular mechanisms of Barrett's esophagus and adenocarcinoma. Ann N Y Acad Sci. 2011 Sep; 1232:381-91. PMID: 21950830.
      Citations: 10     Fields:    Translation:Humans
    66. Shi M, Miron PM, Hutchinson L, Woda BA, Nath R, Cerny J, Yu H. Anaplastic lymphoma kinase-positive large B-cell lymphoma with complex karyotype and novel ALK gene rearrangements. Hum Pathol. 2011 Oct; 42(10):1562-7. PMID: 21497367.
      Citations: 6     Fields:    Translation:Humans
    67. Hutchinson L, Stenstrom B, Chen D, Piperdi B, Levey S, Lyle S, Wang TC, Houghton J. Human Barrett's adenocarcinoma of the esophagus, associated myofibroblasts, and endothelium can arise from bone marrow-derived cells after allogeneic stem cell transplant. Stem Cells Dev. 2011 Jan; 20(1):11-7. PMID: 20677919.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    68. Cerny J, Wang S, Miron P, Hutchinson L, Brettler D. EBV-negative Hodgkin lymphoma in ZAP-70-positive B-cell lymphocytic leukemia patient. Ann Hematol. 2009 May; 88(5):495-7. PMID: 18843488.
      Citations: 2     Fields:    Translation:Humans
    69. Cerny J, Fadare O, Hutchinson L, Wang SA. Clinicopathological features of extramedullary recurrence/relapse of multiple myeloma. Eur J Haematol. 2008 Jul; 81(1):65-9. PMID: 18462256.
      Citations: 10     Fields:    Translation:Humans
    70. Pozdnyakova O, Stachurski D, Hutchinson L, Ramakrishnan S, Miron PM. Trisomy 8 in B-cell chronic lymphocytic leukemia. Cancer Genet Cytogenet. 2008 May; 183(1):49-52. PMID: 18474297.
      Citations: 2     Fields:    Translation:HumansCells
    71. Banyard J, Hutchinson LM, Zetter BR. Thymosin beta-NB is the human isoform of rat thymosin beta15. Ann N Y Acad Sci. 2007 Sep; 1112:286-96. PMID: 17567946.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    72. Wang SA, Yue G, Hutchinson L, Landry ML, Hasserjian RP, Hao S, Galili N, Raza A, Woda BA. Myelodysplastic syndrome with pure red cell aplasia shows characteristic clinicopathological features and clonal T-cell expansion. Br J Haematol. 2007 Jul; 138(2):271-5. PMID: 17542981.
      Citations: 3     Fields:    Translation:HumansCells
    73. Stachurski D, Miron PM, Al-Homsi S, Hutchinson L, Harris NL, Woda B, Wang SA. Anaplastic lymphoma kinase-positive diffuse large B-cell lymphoma with a complex karyotype and cryptic 3' ALK gene insertion to chromosome 4 q22-24. Hum Pathol. 2007 Jun; 38(6):940-5. PMID: 17509395.
      Citations: 16     Fields:    Translation:HumansCells
    74. Banyard J, Bao L, Hofer MD, Zurakowski D, Spivey KA, Feldman AS, Hutchinson LM, Kuefer R, Rubin MA, Zetter BR. Collagen XXIII expression is associated with prostate cancer recurrence and distant metastases. Clin Cancer Res. 2007 May 01; 13(9):2634-42. PMID: 17473194.
      Citations: 23     Fields:    Translation:HumansCells
    75. Almog N, Henke V, Flores L, Hlatky L, Kung AL, Wright RD, Berger R, Hutchinson L, Naumov GN, Bender E, Akslen LA, Achilles EG, Folkman J. Prolonged dormancy of human liposarcoma is associated with impaired tumor angiogenesis. FASEB J. 2006 May; 20(7):947-9. PMID: 16638967.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    76. Hutchinson LM, Chang EL, Becker CM, Shih MC, Brice M, DeWolf WC, Gaston SM, Zetter BR. Use of thymosin beta15 as a urinary biomarker in human prostate cancer. Prostate. 2005 Jul 01; 64(2):116-27. PMID: 15666387.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    77. Hutchinson LM, Chang EL, Becker CM, Ushiyama N, Behonick D, Shih MC, DeWolf WC, Gaston SM, Zetter BR. Development of a sensitive and specific enzyme-linked immunosorbent assay for thymosin beta15, a urinary biomarker of human prostate cancer. Clin Biochem. 2005 Jun; 38(6):558-71. PMID: 15885237.
      Citations: 6     Fields:    Translation:HumansCells
    78. Lin J, Hutchinson L, Gaston SM, Raab G, Freeman MR. BAG-1 is a novel cytoplasmic binding partner of the membrane form of heparin-binding EGF-like growth factor: a unique role for proHB-EGF in cell survival regulation. J Biol Chem. 2001 Aug 10; 276(32):30127-32. PMID: 11340068.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    79. Eadie JS, Kim SW, Allen PG, Hutchinson LM, Kantor JD, Zetter BR. C-terminal variations in beta-thymosin family members specify functional differences in actin-binding properties. J Cell Biochem. 2000 Mar; 77(2):277-87. PMID: 10723093.
      Citations: 4     Fields:    Translation:AnimalsCells
    80. Hutchinson L, Johnson DC. Herpes simplex virus glycoprotein K promotes egress of virus particles. J Virol. 1995 Sep; 69(9):5401-13. PMID: 7636985.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    81. Hutchinson L, Roop-Beauchamp C, Johnson DC. Herpes simplex virus glycoprotein K is known to influence fusion of infected cells, yet is not on the cell surface. J Virol. 1995 Jul; 69(7):4556-63. PMID: 7769723.
      Citations: 45     Fields:    Translation:AnimalsCells
    82. Hutchinson L, Graham FL, Cai W, Debroy C, Person S, Johnson DC. Herpes simplex virus (HSV) glycoproteins B and K inhibit cell fusion induced by HSV syncytial mutants. Virology. 1993 Oct; 196(2):514-31. PMID: 8396800.
      Citations: 21     Fields:    Translation:AnimalsCells
    83. Roop C, Hutchinson L, Johnson DC. A mutant herpes simplex virus type 1 unable to express glycoprotein L cannot enter cells, and its particles lack glycoprotein H. J Virol. 1993 Apr; 67(4):2285-97. PMID: 8383241.
      Citations: 176     Fields:    Translation:HumansAnimalsCells
    84. Hutchinson L, Goldsmith K, Snoddy D, Ghosh H, Graham FL, Johnson DC. Identification and characterization of a novel herpes simplex virus glycoprotein, gK, involved in cell fusion. J Virol. 1992 Sep; 66(9):5603-9. PMID: 1323714.
      Citations: 80     Fields:    Translation:HumansCells
    85. Hutchinson L, Browne H, Wargent V, Davis-Poynter N, Primorac S, Goldsmith K, Minson AC, Johnson DC. A novel herpes simplex virus glycoprotein, gL, forms a complex with glycoprotein H (gH) and affects normal folding and surface expression of gH. J Virol. 1992 Apr; 66(4):2240-50. PMID: 1312629.
      Citations: 171     Fields:    Translation:HumansAnimalsCells
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