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Connection

David Harlan to Diabetes Mellitus, Type 1

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This is a "connection" page, showing publications David Harlan has written about Diabetes Mellitus, Type 1.
David Harlan
Connection Strength
6.634
Diabetes Mellitus, Type 1
  1. Russell MA, Redick SD, Blodgett DM, Richardson SJ, Leete P, Krogvold L, Dahl-J?rgensen K, Bottino R, Brissova M, Spaeth JM, Babon JAB, Haliyur R, Powers AC, Yang C, Kent SC, Derr AG, Kucukural A, Garber MG, Morgan NG, Harlan DM. HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet ?-Cells From Donors With Type 1 Diabetes. Diabetes. 2019 05; 68(5):988-1001.
    View in: PubMed
    Score: 0.440
  2. Rother KI, Harlan DM. Comment on: Keenan et al. (2010) residual insulin production and pancreatic ?-Cell turnover after 50 years of diabetes: Joslin Medalist Study. Diabetes 2010;59:2846-2853. Diabetes. 2010 Dec; 59(12):e26; author reply e27.
    View in: PubMed
    Score: 0.249
  3. Harlan DM, Lee MM. Infant formula, autoimmune triggers, and type 1 diabetes. N Engl J Med. 2010 Nov 11; 363(20):1961-3.
    View in: PubMed
    Score: 0.248
  4. Rother KI, Spain LM, Wesley RA, Digon BJ, Baron A, Chen K, Nelson P, Dosch HM, Palmer JP, Brooks-Worrell B, Ring M, Harlan DM. Effects of exenatide alone and in combination with daclizumab on beta-cell function in long-standing type 1 diabetes. Diabetes Care. 2009 Dec; 32(12):2251-7.
    View in: PubMed
    Score: 0.229
  5. Harlan DM, Kenyon NS, Korsgren O, Roep BO. Current advances and travails in islet transplantation. Diabetes. 2009 Oct; 58(10):2175-84.
    View in: PubMed
    Score: 0.229
  6. Khan MH, Harlan DM. Counterpoint: clinical islet transplantation: not ready for prime time. Diabetes Care. 2009 Aug; 32(8):1570-4.
    View in: PubMed
    Score: 0.227
  7. Liu EH, Digon BJ, Hirshberg B, Chang R, Wood BJ, Neeman Z, Kam A, Wesley RA, Polly SM, Hofmann RM, Rother KI, Harlan DM. Pancreatic beta cell function persists in many patients with chronic type 1 diabetes, but is not dramatically improved by prolonged immunosuppression and euglycaemia from a beta cell allograft. Diabetologia. 2009 Jul; 52(7):1369-80.
    View in: PubMed
    Score: 0.223
  8. Pechhold K, Koczwara K, Zhu X, Harrison VS, Walker G, Lee J, Harlan DM. Blood glucose levels regulate pancreatic beta-cell proliferation during experimentally-induced and spontaneous autoimmune diabetes in mice. PLoS One. 2009; 4(3):e4827.
    View in: PubMed
    Score: 0.221
  9. Pechhold K, Zhu X, Harrison VS, Lee J, Chakrabarty S, Koczwara K, Gavrilova O, Harlan DM. Dynamic changes in pancreatic endocrine cell abundance, distribution, and function in antigen-induced and spontaneous autoimmune diabetes. Diabetes. 2009 May; 58(5):1175-84.
    View in: PubMed
    Score: 0.220
  10. Pechhold K, Chakrabarty S, Harlan DM. Cytotoxic T cell-mediated diabetes in RIP-CD80 transgenic mice: autoantigen peptide sensitivity and fine specificity. Ann N Y Acad Sci. 2007 Apr; 1103:132-42.
    View in: PubMed
    Score: 0.192
  11. Harlan DM, von Herrath M. Immune intervention with anti-CD3 in diabetes. Nat Med. 2005 Jul; 11(7):716-8.
    View in: PubMed
    Score: 0.171
  12. Naftanel MA, Harlan DM. Pancreatic islet transplantation. PLoS Med. 2004 Dec; 1(3):e58; quiz e75.
    View in: PubMed
    Score: 0.164
  13. Rother KI, Harlan DM. Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus. J Clin Invest. 2004 Oct; 114(7):877-83.
    View in: PubMed
    Score: 0.162
  14. Harlan DM, Rother KI. Islet transplantation as a treatment for diabetes. N Engl J Med. 2004 May 13; 350(20):2104; author reply 2104.
    View in: PubMed
    Score: 0.158
  15. Shalev A, Patterson NB, Hirshberg B, Rother KI, Harlan DM. Resistin serum levels in type 1 diabetes pre- and post-islet transplantation. Metabolism. 2004 Apr; 53(4):403-4.
    View in: PubMed
    Score: 0.157
  16. Hirshberg B, Rother KI, Digon III BJ, Venstrom J, Harlan DM. State of the art: islet transplantation for the cure of type 1 diabetes mellitus. Rev Endocr Metab Disord. 2003 Dec; 4(4):381-9.
    View in: PubMed
    Score: 0.153
  17. Hirshberg B, Rother KI, Digon BJ, Lee J, Gaglia JL, Hines K, Read EJ, Chang R, Wood BJ, Harlan DM. Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience. Diabetes Care. 2003 Dec; 26(12):3288-95.
    View in: PubMed
    Score: 0.153
  18. Digon BJ, Rother KI, Hirshberg B, Harlan DM. Sirolimus-induced interstitial pneumonitis in an islet transplant recipient. Diabetes Care. 2003 Nov; 26(11):3191.
    View in: PubMed
    Score: 0.152
  19. Hirshberg B, Rother KI, Harlan DM. Islet transplantation: where do we stand now? Diabetes Metab Res Rev. 2003 May-Jun; 19(3):175-8; discussion 175.
    View in: PubMed
    Score: 0.147
  20. Derr AG, Arowosegbe A, Satish B, Redick SD, Qaisar N, Guo Z, Vanderleeden E, Trombly MI, Baer CE, Harlan DM, Greiner DL, Garber M, Wang JP. An Early Islet Transcriptional Signature Is Associated With Local Inflammation in Autoimmune Diabetes. Diabetes. 2023 Feb 01; 72(2):261-274.
    View in: PubMed
    Score: 0.144
  21. Hirshberg B, Montgomery S, Wysoki MG, Xu H, Tadaki D, Lee J, Hines K, Gaglia J, Patterson N, Leconte J, Hale D, Chang R, Kirk AD, Harlan DM. Pancreatic islet transplantation using the nonhuman primate (rhesus) model predicts that the portal vein is superior to the celiac artery as the islet infusion site. Diabetes. 2002 Jul; 51(7):2135-40.
    View in: PubMed
    Score: 0.139
  22. Leite NC, Sintov E, Meissner TB, Brehm MA, Greiner DL, Harlan DM, Melton DA. Modeling Type 1 Diabetes In?Vitro Using Human Pluripotent Stem Cells. Cell Rep. 2020 07 14; 32(2):107894.
    View in: PubMed
    Score: 0.121
  23. Wright JJ, Saunders DC, Dai C, Poffenberger G, Cairns B, Serreze DV, Harlan DM, Bottino R, Brissova M, Powers AC. Decreased pancreatic acinar cell number in type 1 diabetes. Diabetologia. 2020 07; 63(7):1418-1423.
    View in: PubMed
    Score: 0.120
  24. Haliyur R, Tong X, Sanyoura M, Shrestha S, Lindner J, Saunders DC, Aramandla R, Poffenberger G, Redick SD, Bottino R, Prasad N, Levy SE, Blind RD, Harlan DM, Philipson LH, Stein RW, Brissova M, Powers AC. Human islets expressing HNF1A variant have defective ? cell transcriptional regulatory networks. J Clin Invest. 2019 01 02; 129(1):246-251.
    View in: PubMed
    Score: 0.108
  25. Sobel DO, Goyal D, Ahvazi B, Yoon JW, Chung YH, Bagg A, Harlan DM. Low dose poly I:C prevents diabetes in the diabetes prone BB rat. J Autoimmun. 1998 Aug; 11(4):343-52.
    View in: PubMed
    Score: 0.106
  26. Marre ML, McGinty JW, Chow IT, DeNicola ME, Beck NW, Kent SC, Powers AC, Bottino R, Harlan DM, Greenbaum CJ, Kwok WW, Piganelli JD, James EA. Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes. Diabetes. 2018 07; 67(7):1356-1368.
    View in: PubMed
    Score: 0.104
  27. Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, Sanyoura M, Philipson LH, Atkinson M, Harlan DM, Levy SE, Prasad N, Stein R, Powers AC. a Cell Function and Gene Expression Are Compromised in Type 1 Diabetes. Cell Rep. 2018 03 06; 22(10):2667-2676.
    View in: PubMed
    Score: 0.103
  28. Harlan DM. Response to Comment on Harlan. Islet Transplantation for Hypoglycemia Unawareness/Severe Hypoglycemia: Caveat Emptor. Diabetes Care 2016;39:1072-1074. Diabetes Care. 2017 08; 40(8):e113-e114.
    View in: PubMed
    Score: 0.099
  29. Roberts FR, Hupple C, Norowski E, Walsh NC, Przewozniak N, Aryee KE, Van Dessel FM, Jurczyk A, Harlan DM, Greiner DL, Bortell R, Yang C. Possible type 1 diabetes risk prediction: Using ultrasound imaging to assess pancreas inflammation in the inducible autoimmune diabetes BBDR model. PLoS One. 2017; 12(6):e0178641.
    View in: PubMed
    Score: 0.098
  30. El-Khatib FH, Balliro C, Hillard MA, Magyar KL, Ekhlaspour L, Sinha M, Mondesir D, Esmaeili A, Hartigan C, Thompson MJ, Malkani S, Lock JP, Harlan DM, Clinton P, Frank E, Wilson DM, DeSalvo D, Norlander L, Ly T, Buckingham BA, Diner J, Dezube M, Young LA, Goley A, Kirkman MS, Buse JB, Zheng H, Selagamsetty RR, Damiano ER, Russell SJ. Home use of a bihormonal bionic pancreas versus insulin pump therapy in adults with type 1 diabetes: a multicentre randomised crossover trial. Lancet. 2017 01 28; 389(10067):369-380.
    View in: PubMed
    Score: 0.095
  31. Babon JA, DeNicola ME, Blodgett DM, Cr?vecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC. Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nat Med. 2016 12; 22(12):1482-1487.
    View in: PubMed
    Score: 0.094
  32. Harlan DM. Islet Transplantation for Hypoglycemia Unawareness/Severe Hypoglycemia: Caveat Emptor. Diabetes Care. 2016 07; 39(7):1072-4.
    View in: PubMed
    Score: 0.091
  33. Imagawa A, Hanafusa T, Itoh N, Miyagawa J, Nakajima H, Namba M, Kuwajima M, Tamura S, Kawata S, Matsuzawa Y, Harlan DM. Islet-infiltrating t lymphocytes in insulin-dependent diabetic patients express CD80 (B7-1) and CD86 (B7-2). J Autoimmun. 1996 Jun; 9(3):391-6.
    View in: PubMed
    Score: 0.091
  34. Delong T, Wiles TA, Baker RL, Bradley B, Barbour G, Reisdorph R, Armstrong M, Powell RL, Reisdorph N, Kumar N, Elso CM, DeNicola M, Bottino R, Powers AC, Harlan DM, Kent SC, Mannering SI, Haskins K. Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion. Science. 2016 Feb 12; 351(6274):711-4.
    View in: PubMed
    Score: 0.089
  35. Blau JE, Abegg MR, Flegel WA, Zhao X, Harlan DM, Rother KI. Long-term immunosuppression after solitary islet transplantation is associated with preserved C-peptide secretion for more than a decade. Am J Transplant. 2015 Nov; 15(11):2995-3001.
    View in: PubMed
    Score: 0.086
  36. Sarkar G, Alattar M, Brown RJ, Quon MJ, Harlan DM, Rother KI. Response to comment on Sarkar et al. Exenatide treatment for 6 months improves insulin sensitivity in adults with type 1 diabetes. Diabetes care 2014;37:666-670. Diabetes Care. 2014 Oct; 37(10):e219-20.
    View in: PubMed
    Score: 0.081
  37. Fuchs YF, Adler K, Lindner A, Karasinsky A, Wilhelm C, Weigelt M, Balke H, F?rtsch K, Mortler-Hildebrandt LF, Harlan DM, Pechhold K, Ziegler AG, Bonifacio E. IGRP and insulin vaccination induce CD8+ T cell-mediated autoimmune diabetes in the RIP-CD80GP mouse. Clin Exp Immunol. 2014 May; 176(2):199-206.
    View in: PubMed
    Score: 0.079
  38. Miao F, Chen Z, Genuth S, Paterson A, Zhang L, Wu X, Li SM, Cleary P, Riggs A, Harlan DM, Lorenzi G, Kolterman O, Sun W, Lachin JM, Natarajan R. Evaluating the role of epigenetic histone modifications in the metabolic memory of type 1 diabetes. Diabetes. 2014 May; 63(5):1748-62.
    View in: PubMed
    Score: 0.077
  39. Sarkar G, Alattar M, Brown RJ, Quon MJ, Harlan DM, Rother KI. Exenatide treatment for 6 months improves insulin sensitivity in adults with type 1 diabetes. Diabetes Care. 2014; 37(3):666-70.
    View in: PubMed
    Score: 0.076
  40. Simmons JH, Chen V, Miller KM, McGill JB, Bergenstal RM, Goland RS, Harlan DM, Largay JF, Massaro EM, Beck RW. Differences in the management of type 1 diabetes among adults under excellent control compared with those under poor control in the T1D Exchange Clinic Registry. Diabetes Care. 2013 Nov; 36(11):3573-7.
    View in: PubMed
    Score: 0.075
  41. Burbelo PD, Lebovitz EE, Bren KE, Bayat A, Paviol S, Wenzlau JM, Barriga KJ, Rewers M, Harlan DM, Iadarola MJ. Extrapancreatic autoantibody profiles in type I diabetes. PLoS One. 2012; 7(9):e45216.
    View in: PubMed
    Score: 0.070
  42. Greiner DL, Brehm MA, Hosur V, Harlan DM, Powers AC, Shultz LD. Humanized mice for the study of type 1 and type 2 diabetes. Ann N Y Acad Sci. 2011 Dec; 1245:55-8.
    View in: PubMed
    Score: 0.067
  43. Brown RJ, Wijewickrama RC, Harlan DM, Rother KI. Uncoupling intensive insulin therapy from weight gain and hypoglycemia in type 1 diabetes. Diabetes Technol Ther. 2011 Apr; 13(4):457-60.
    View in: PubMed
    Score: 0.063
  44. Rother KI, Brown RJ, Morales MM, Wright E, Duan Z, Campbell C, Hardin DS, Popovic J, McEvoy RC, Harlan DM, Orlander PR, Brod SA. Effect of ingested interferon-alpha on beta-cell function in children with new-onset type 1 diabetes. Diabetes Care. 2009 Jul; 32(7):1250-5.
    View in: PubMed
    Score: 0.056
  45. Craig AT, Gavrilova O, Dwyer NK, Jou W, Pack S, Liu E, Pechhold K, Schmidt M, McAlister VJ, Chiorini JA, Blanchette-Mackie EJ, Harlan DM, Owens RA. Transduction of rat pancreatic islets with pseudotyped adeno-associated virus vectors. Virol J. 2009 May 18; 6:61.
    View in: PubMed
    Score: 0.056
  46. Ren J, Jin P, Wang E, Liu E, Harlan DM, Li X, Stroncek DF. Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation. J Transl Med. 2007 Jan 03; 5:1.
    View in: PubMed
    Score: 0.047
  47. Dy EC, Harlan DM, Rother KI. Assessment of islet function following islet and pancreas transplantation. Curr Diab Rep. 2006 Aug; 6(4):316-22.
    View in: PubMed
    Score: 0.046
  48. Kang EM, Zickler PP, Burns S, Langemeijer SM, Brenner S, Phang OA, Patterson N, Harlan D, Tisdale JF. Hematopoietic stem cell transplantation prevents diabetes in NOD mice but does not contribute to significant islet cell regeneration once disease is established. Exp Hematol. 2005 Jun; 33(6):699-705.
    View in: PubMed
    Score: 0.042
  49. Herold KC, Gitelman SE, Masharani U, Hagopian W, Bisikirska B, Donaldson D, Rother K, Diamond B, Harlan DM, Bluestone JA. A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes. 2005 Jun; 54(6):1763-9.
    View in: PubMed
    Score: 0.042
  50. Sundstrom J, Vanderleeden E, Barton NJ, Redick SD, Dawes P, Murray LF, Olson MN, Tran K, Chigas SM, Orszulak AR, Church GM, Readhead B, Oh HS, Harlan DM, Knipe DM, Wang JP, Chan Y, Lim ET. Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer's Disease and Autoimmune Diseases. Cells. 2024 11 29; 13(23).
    View in: PubMed
    Score: 0.041
  51. Steele C, Hagopian WA, Gitelman S, Masharani U, Cavaghan M, Rother KI, Donaldson D, Harlan DM, Bluestone J, Herold KC. Insulin secretion in type 1 diabetes. Diabetes. 2004 Feb; 53(2):426-33.
    View in: PubMed
    Score: 0.039
  52. Harlan DM. Islet cell allotransplantation as a model system for a bioengineering approach to reparative medicine: immunological concerns. Ann N Y Acad Sci. 2002 Jun; 961:331-4.
    View in: PubMed
    Score: 0.034
  53. Herold KC, Hagopian W, Auger JA, Poumian-Ruiz E, Taylor L, Donaldson D, Gitelman SE, Harlan DM, Xu D, Zivin RA, Bluestone JA. Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N Engl J Med. 2002 May 30; 346(22):1692-8.
    View in: PubMed
    Score: 0.034
  54. Herrera PL, Harlan DM, Fossati L, Izui S, Huarte J, Orci L, Vassalli JD, Vassalli P. A CD8+ T-lymphocyte-mediated and CD4+ T-lymphocyte-independent autoimmune diabetes of early onset in transgenic mice. Diabetologia. 1994 Dec; 37(12):1277-9.
    View in: PubMed
    Score: 0.020
  55. Kenyon NS, Chatzipetrou M, Masetti M, Ranuncoli A, Oliveira M, Wagner JL, Kirk AD, Harlan DM, Burkly LC, Ricordi C. Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154. Proc Natl Acad Sci U S A. 1999 Jul 06; 96(14):8132-7.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.