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Connection

Susan Swain to Interleukin-4

This is a "connection" page, showing publications Susan Swain has written about Interleukin-4.
Connection Strength

1.850
  1. Brown DM, Kamperschroer C, Dilzer AM, Roberts DM, Swain SL. IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells. Cell Immunol. 2009; 257(1-2):69-79.
    View in: PubMed
    Score: 0.319
  2. Bradley LM, Yoshimoto K, Swain SL. The cytokines IL-4, IFN-gamma, and IL-12 regulate the development of subsets of memory effector helper T cells in vitro. J Immunol. 1995 Aug 15; 155(4):1713-24.
    View in: PubMed
    Score: 0.124
  3. Croft M, Swain SL. Recently activated naive CD4 T cells can help resting B cells, and can produce sufficient autocrine IL-4 to drive differentiation to secretion of T helper 2-type cytokines. J Immunol. 1995 May 01; 154(9):4269-82.
    View in: PubMed
    Score: 0.122
  4. Swain SL. IL4 dictates T-cell differentiation. Res Immunol. 1993 Oct; 144(8):616-20.
    View in: PubMed
    Score: 0.109
  5. Bradley LM, Duncan DD, Yoshimoto K, Swain SL. Memory effectors: a potent, IL-4-secreting helper T cell population that develops in vivo after restimulation with antigen. J Immunol. 1993 Apr 15; 150(8 Pt 1):3119-30.
    View in: PubMed
    Score: 0.106
  6. Swain SL, Huston G, Tonkonogy S, Weinberg A. Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype. J Immunol. 1991 Nov 01; 147(9):2991-3000.
    View in: PubMed
    Score: 0.096
  7. Bradley LM, Duncan DD, Tonkonogy S, Swain SL. Characterization of antigen-specific CD4+ effector T cells in vivo: immunization results in a transient population of MEL-14-, CD45RB- helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma. J Exp Med. 1991 Sep 01; 174(3):547-59.
    View in: PubMed
    Score: 0.094
  8. Croft M, Swain SL. B cell response to fresh and effector T helper cells. Role of cognate T-B interaction and the cytokines IL-2, IL-4, and IL-6. J Immunol. 1991 Jun 15; 146(12):4055-64.
    View in: PubMed
    Score: 0.093
  9. Kubota E, McKenzie DT, Dutton RW, Swain SL. Role of T cells in the B-cell response: glutaraldehyde-fixed T-helper hybridoma cells synergize with the lymphokine IL-4 to induce B-cell activation and proliferation. Immunology. 1991 Jan; 72(1):40-7.
    View in: PubMed
    Score: 0.090
  10. Swain SL, Weinberg AD, English M, Huston G. IL-4 directs the development of Th2-like helper effectors. J Immunol. 1990 Dec 01; 145(11):3796-806.
    View in: PubMed
    Score: 0.090
  11. Haynes L, Eaton SM, Burns EM, Randall TD, Swain SL. CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15053-8.
    View in: PubMed
    Score: 0.055
  12. Lee BO, Haynes L, Eaton SM, Swain SL, Randall TD. The biological outcome of CD40 signaling is dependent on the duration of CD40 ligand expression: reciprocal regulation by interleukin (IL)-4 and IL-12. J Exp Med. 2002 Sep 02; 196(5):693-704.
    View in: PubMed
    Score: 0.051
  13. Haynes L, Linton PJ, Eaton SM, Tonkonogy SL, Swain SL. Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice. J Exp Med. 1999 Oct 04; 190(7):1013-24.
    View in: PubMed
    Score: 0.041
  14. Dubey C, Croft M, Swain SL. Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals. J Immunol. 1996 Oct 15; 157(8):3280-9.
    View in: PubMed
    Score: 0.034
  15. Yoshimoto K, Swain SL, Bradley LM. Enhanced development of Th2-like primary CD4 effectors in response to sustained exposure to limited rIL-4 in vivo. J Immunol. 1996 May 01; 156(9):3267-74.
    View in: PubMed
    Score: 0.033
  16. Brodeur TY, Robidoux TE, Weinstein JS, Craft J, Swain SL, Marshak-Rothstein A. IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells. J Immunol. 2015 Dec 01; 195(11):5251-60.
    View in: PubMed
    Score: 0.032
  17. Tsukamoto H, Senju S, Matsumura K, Swain SL, Nishimura Y. IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age. Nat Commun. 2015 Apr 07; 6:6702.
    View in: PubMed
    Score: 0.030
  18. Bradley LM, Watson SR, Swain SL. Entry of naive CD4 T cells into peripheral lymph nodes requires L-selectin. J Exp Med. 1994 Dec 01; 180(6):2401-6.
    View in: PubMed
    Score: 0.030
  19. Croft M, Carter L, Swain SL, Dutton RW. Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles. J Exp Med. 1994 Nov 01; 180(5):1715-28.
    View in: PubMed
    Score: 0.029
  20. Tonkonogy SL, Swain SL. Distinct lymphokine production by CD4+ T cells isolated from mucosal and systemic lymphoid organs. Immunology. 1993 Dec; 80(4):574-80.
    View in: PubMed
    Score: 0.028
  21. Croft M, Swain SL. Analysis of CD4+ T cells that provide contact-dependent bystander help to B cells. J Immunol. 1992 Nov 15; 149(10):3157-65.
    View in: PubMed
    Score: 0.026
  22. Bradley LM, Atkins GG, Swain SL. Long-term CD4+ memory T cells from the spleen lack MEL-14, the lymph node homing receptor. J Immunol. 1992 Jan 15; 148(2):324-31.
    View in: PubMed
    Score: 0.024
  23. Croft M, Swain SL. B cell response to T helper cell subsets. II. Both the stage of T cell differentiation and the cytokines secreted determine the extent and nature of helper activity. J Immunol. 1991 Dec 01; 147(11):3679-89.
    View in: PubMed
    Score: 0.024
  24. Swain SL. Lymphokines and the immune response: the central role of interleukin-2. Curr Opin Immunol. 1991 Jun; 3(3):304-10.
    View in: PubMed
    Score: 0.023
  25. Tonkonogy SL, McKenzie DT, Swain SL. Regulation of isotype production by IL-4 and IL-5. Effects of lymphokines on Ig production depend on the state of activation of the responding B cells. J Immunol. 1989 Jun 15; 142(12):4351-60.
    View in: PubMed
    Score: 0.020
  26. Swain SL, McKenzie DT, Dutton RW, Tonkonogy SL, English M. The role of IL4 and IL5: characterization of a distinct helper T cell subset that makes IL4 and IL5 (Th2) and requires priming before induction of lymphokine secretion. Immunol Rev. 1988 Feb; 102:77-105.
    View in: PubMed
    Score: 0.018
  27. Swain SL, Dutton RW. B cell growth factor interactions. Adv Exp Med Biol. 1987; 213:215-25.
    View in: PubMed
    Score: 0.017
  28. Swain SL. Role of BCGFII in the differentiation to antibody secretion normal and tumor B cells. J Immunol. 1985 Jun; 134(6):3934-43.
    View in: PubMed
    Score: 0.015
  29. Swain SL, Dutton RW. T-cell factors that promote B-cell proliferation and differentiation. Contemp Top Mol Immunol. 1985; 10:219-29.
    View in: PubMed
    Score: 0.015
  30. Dutton RW, Wetzel GD, Swain SL. Partial purification and characterization of a BCGFII from EL4 culture supernatants. J Immunol. 1984 May; 132(5):2451-6.
    View in: PubMed
    Score: 0.014
  31. Kagnoff MF, Arner LS, Swain SL. Lymphokine-mediated activation of a T cell-dependent IgA antipolysaccharide response. J Immunol. 1983 Nov; 131(5):2210-4.
    View in: PubMed
    Score: 0.014
  32. Swain SL, Howard M, Kappler J, Marrack P, Watson J, Booth R, Wetzel GD, Dutton RW. Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med. 1983 Sep 01; 158(3):822-35.
    View in: PubMed
    Score: 0.014
  33. Pfeifer JD, McKenzie DT, Swain SL, Dutton RW. B cell stimulatory factor 1 (interleukin 4) is sufficient for the proliferation and differentiation of lectin-stimulated cytolytic T lymphocyte precursors. J Exp Med. 1987 Nov 01; 166(5):1464-70.
    View in: PubMed
    Score: 0.005
  34. Murray PD, McKenzie DT, Swain SL, Kagnoff MF. Interleukin 5 and interleukin 4 produced by Peyer's patch T cells selectively enhance immunoglobulin A expression. J Immunol. 1987 Oct 15; 139(8):2669-74.
    View in: PubMed
    Score: 0.005
  35. Southern SO, Swain SL, Dutton RW. B cell surface glycoprotein induced during growth response: molecular structure and expression pattern. J Immunol. 1987 Apr 15; 138(8):2568-75.
    View in: PubMed
    Score: 0.004
  36. Murray PD, Swain SL, Kagnoff MP. Regulation of the IgM and IgA anti-dextran B1355S response: synergy between IFN-gamma, BCGF II, and IL 2. J Immunol. 1985 Dec; 135(6):4015-20.
    View in: PubMed
    Score: 0.004
  37. Wetzel GD, Swain SL, Dutton RW, Kettman JR. Evidence for two distinct activation states available to B lymphocytes. J Immunol. 1984 Nov; 133(5):2327-32.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.