Loading...
Header Logo
Keywords
Last Name
Institution

Feng He PhD

TitleAssociate Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentMicrobiology and Physiological Systems
AddressUniversity of Massachusetts Medical School
55 Lake Avenue North
Worcester MA 01655
Phone508-856-3361
vCardDownload vCard
    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentMicrobiology and Physiological Systems


    Collapse Biography 
    Collapse education and training
    Beijing University of Agriculture, Haidian, , ChinaBSAnimal Science
    National Institute of Agronomy, Paris, , FranceMSGenetic & Molecular Biology
    National Institute of Agronomy, Paris, , FrancePHDGenetic & Molecular Biology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. He F, Celik A, Wu C, Jacobson A. General decapping activators target different subsets of inefficiently translated mRNAs. Elife. 2018 Dec 06; 7. PMID: 30520724.
      View in: PubMed
    2. Celik A, He F, Jacobson A. NMD monitors translational fidelity 24/7. Curr Genet. 2017 Dec; 63(6):1007-1010. PMID: 28536849.
      View in: PubMed
    3. Celik A, Baker R, He F, Jacobson A. High Resolution Profiling of NMD Targets in Yeast Reveals Translational Fidelity as a Basis for Substrate Selection. RNA. 2017 Feb 16. PMID: 28209632.
      View in: PubMed
    4. He F, Jacobson A. Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story. Annu Rev Genet. 2015; 49:339-66. PMID: 26436458.
      View in: PubMed
    5. He F, Jacobson A. Control of mRNA decapping by positive and negative regulatory elements in the Dcp2 C-terminal domain. RNA. 2015 Sep; 21(9):1633-47. PMID: 26184073.
      View in: PubMed
    6. Amcheslavsky A, Nie Y, Li Q, He F, Tsuda L, Markstein M, Ip YT. Gene expression profiling identifies the zinc-finger protein Charlatan as a regulator of intestinal stem cells in Drosophila. Development. 2014 Jul; 141(13):2621-32. PMID: 24961799.
      View in: PubMed
    7. He F, Li C, Roy B, Jacobson A. Yeast Edc3 targets RPS28B mRNA for decapping by binding to a 3' untranslated region decay-inducing regulatory element. Mol Cell Biol. 2014 Apr; 34(8):1438-51. PMID: 24492965.
      View in: PubMed
    8. He F, Ganesan R, Jacobson A. Intra- and intermolecular regulatory interactions in Upf1, the RNA helicase central to nonsense-mediated mRNA decay in yeast. Mol Cell Biol. 2013 Dec; 33(23):4672-84. PMID: 24100012.
      View in: PubMed
    9. Min EE, Roy B, Amrani N, He F, Jacobson A. Yeast Upf1 CH domain interacts with Rps26 of the 40S ribosomal subunit. RNA. 2013 Aug; 19(8):1105-15. PMID: 23801788.
      View in: PubMed
    10. Dong S, Jacobson A, He F. Degradation of YRA1 Pre-mRNA in the cytoplasm requires translational repression, multiple modular intronic elements, Edc3p, and Mex67p. PLoS Biol. 2010 Apr 27; 8(4):e1000360. PMID: 20463951.
      View in: PubMed
    11. He F, Amrani N, Johansson MJ, Jacobson A. Chapter 6. Qualitative and quantitative assessment of the activity of the yeast nonsense-mediated mRNA decay pathway. Methods Enzymol. 2008; 449:127-47. PMID: 19215756.
      View in: PubMed
    12. Johansson MJ, He F, Spatrick P, Li C, Jacobson A. Association of yeast Upf1p with direct substrates of the NMD pathway. Proc Natl Acad Sci U S A. 2007 Dec 26; 104(52):20872-7. PMID: 18087042.
      View in: PubMed
    13. Dong S, Li C, Zenklusen D, Singer RH, Jacobson A, He F. YRA1 autoregulation requires nuclear export and cytoplasmic Edc3p-mediated degradation of its pre-mRNA. Mol Cell. 2007 Feb 23; 25(4):559-73. PMID: 17317628.
      View in: PubMed
    14. Wang S, Farfan-Arribas DJ, Shen S, Chou TH, Hirsch A, He F, Lu S. Relative contributions of codon usage, promoter efficiency and leader sequence to the antigen expression and immunogenicity of HIV-1 Env DNA vaccine. Vaccine. 2006 May 22; 24(21):4531-40. PMID: 16140431.
      View in: PubMed
    15. He F, Li X, Spatrick P, Casillo R, Dong S, Jacobson A. Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5' to 3' mRNA decay pathways in yeast. Mol Cell. 2003 Dec; 12(6):1439-52. PMID: 14690598.
      View in: PubMed
    16. Li L, He F, Litofsky NS, Recht LD, Ross AH. Profiling of genes expressed by PTEN haploinsufficient neural precursor cells. Mol Cell Neurosci. 2003 Dec; 24(4):1051-61. PMID: 14697668.
      View in: PubMed
    17. Maderazo AB, Belk JP, He F, Jacobson A. Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are destabilized rapidly upon its restitution. Mol Cell Biol. 2003 Feb; 23(3):842-51. PMID: 12529390.
      View in: PubMed
    18. Liu H, Radhakrishnan P, Magoun L, Prabu M, Campellone KG, Savage P, He F, Schiffer CA, Leong JM. Point mutants of EHEC intimin that diminish Tir recognition and actin pedestal formation highlight a putative Tir binding pocket. Mol Microbiol. 2002 Sep; 45(6):1557-73. PMID: 12354225.
      View in: PubMed
    For assistance with using Profiles, please refer to the online tutorials or contact UMMS Help Desk or call 508-856-8643.
    He's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _