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Mark Steven Joel Klempner MD

TitleProfessor
InstitutionUniversity of Massachusetts Medical School
DepartmentMedicine
AddressMassBiologics
460 Walk Hilll Street
Boston MA 02126
Phone617-474-3250
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentMedicine
    DivisionMassachusetts Biological Laboratory


    Collapse Biography 
    Collapse education and training
    Weill Cornell Graduate School of Medical Sciences, New York, NY, United StatesMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hu Y, Kumru OS, Xiong J, Antunez LR, Hickey J, Wang Y, Cavacini L, Klempner M, Joshi SB, Volkin DB. Preformulation Characterization and Stability Assessments of Secretory IgA Monoclonal Antibodies as Potential Candidates for Passive Immunization by Oral Administration. J Pharm Sci. 2019 Jul 29. PMID: 31369743.
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    2. Wang Y, Esquivel R, Flingai S, Schiller ZA, Kern A, Agarwal S, Chu J, Patel A, Sullivan K, Wise MC, Broderick KE, Hu L, Weiner DB, Klempner MS. Anti-OspA DNA-Encoded Monoclonal Antibody Prevents Transmission of Spirochetes in Tick Challenge Providing Sterilizing Immunity in Mice. J Infect Dis. 2018 Nov 21. PMID: 30476132.
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    3. Giuntini S, Stoppato M, Sedic M, Ejemel M, Pondish JR, Wisheart D, Schiller ZA, Thomas WD, Barry EM, Cavacini LA, Klempner MS, Wang Y. Correction for Giuntini et al., "Identification and Characterization of Human Monoclonal Antibodies for Immunoprophylaxis against Enterotoxigenic Escherichia coli Infection". Infect Immun. 2018 Dec; 86(12). PMID: 30459206.
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    4. Giuntini S, Stoppato M, Sedic M, Ejemel M, Pondish JR, Wisheart D, Schiller ZA, Thomas WD, Barry EM, Cavacini LA, Klempner MS, Wang Y. Identification and Characterization of Human Monoclonal Antibodies for Immunoprophylaxis Against Enterotoxigenic Escherichia coli Infection. Infect Immun. 2018 Jun 04. PMID: 29866909.
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    5. Shandilya S, Kurt Yilmaz N, Sadowski A, Monir E, Schiller ZA, Thomas WD, Klempner MS, Schiffer CA, Wang Y. Structural and molecular analysis of a protective epitope of Lyme disease antigen OspA and antibody interactions. J Mol Recognit. 2016 Nov 16. PMID: 27859766.
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    6. Wang Y, Kern A, Boatright NK, Schiller ZA, Sadowski A, Ejemel M, Souders CA, Reimann KA, Hu L, Thomas WD, Klempner MS. Pre-exposure Prophylaxis With OspA-Specific Human Monoclonal Antibodies Protects Mice Against Tick Transmission of Lyme Disease Spirochetes. J Infect Dis. 2016 Jul 15; 214(2):205-11. PMID: 27338767.
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    7. Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, Souders CA, Piper AE, Goff A, Shamblin JD, Wollen SE, Sprague TR, Fusco ML, Pommert KB, Cavacini LA, Smith HL, Klempner M, Reimann KA, Krauland E, Gerngross TU, Wittrup KD, Saphire EO, Burton DR, Glass PJ, Ward AB, Walker LM. Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak. Science. 2016 Mar 4; 351(6277):1078-83. PMID: 26912366.
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    8. Tang KS, Klempner MS, Wormser GP, Marques AR, Alaedini A. Association of immune response to endothelial cell growth factor with early disseminated and late manifestations of Lyme disease but not posttreatment Lyme disease syndrome. Clin Infect Dis. 2015 Dec 1; 61(11):1703-6. PMID: 26219695.
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    9. Souders CA, Nelson SC, Wang Y, Crowley AR, Klempner MS, Thomas W. A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life. MAbs. 2015; 7(5):912-21. PMID: 26018774.
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    10. Vega NM, Allison KR, Samuels AN, Klempner MS, Collins JJ. Reply to Blair et al.: Dose-dependent effects and oxidative stress responses in antibiotic tolerance in Salmonella typhimurium. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):E4570. PMID: 24422210.
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    11. Klempner MS, Baker PJ, Shapiro ED, Marques A, Dattwyler RJ, Halperin JJ, Wormser GP. The reply. Am J Med. 2014 Feb; 127(2):e11-2. PMID: 24462014.
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    12. Vega NM, Allison KR, Samuels AN, Klempner MS, Collins JJ. Salmonella typhimurium intercepts Escherichia coli signaling to enhance antibiotic tolerance. Proc Natl Acad Sci U S A. 2013 Aug 27; 110(35):14420-5. PMID: 23946425.
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    13. Klempner MS, Baker PJ, Shapiro ED, Marques A, Dattwyler RJ, Halperin JJ, Wormser GP. Treatment trials for post-Lyme disease symptoms revisited. Am J Med. 2013 Aug; 126(8):665-9. PMID: 23764268.
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    14. Klempner MS, Halperin JJ, Baker PJ, Shapiro ED, O'Connell S, Fingerle V, Wormser GP. Lyme borreliosis: the challenge of accuracy. Neth J Med. 2012 Jan; 70(1):3-5. PMID: 22271807.
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    15. Klempner MS, Talbot EA, Lee SI, Zaki S, Ferraro MJ. Case records of the Massachusetts General Hospital. Case 25-2010. A 24-year-old woman with abdominal pain and shock. N Engl J Med. 2010 Aug 19; 363(8):766-77. PMID: 20818879.
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    16. Chandra A, Wormser GP, Klempner MS, Trevino RP, Crow MK, Latov N, Alaedini A. Anti-neural antibody reactivity in patients with a history of Lyme borreliosis and persistent symptoms. Brain Behav Immun. 2010 Aug; 24(6):1018-24. PMID: 20227484.
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    17. Feder HM, Johnson BJ, O'Connell S, Shapiro ED, Steere AC, Wormser GP. A critical appraisal of "chronic Lyme disease". N Engl J Med. 2007 Oct 4; 357(14):1422-30. PMID: 17914043.
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    18. Klempner MS, Unnasch TR, Hu LT. Taking a bite out of vector-transmitted infectious diseases. N Engl J Med. 2007 Jun 21; 356(25):2567-9. PMID: 17582066.
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    19. Zhao Z, McCloud B, Fleming R, Klempner MS. Borrelia burgdorferi-induced monocyte chemoattractant protein-1 production in vivo and in vitro. Biochem Biophys Res Commun. 2007 Jun 29; 358(2):528-33. PMID: 17485071.
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    20. Zhao Z, Fleming R, McCloud B, Klempner MS. CD14 mediates cross talk between mononuclear cells and fibroblasts for upregulation of matrix metalloproteinase 9 by Borrelia burgdorferi. Infect Immun. 2007 Jun; 75(6):3062-9. PMID: 17403874.
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    21. Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS, Krause PJ, Bakken JS, Strle F, Stanek G, Bockenstedt L, Fish D, Dumler JS, Nadelman RB. The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2006 Nov 1; 43(9):1089-134. PMID: 17029130.
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    22. Klempner M. Interview with Mark Klempner, MD, principal investigator, National Emerging Infectious Diseases Laboratories, and associate provost for research, Boston University School of Medicine. Biosecur Bioterror. 2006; 4(2):107-12. PMID: 16792478.
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    23. Wormser GP, Kaslow R, Tang J, Wade K, Liveris D, Schwartz I, Klempner M. Association between human leukocyte antigen class II alleles and genotype of Borrelia burgdorferi in patients with early lyme disease. J Infect Dis. 2005 Dec 01; 192(11):2020-6. PMID: 16267776.
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    24. Klempner MS, Wormser GH, Wade K, Trevino RP, Tang J, Kaslow RA, Schmid C. A case-control study to examine HLA haplotype associations in patients with posttreatment chronic Lyme disease. J Infect Dis. 2005 Sep 15; 192(6):1010-3. PMID: 16107953.
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    25. Drazen JM, Klempner MS. Disaster, water, cholera, vaccines, and hope. N Engl J Med. 2005 Feb 24; 352(8):827. PMID: 15728816.
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    26. Premasiri WR, Moir DT, Klempner MS, Krieger N, Jones G, Ziegler LD. Characterization of the surface enhanced raman scattering (SERS) of bacteria. J Phys Chem B. 2005 Jan 13; 109(1):312-20. PMID: 16851017.
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    27. Fleming RV, Marques AR, Klempner MS, Schmid CH, Dally LG, Martin DS, Philipp MT. Pre-treatment and post-treatment assessment of the C(6) test in patients with persistent symptoms and a history of Lyme borreliosis. Eur J Clin Microbiol Infect Dis. 2004 Aug; 23(8):615-8. PMID: 15243815.
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    28. Klempner MS, Shapiro DS. Crossing the species barrier--one small step to man, one giant leap to mankind. N Engl J Med. 2004 Mar 18; 350(12):1171-2. PMID: 14985471.
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    29. Wang XG, Kidder JM, Scagliotti JP, Klempner MS, Noring R, Hu LT. Analysis of differences in the functional properties of the substrate binding proteins of the Borrelia burgdorferi oligopeptide permease (Opp) operon. J Bacteriol. 2004 Jan; 186(1):51-60. PMID: 14679224.
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    30. Zhao Z, Chang H, Trevino RP, Whren K, Bhawan J, Klempner MS. Selective up-regulation of matrix metalloproteinase-9 expression in human erythema migrans skin lesions of acute lyme disease. J Infect Dis. 2003 Oct 15; 188(8):1098-104. PMID: 14551878.
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    31. Kaplan RF, Trevino RP, Johnson GM, Levy L, Dornbush R, Hu LT, Evans J, Weinstein A, Schmid CH, Klempner MS. Cognitive function in post-treatment Lyme disease: do additional antibiotics help? Neurology. 2003 Jun 24; 60(12):1916-22. PMID: 12821733.
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    32. Klempner MS. Controlled trials of antibiotic treatment in patients with post-treatment chronic Lyme disease. Vector Borne Zoonotic Dis. 2002; 2(4):255-63. PMID: 12804167.
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    33. Klempner MS, Hu LT, Evans J, Schmid CH, Johnson GM, Trevino RP, Norton D, Levy L, Wall D, McCall J, Kosinski M, Weinstein A. Two controlled trials of antibiotic treatment in patients with persistent symptoms and a history of Lyme disease. N Engl J Med. 2001 Jul 12; 345(2):85-92. PMID: 11450676.
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    34. Lin B, Kidder JM, Noring R, Steere AC, Klempner MS, Hu LT. Differences in synovial fluid levels of matrix metalloproteinases suggest separate mechanisms of pathogenesis in Lyme arthritis before and after antibiotic treatment. J Infect Dis. 2001 Jul 15; 184(2):174-80. PMID: 11424014.
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    35. Klempner MS, Schmid CH, Hu L, Steere AC, Johnson G, McCloud B, Noring R, Weinstein A. Intralaboratory reliability of serologic and urine testing for Lyme disease. Am J Med. 2001 Feb 15; 110(3):217-9. PMID: 11182109.
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    36. Lin B, Short SA, Eskildsen M, Klempner MS, Hu LT. Functional testing of putative oligopeptide permease (Opp) proteins of Borrelia burgdorferi: a complementation model in opp(-) Escherichia coli. Biochim Biophys Acta. 2001 Jan 15; 1499(3):222-31. PMID: 11341969.
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    37. Hu LT, Klempner MS. Update on the prevention, diagnosis, and treatment of Lyme disease. Adv Intern Med. 2001; 46:247-75. PMID: 11270961.
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    38. Klempner M. Navigating life review interviews with survivors of trauma. Oral Hist Rev. 2000 Summer-Fall; 27(2):67-83. PMID: 11640194.
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    39. Lin B, Noring R, Steere AC, Klempner MS, Hu LT. Soluble CD14 levels in the serum, synovial fluid, and cerebrospinal fluid of patients with various stages of Lyme disease. J Infect Dis. 2000 Mar; 181(3):1185-8. PMID: 10720552.
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    40. Perides G, Tanner-Brown LM, Eskildsen MA, Klempner MS. Borrelia burgdorferi induces matrix metalloproteinases by neural cultures. J Neurosci Res. 1999 Dec 15; 58(6):779-90. PMID: 10583909.
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    41. Klempner MS, Huber BT. Is it thee or me?--autoimmunity in Lyme disease. Nat Med. 1999 Dec; 5(12):1346-7. PMID: 10581067.
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    42. Klempner MS. Beyond us versus them. J Gen Intern Med. 1999 Aug; 14(8):514-5. PMID: 10491238.
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    43. Bozza M, Kyvelos D, Trepicchio WL, Collins M, Klempner MS, Dorner AJ. Recombinant human interleukin-11 does not affect functions of purified human neutrophils in vitro. J Interferon Cytokine Res. 1998 Oct; 18(10):889-95. PMID: 9809625.
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    44. Sigal LH, Zahradnik JM, Lavin P, Patella SJ, Bryant G, Haselby R, Hilton E, Kunkel M, Adler-Klein D, Doherty T, Evans J, Molloy PJ, Seidner AL, Sabetta JR, Simon HJ, Klempner MS, Mays J, Marks D, Malawista SE. A vaccine consisting of recombinant Borrelia burgdorferi outer-surface protein A to prevent Lyme disease. Recombinant Outer-Surface Protein A Lyme Disease Vaccine Study Consortium. N Engl J Med. 1998 Jul 23; 339(4):216-22. PMID: 9673299.
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    45. McDermott DF, Trehu EG, Mier JW, Sorce D, Rand W, Ronayne L, Kappler K, Clancy M, Klempner M, Atkins MB. A two-part phase I trial of high-dose interleukin 2 in combination with soluble (Chinese hamster ovary) interleukin 1 receptor. Clin Cancer Res. 1998 May; 4(5):1203-13. PMID: 9607578.
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    46. Joiner KA, Powderly WG, Blaser MJ, Klempner MS, Locksley RM, Mandell GL, Preheim LC, Remington JS, Slama TG, Steigbigel NH, Bartlett JG. Fellowship training in infectious diseases: a report from the regional and national meetings of infectious diseases division chiefs and program directors. Clin Infect Dis. 1998 May; 26(5):1060-5. PMID: 9597224.
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    47. Friedberg MH, Glantz MJ, Klempner MS, Cole BF, Perides G. Specific matrix metalloproteinase profiles in the cerebrospinal fluid correlated with the presence of malignant astrocytomas, brain metastases, and carcinomatous meningitis. Cancer. 1998 Mar 1; 82(5):923-30. PMID: 9486583.
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    48. Perides G, Charness ME, Tanner LM, Péter O, Satz N, Steere AC, Klempner MS. Matrix metalloproteinases in the cerebrospinal fluid of patients with Lyme neuroborreliosis. J Infect Dis. 1998 Feb; 177(2):401-8. PMID: 9466528.
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    49. Hu LT, Pratt SD, Perides G, Katz L, Rogers RA, Klempner MS. Isolation, cloning, and expression of a 70-kilodalton plasminogen binding protein of Borrelia burgdorferi. Infect Immun. 1997 Dec; 65(12):4989-95. PMID: 9393787.
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    50. Hu LT, Klempner MS. Host-pathogen interactions in the immunopathogenesis of Lyme disease. J Clin Immunol. 1997 Sep; 17(5):354-65. PMID: 9327334.
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    51. Hu LT, Perides G, Tanner LM, Klempner MS. Detection of a 130-kD matrix metalloproteinase in cerebrospinal fluid from a patient with Lyme neuroborreliosis. Clin Infect Dis. 1997 Jun; 24(6):1276-7. PMID: 9195108.
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    52. Du Bois JS, Trehu EG, Mier JW, Shapiro L, Epstein M, Klempner M, Dinarello C, Kappler K, Ronayne L, Rand W, Atkins MB. Randomized placebo-controlled clinical trial of high-dose interleukin-2 in combination with a soluble p75 tumor necrosis factor receptor immunoglobulin G chimera in patients with advanced melanoma and renal cell carcinoma. J Clin Oncol. 1997 Mar; 15(3):1052-62. PMID: 9060545.
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    53. Trehu EG, Mier JW, Dubois JS, Sorce D, Klempner MS, Epstein M, Dinarello CA, Shapiro L, Kappler K, Ronayne L, Atkins MB. Phase I trial of interleukin 2 in combination with the soluble tumor necrosis factor receptor p75 IgG chimera. Clin Cancer Res. 1996 Aug; 2(8):1341-51. PMID: 9816306.
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    54. Klempner MS, Noring R, Epstein MP, McCloud B, Rogers RA. Binding of human urokinase type plasminogen activator and plasminogen to Borrelia species. J Infect Dis. 1996 Jul; 174(1):97-104. PMID: 8656020.
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    55. Falagas ME, Klempner MS. Babesiosis in patients with AIDS: a chronic infection presenting as fever of unknown origin. Clin Infect Dis. 1996 May; 22(5):809-12. PMID: 8722936.
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    56. Perides G, Noring R, Klempner MS. Inhibition of Borrelia burgdorferi-bound fibrinolytic enzymes by alpha2-antiplasmin, PAI-1 and PAI-2. Biochem Biophys Res Commun. 1996 Feb 27; 219(3):690-5. PMID: 8645243.
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    57. Hu LT, Perides G, Noring R, Klempner MS. Binding of human plasminogen to Borrelia burgdorferi. Infect Immun. 1995 Sep; 63(9):3491-6. PMID: 7642282.
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    58. Klempner MS, Langdon LO. Training in infectious disease: planning for the future. Infect Agents Dis. 1995 Jun; 4(2):110-4. PMID: 7613728.
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    59. Klempner MS, Noring R, Epstein MP, McCloud B, Hu R, Limentani SA, Rogers RA. Binding of human plasminogen and urokinase-type plasminogen activator to the Lyme disease spirochete, Borrelia burgdorferi. J Infect Dis. 1995 May; 171(5):1258-65. PMID: 7751701.
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    60. Stone DR, Estes NA, Klempner MS. Mycobacterium bovis infection of an implantable defibrillator following intravesical therapy with bacille Calmette-Guérin. Clin Infect Dis. 1993 Jun; 16(6):825-6. PMID: 8329515.
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    61. Klempner MS, Noring R, Rogers RA. Invasion of human skin fibroblasts by the Lyme disease spirochete, Borrelia burgdorferi. J Infect Dis. 1993 May; 167(5):1074-81. PMID: 8486939.
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    62. Georgilis K, Peacocke M, Klempner MS. Fibroblasts protect the Lyme disease spirochete, Borrelia burgdorferi, from ceftriaxone in vitro. J Infect Dis. 1992 Aug; 166(2):440-4. PMID: 1634816.
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    63. Katzen NA, Segal GM, Vannier E, Nerad JL, Klempner MS, Dinarello CA. Comparison of granulocyte-macrophage colony stimulating factor and interleukin-1 production from human peripheral blood mononuclear cells as measured by specific radioimmunoassays. Eur Cytokine Netw. 1992 Jul-Aug; 3(4):365-72. PMID: 1421010.
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    64. Schapiro BL, Newburger PE, Klempner MS, Dinauer MC. Chronic granulomatous disease presenting in a 69-year-old man. N Engl J Med. 1991 Dec 19; 325(25):1786-90. PMID: 1719419.
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    65. Georgilis K, Noring R, Steere AC, Klempner MS. Neutrophil chemotactic factors in synovial fluids of patients with Lyme disease. Arthritis Rheum. 1991 Jun; 34(6):770-5. PMID: 2053924.
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    66. Georgilis K, Steere AC, Klempner MS. Infectivity of Borrelia burgdorferi correlates with resistance to elimination by phagocytic cells. J Infect Dis. 1991 Jan; 163(1):150-5. PMID: 1984461.
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    67. Mier JW, Vachino G, Klempner MS, Aronson FR, Noring R, Smith S, Brandon EP, Laird W, Atkins MB. Inhibition of interleukin-2-induced tumor necrosis factor release by dexamethasone: prevention of an acquired neutrophil chemotaxis defect and differential suppression of interleukin-2-associated side effects. Blood. 1990 Nov 15; 76(10):1933-40. PMID: 2242421.
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    68. Lindler LE, Klempner MS, Straley SC. Yersinia pestis pH 6 antigen: genetic, biochemical, and virulence characterization of a protein involved in the pathogenesis of bubonic plague. Infect Immun. 1990 Aug; 58(8):2569-77. PMID: 2164509.
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    69. Klempner MS, Noring R, Mier JW, Atkins MB. An acquired chemotactic defect in neutrophils from patients receiving interleukin-2 immunotherapy. N Engl J Med. 1990 Apr 5; 322(14):959-65. PMID: 2156163.
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    70. Endres S, Ghorbani R, Kelley VE, Georgilis K, Lonnemann G, van der Meer JW, Cannon JG, Rogers TS, Klempner MS, Weber PC, et al. The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. N Engl J Med. 1989 Feb 2; 320(5):265-71. PMID: 2783477.
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    71. Klempner MS, Styrt B. Prevention of recurrent staphylococcal skin infections with low-dose oral clindamycin therapy. JAMA. 1988 Nov 11; 260(18):2682-5. PMID: 3184334.
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    72. Georgilis K, Klempner MS. In vitro effects of omega-3 fatty acids on neutrophil intracellular calcium homeostasis and receptor expression for FMLP and LTB4. Inflammation. 1988 Oct; 12(5):475-90. PMID: 2848770.
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    73. Styrt B, Schwartz MA, Klempner MS. Calcium release associated with discharge of specific granule contents from human neutrophils. Biochem Biophys Res Commun. 1988 Aug 15; 154(3):1308-13. PMID: 3408500.
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    74. Styrt B, Pollack CR, Klempner MS. An abnormal calcium uptake pump in Chediak-Higashi neutrophil lysosomes. J Leukoc Biol. 1988 Aug; 44(2):130-5. PMID: 2457062.
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    75. Styrt B, Klempner MS, Rocklin RE. Comparison of prostaglandins E2 and D2 as inhibitors of respiratory burst in neutrophils from atopic and nonatopic subjects. Inflammation. 1988 Jun; 12(3):213-21. PMID: 2843463.
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    76. Ho JL, Klempner MS. Diminished activity of protein kinase C in tetanus toxin-treated macrophages and in the spinal cord of mice manifesting generalized tetanus intoxication. J Infect Dis. 1988 May; 157(5):925-33. PMID: 3283262.
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    77. Styrt B, Klempner MS. Lysosomotropic amines modulate neutrophil calcium homeostasis. J Cell Physiol. 1988 May; 135(2):309-16. PMID: 3372598.
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    78. Styrt B, Klempner MS. Effects of pH on killing of Staphylococcus aureus and Escherichia coli by constituents of the neutrophil phagolysosome. J Med Microbiol. 1988 Feb; 25(2):101-7. PMID: 3276896.
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    79. Styrt B, Klempner MS. Lysosomotropic behavior of adrenergic antagonists in interactions with human neutrophils. Biochem Pharmacol. 1988 Feb 1; 37(3):435-41. PMID: 2892495.
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    80. Styrt B, Rocklin RE, Klempner MS. Characterization of the neutrophil respiratory burst in atopy. J Allergy Clin Immunol. 1988 Jan; 81(1):20-6. PMID: 2828450.
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    81. Styrt B, Schwartz MA, Klempner MS. Linkage between neutrophil degranulation and calcium discharge. Biochem Biophys Res Commun. 1987 Aug 14; 146(3):1386-91. PMID: 3619936.
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    82. Georgilis K, Schaefer C, Dinarello CA, Klempner MS. Human recombinant interleukin 1 beta has no effect on intracellular calcium or on functional responses of human neutrophils. J Immunol. 1987 May 15; 138(10):3403-7. PMID: 3033074.
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    83. Dana N, Styrt B, Griffin JD, Todd RF, Klempner MS, Arnaout MA. Two functional domains in the phagocyte membrane glycoprotein Mo1 identified with monoclonal antibodies. J Immunol. 1986 Nov 15; 137(10):3259-63. PMID: 2430017.
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    84. Borish L, O'Reilly D, Klempner MS, Rocklin RE. Leukocyte inhibitory factor (LIF) potentiates neutrophil responses to formyl-methionyl-leucyl-phenylalanine. J Immunol. 1986 Sep 15; 137(6):1897-903. PMID: 3018081.
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    85. Pollack C, Straley SC, Klempner MS. Probing the phagolysosomal environment of human macrophages with a Ca2+-responsive operon fusion in Yersinia pestis. Nature. 1986 Aug 28-Sep 3; 322(6082):834-6. PMID: 3748170.
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    86. Ho JL, Klempner MS. Inhibition of macrophage secretion by tetanus toxin is not directly linked to cytosolic calcium homeostasis. Biochem Biophys Res Commun. 1986 Feb 26; 135(1):16-24. PMID: 3954764.
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    87. Styrt B, Klempner MS. Inhibition of neutrophil oxidative metabolism by lysosomotropic weak bases. Blood. 1986 Feb; 67(2):334-42. PMID: 3002523.
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    88. Ho JL, Klempner MS. In vitro evaluation of clindamycin in combination with oxacillin, rifampin, or vancomycin against Staphylococcus aureus. Diagn Microbiol Infect Dis. 1986 Feb; 4(2):133-8. PMID: 3956136.
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    89. Ho JL, Klempner MS. Tetanus toxin inhibits secretion of lysosomal contents from human macrophages. J Infect Dis. 1985 Nov; 152(5):922-9. PMID: 3930628.
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    90. Styrt B, Klempner MS. Modification of interactions between neutrophils and staphylococci by lysosomotropic weak bases. Infect Immun. 1985 Nov; 50(2):415-9. PMID: 2997038.
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    91. Styrt B, Rocklin RE, Klempner MS. Inhibition of neutrophil superoxide production by fanetizole. Inflammation. 1985 Sep; 9(3):233-44. PMID: 2995253.
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    92. Styrt B, Johnson PC, Klempner MS. Differential lysis of plasma membranes and granules of human neutrophils by digitonin. Tissue Cell. 1985; 17(6):793-800. PMID: 4089860.
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    93. Styrt B, Klempner MS. Late-presenting variant of chronic granulomatous disease. Pediatr Infect Dis. 1984 Nov-Dec; 3(6):556-9. PMID: 6514594.
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    94. Styrt B, Klempner MS. Leukocyte uptake of daunomycin. Drug Metab Dispos. 1984 Nov-Dec; 12(6):790-1. PMID: 6150833.
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    95. Klempner MS. Interactions of polymorphonuclear leukocytes with anaerobic bacteria. Rev Infect Dis. 1984 Mar-Apr; 6 Suppl 1:S40-4. PMID: 6372036.
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    96. Lad PM, Glovsky MM, Smiley PA, Klempner M, Reisinger DM, Richards JH. The beta-adrenergic receptor in the human neutrophil plasma membrane: receptor-cyclase uncoupling is associated with amplified GTP activation. J Immunol. 1984 Mar; 132(3):1466-71. PMID: 6319494.
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    97. Klempner MS, Styrt B. Alkalinizing the intralysosomal pH inhibits degranulation of human neutrophils. J Clin Invest. 1983 Nov; 72(5):1793-800. PMID: 6415117.
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    98. Klempner MS, Styrt B. Alkalinization of the intralysosomal pH by clindamycin and its effects on neutrophil function. J Antimicrob Chemother. 1983 Oct; 12 Suppl C:39-50. PMID: 6315671.
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    99. Klempner MS, Cendron M, Wyler DJ. Attachment of plasma membrane vesicles of human macrophages to Leishmania tropica promastigotes. J Infect Dis. 1983 Sep; 148(3):377-84. PMID: 6619572.
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    100. Klempner MS, Rocklin RE. Effects of leukocyte inhibitory factor (LIF) on human neutrophil function. Inflammation. 1983 Jun; 7(2):145-53. PMID: 6305834.
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    101. Styrt B, Klempner MS. Internal pH of human neutrophil lysosomes. FEBS Lett. 1982 Nov 22; 149(1):113-6. PMID: 6185362.
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    102. Klempner MS, Rocklin RE. Specific binding of leukocyte inhibitory factor to neutrophil plasma membranes. J Immunol. 1982 May; 128(5):2040-3. PMID: 7037959.
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    103. Tonnesen MG, Klempner MS, Austen KF, Wintroub BU. Identification of a human neutrophil angiotension II-generating protease as cathepsin G. J Clin Invest. 1982 Jan; 69(1):25-30. PMID: 6172448.
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    104. Simon GL, Klempner MS, Kasper DL, Gorbach SL. Alterations in opsonophagocytic killing by neutrophils of Bacteroides fragilis associated with animal and laboratory passage: effect of capsular polysaccharide. J Infect Dis. 1982 Jan; 145(1):72-7. PMID: 7054319.
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    105. Victor M, Weiss J, Klempner MS, Elsbach P. Phospholipase A2 activity in the plasma membrane of human polymorphonuclear leukocytes. FEBS Lett. 1981 Dec 28; 136(2):298-300. PMID: 7327265.
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    106. Klempner MS, Styrt B. Clindamycin uptake by human neutrophils. J Infect Dis. 1981 Nov; 144(5):472-9. PMID: 6171600.
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    107. Klempner MS, Mikkelsen RB, Corfman DH, André-Schwartz J. Neutrophil plasma membranes. I. High-yield purification of human neutrophil plasma membrane vesicles by nitrogen cavitation and differential centrifugation. J Cell Biol. 1980 Jul; 86(1):21-8. PMID: 7419575.
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    108. Crowley CA, Curnutte JT, Rosin RE, André-Schwartz J, Gallin JI, Klempner M, Snyderman R, Southwick FS, Stossel TP, Babior BM. An inherited abnormality of neutrophil adhesion. Its genetic transmission and its association with a missing protein. N Engl J Med. 1980 May 22; 302(21):1163-8. PMID: 7366657.
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    109. Klempner MS, Gallin JI, Balow JE, Van Kammen DP. The effect of hemodialysis and C5a des arg on neutrophil subpopulations. Blood. 1980 May; 55(5):777-83. PMID: 7362869.
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    110. Gallin JI, Wright DG, Malech HL, Davis JM, Klempner MS, Kirkpatrick CH. Disorders of phagocyte chemotaxis. Ann Intern Med. 1980 Apr; 92(4):520-38. PMID: 6987931.
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    111. Klempner MS, Dinarello CA, Henderson WR, Gallin JI. Stimulation of neutrophil oxygen-dependent metabolism by human leukocytic pyrogen. J Clin Invest. 1979 Oct; 64(4):996-1002. PMID: 90061.
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    112. Parrillo JE, Borst GC, Mazur MH, Iannini P, Klempner MS, Moellering RC, Anderson SE. Endocarditis due to resistant viridans streptococci during oral penicillin chemoprophylaxis. N Engl J Med. 1979 Feb 8; 300(6):296-300. PMID: 252640.
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    113. Klempner MS, Gallin JI. Inhibition of neutrophil Fc receptor function by cotricosteroids. Clin Exp Immunol. 1978 Oct; 34(1):137-42. PMID: 750117.
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    114. Klempner MS, Dinarello CA, Gallin JI. Human leukocytic pyrogen induces release of specific granule contents from human neutrophils. J Clin Invest. 1978 May; 61(5):1330-6. PMID: 659595.
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    115. Klempner MS, Gallin JI. Separation and functional characterization of human neutrophil subpopulations. Blood. 1978 Apr; 51(4):659-69. PMID: 564724.
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    116. Sergent JS, Lockshin MD, Klempner MS, Lipsky BA. Central nervous system disease in systemic lupus erythematosus. Therapy and prognosis. Am J Med. 1975 May; 58(5):644-54. PMID: 1130420.
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