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Institution

Garry Handelman B.A, PhD

Title
InstitutionUniversity of Massachusetts Lowell
DepartmentClinicalLab & NutritionalSci
AddressWeed Hall, Room 103
Lowell, MA 01854
Phone978-934-4503
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Raimann JG, Abbas SR, Liu L, Larive B, Beck G, Kotanko P, Levin NW, Handelman G. The effect of increased frequency of hemodialysis on vitamin C concentrations: an ancillary study of the randomized Frequent Hemodialysis Network (FHN) daily trial. BMC Nephrol. 2019 May 17; 20(1):179. PMID: 31101018.
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    2. Madero M, Cano KB, Campos I, Tao X, Maheshwari V, Brown J, Cornejo B, Handelman G, Thijssen S, Kotanko P. Removal of Protein-Bound Uremic Toxins during Hemodialysis Using a Binding Competitor. Clin J Am Soc Nephrol. 2019 Feb 12. PMID: 30755453.
      View in: PubMed
    3. Malhotra R, Persic V, Zhang W, Brown J, Tao X, Rosales L, Thijssen S, Finkelstein FO, Unruh ML, Ikizler A, Garimella PS, Ix JH, Kooman J, Levin NW, Handelman GJ, Kotanko P. Tryptophan and Kynurenine Levels and Its Association With Sleep, Nonphysical Fatigue, and Depression in Chronic Hemodialysis Patients. J Ren Nutr. 2017 Mar 30. PMID: 28366444.
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    4. Seibert E, Richter A, Kuhlmann MK, Wang S, Levin NW, Kotanko P, Handelman GJ. Plasma vitamin C levels in ESRD patients and occurrence of hypochromic erythrocytes. Hemodial Int. 2016 Sep 12. PMID: 27619554.
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    5. Liu Y, Weisberg LS, Langman CB, Logan A, Hunter K, Prasad D, Avila J, Venkatchalam T, Berns JS, Handelman GJ, Sirover WD. Plasma oxalate levels in prevalent hemodialysis patients and potential implications for ascorbic acid supplementation. Clin Biochem. 2016 Oct; 49(15):1133-1139. PMID: 27265723.
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    6. Tao X, Thijssen S, Kotanko P, Ho CH, Henrie M, Stroup E, Handelman G. Improved dialytic removal of protein-bound uraemic toxins with use of albumin binding competitors: an in vitro human whole blood study. Sci Rep. 2016; 6:23389. PMID: 27001248.
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    7. Rozati M, Barnett J, Wu D, Handelman G, Saltzman E, Wilson T, Li L, Wang J, Marcos A, Ordovás JM, Lee YC, Meydani M, Meydani SN. Cardio-metabolic and immunological impacts of extra virgin olive oil consumption in overweight and obese older adults: a randomized controlled trial. Nutr Metab (Lond). 2015; 12:28. PMID: 26251666.
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    8. Tao X, Thijssen S, Levin N, Kotanko P, Handelman G. Enhanced Indoxyl Sulfate Dialyzer Clearance with the Use of Binding Competitors. Blood Purif. 2015; 39(4):323-30. PMID: 25998324.
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    9. Sirover WD, Liu Y, Logan A, Hunter K, Benz RL, Prasad D, Avila J, Venkatchalam T, Weisberg LS, Handelman GJ. Plasma ascorbic acid concentrations in prevalent patients with end-stage renal disease on hemodialysis. J Ren Nutr. 2015 May; 25(3):292-300. PMID: 25455040.
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    10. Tao X, Hoenich N, Handelman SK, Levin NW, Kotanko P, Handelman GJ. Transfer of low-molecular weight single-stranded DNA through the membrane of a high-flux dialyzer. Int J Artif Organs. 2014 Jul 31; 37(7):529-38. PMID: 25044384.
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    11. Handelman GJ. Reply: To PMID 23689318. Blood Purif. 2014; 37(1):47. PMID: 24779039.
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    12. Handelman GJ, Kotanko P, Cisternas MG, Hoenich N, Usvyat L, Kuhlmann M, Levin NW. Hospitalization and mortality in hemodialysis patients: association with hemoglobin variability. Blood Purif. 2013; 35(4):247-57. PMID: 23689318.
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    13. Raimann JG, Levin NW, Craig RG, Sirover W, Kotanko P, Handelman G. Is vitamin C intake too low in dialysis patients? Semin Dial. 2013 Jan-Feb; 26(1):1-5. PMID: 23106569.
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    14. Kilonzo KG, Ghosh S, Temu SA, Maro V, Callegari J, Carter M, Handelman G, Finkelstein FO, Levin N, Yeates K. Outcome of acute peritoneal dialysis in northern Tanzania. Perit Dial Int. 2012 May-Jun; 32(3):261-6. PMID: 22641736.
      View in: PubMed
    15. Callegari JG, Kilonzo KG, Yeates KE, Handelman GJ, Finkelstein FO, Kotanko P, Levin NW, Carter M. Peritoneal dialysis for acute kidney injury in sub-Saharan Africa: challenges faced and lessons learned at Kilimanjaro Christian Medical Centre. Kidney Int. 2012 Feb; 81(4):331-3. PMID: 22289791.
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    16. Ockene IS, Tellez TL, Rosal MC, Reed GW, Mordes J, Merriam PA, Olendzki BC, Handelman G, Nicolosi R, Ma Y. Outcomes of a Latino community-based intervention for the prevention of diabetes: the Lawrence Latino Diabetes Prevention Project. Am J Public Health. 2012 Feb; 102(2):336-42. PMID: 22390448.
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    17. Zhu F, Kotanko P, Handelman GJ, Raimann JG, Liu L, Carter M, Kuhlmann MK, Seibert E, Leonard EF, Levin NW. Estimation of normal hydration in dialysis patients using whole body and calf bioimpedance analysis. Physiol Meas. 2011 Jul; 32(7):887-902. PMID: 21646705.
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    18. Kruse A, Tao X, Bhalani V, Handelman G, Levin NW, Kotanko P, Thijssen S. Clearance of p-cresol sulfate and ß-2-microglobulin from dialysate by commercially available sorbent technology. ASAIO J. 2011 May-Jun; 57(3):219-24. PMID: 21499073.
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    19. Handelman GJ, Levin NW. Guidelines for vitamin supplements in chronic kidney disease patients: what is the evidence? J Ren Nutr. 2011 Jan; 21(1):117-9. PMID: 21195933.
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    20. Handelman GJ. New insight on vitamin C in patients with chronic kidney disease. J Ren Nutr. 2011 Jan; 21(1):110-2. PMID: 21195931.
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    21. Handelman GJ, Levin NW. Red cell survival: relevance and mechanism involved. J Ren Nutr. 2010 Sep; 20(5 Suppl):S84-8. PMID: 20797578.
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    22. Finkelstein FO, Juergensen P, Wang S, Santacroce S, Levine M, Kotanko P, Levin NW, Handelman GJ. Hemoglobin and plasma vitamin C levels in patients on peritoneal dialysis. Perit Dial Int. 2011 Jan-Feb; 31(1):74-9. PMID: 20558814.
      View in: PubMed
    23. Megdal PA, Siemsen D, Sands D, Dratz EA, Handelman GJ. Facile fingerstick insulin analysis: Application to monitoring postprandial insulin responses to snack foods. J Diabetes. 2010 Mar; 2(1):28-35. PMID: 20923472.
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    24. Megdal PA, Craft NA, Handelman GJ. A simplified method to distinguish farmed (Salmo salar) from wild salmon: fatty acid ratios versus astaxanthin chiral isomers. Lipids. 2009 Jun; 44(6):569-76. PMID: 19452184.
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    25. Carter M, Zhu F, Kotanko P, Kuhlmann M, Ramirez L, Heymsfield SB, Handelman G, Levin NW. Assessment of body composition in dialysis patients by arm bioimpedance compared to MRI and 40K measurements. Blood Purif. 2009; 27(4):330-7. PMID: 19270452.
      View in: PubMed
    26. Handelman GJ, Megdal PA, Handelman SK. Bacterial DNA in water and dialysate: detection and significance for patient outcomes. Blood Purif. 2009; 27(1):81-5. PMID: 19169023.
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    27. Handelman GJ, Levin NW. Iron and anemia in human biology: a review of mechanisms. Heart Fail Rev. 2008 Dec; 13(4):393-404. PMID: 18363095.
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    28. Richter A, Kuhlmann MK, Seibert E, Kotanko P, Levin NW, Handelman GJ. Vitamin C deficiency and secondary hyperparathyroidism in chronic haemodialysis patients. Nephrol Dial Transplant. 2008 Jun; 23(6):2058-63. PMID: 18353890.
      View in: PubMed
    29. Handelman GJ. Newer strategies for anemia prevention in hemodialysis. Int J Artif Organs. 2007 Nov; 30(11):1014-9. PMID: 18067104.
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    30. Levin NW, Handelman GJ, Coresh J, Port FK, Kaysen GA. Reverse epidemiology: a confusing, confounding, and inaccurate term. Semin Dial. 2007 Nov-Dec; 20(6):586-92. PMID: 17991209.
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    31. Wang S, Geraci G, Kuhlmann MK, Levin NW, Handelman GJ. Chemical reactions of vitamin C with intravenous-iron formulations. Nephrol Dial Transplant. 2008 Jan; 23(1):120-5. PMID: 17951305.
      View in: PubMed
    32. Handelman G, Kotanko P, Levin NW. Mechanisms of hypertension. N Engl J Med. 2007 Aug 23; 357(8):827-9; author reply 827-9. PMID: 17717862.
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    33. Handelman GJ. Vitamin C neglect in hemodialysis: sailing between Scylla and Charybdis. Blood Purif. 2007; 25(1):58-61. PMID: 17170539.
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    34. Gotch F, Kotanko P, Handelman G, Levin N. A kinetic model of calcium mass balance during dialysis therapy. Blood Purif. 2007; 25(1):139-49. PMID: 17170552.
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    35. Handelman GJ. Vitamin C deficiency in dialysis patients--are we perceiving the tip of an iceberg? Nephrol Dial Transplant. 2007 Feb; 22(2):328-31. PMID: 17107966.
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    36. Wenzel AJ, Gerweck C, Barbato D, Nicolosi RJ, Handelman GJ, Curran-Celentano J. A 12-wk egg intervention increases serum zeaxanthin and macular pigment optical density in women. J Nutr. 2006 Oct; 136(10):2568-73. PMID: 16988128.
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    37. Goodrow EF, Wilson TA, Houde SC, Vishwanathan R, Scollin PA, Handelman G, Nicolosi RJ. Consumption of one egg per day increases serum lutein and zeaxanthin concentrations in older adults without altering serum lipid and lipoprotein cholesterol concentrations. J Nutr. 2006 Oct; 136(10):2519-24. PMID: 16988120.
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    38. Handelman GJ. Debate forum: carnitine supplements have not been demonstrated as effective in patients on long-term dialysis therapy. Blood Purif. 2006; 24(1):140-2. PMID: 16361854.
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    39. van der Sande FM, Rosales LM, Brener Z, Kooman JP, Kuhlmann M, Handelman G, Greenwood RN, Carter M, Schneditz D, Leunissen KM, Levin NW. Effect of ultrafiltration on thermal variables, skin temperature, skin blood flow, and energy expenditure during ultrapure hemodialysis. J Am Soc Nephrol. 2005 Jun; 16(6):1824-31. PMID: 15857923.
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    40. Nicolosi RJ, Woolfrey B, Wilson TA, Scollin P, Handelman G, Fisher R. Decreased aortic early atherosclerosis and associated risk factors in hypercholesterolemic hamsters fed a high- or mid-oleic acid oil compared to a high-linoleic acid oil. J Nutr Biochem. 2004 Sep; 15(9):540-7. PMID: 15350986.
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    41. Alexaki A, Wilson TA, Atallah MT, Handelman G, Nicolosi RJ. Hamsters fed diets high in saturated fat have increased cholesterol accumulation and cytokine production in the aortic arch compared with cholesterol-fed hamsters with moderately elevated plasma non-HDL cholesterol concentrations. J Nutr. 2004 Feb; 134(2):410-5. PMID: 14747681.
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    42. Handelman GJ. Efforts to determine the role of oxidant stress in dialysis outcomes. Semin Dial. 2003 Nov-Dec; 16(6):488-91. PMID: 14629612.
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    43. Saran R, Novak JE, Desai A, Abdulhayoglu E, Warren JS, Bustami R, Handelman GJ, Barbato D, Weitzel W, D'Alecy LG, Rajagopalan S. Impact of vitamin E on plasma asymmetric dimethylarginine (ADMA) in chronic kidney disease (CKD): a pilot study. Nephrol Dial Transplant. 2003 Nov; 18(11):2415-20. PMID: 14551376.
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    44. Handelman GJ, Rosales LM, Barbato D, Luscher J, Adhikarla R, Nicolosi RJ, Finkelstein FO, Ronco C, Kaysen GA, Hoenich NA, Levin NW. Breath ethane in dialysis patients and control subjects. Free Radic Biol Med. 2003 Jul 1; 35(1):17-23. PMID: 12826252.
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    45. Yoganathan S, Nicolosi R, Wilson T, Handelman G, Scollin P, Tao R, Binford P, Orthoefer F. Antagonism of croton oil inflammation by topical emu oil in CD-1 mice. Lipids. 2003 Jun; 38(6):603-7. PMID: 12934669.
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    46. Handelman GJ. Current studies on oxidant stress in dialysis. Blood Purif. 2003; 21(1):46-50. PMID: 12566661.
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    47. Nicolosi RJ, Wilson TA, Handelman G, Foxall T, Keaney JF, Vita JA. Decreased aortic early atherosclerosis in hypercholesterolemic hamsters fed oleic acid-rich TriSun oil compared to linoleic acid-rich sunflower oil. J Nutr Biochem. 2002 Jul; 13(7):392-402. PMID: 12121826.
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    48. Spittle MA, Hoenich NA, Handelman GJ, Adhikarla R, Homel P, Levin NW. Oxidative stress and inflammation in hemodialysis patients. Am J Kidney Dis. 2001 Dec; 38(6):1408-13. PMID: 11728983.
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    49. Nicolosi RJ, Wilson TA, Lawton C, Handelman GJ. Dietary effects on cardiovascular disease risk factors: beyond saturated fatty acids and cholesterol. J Am Coll Nutr. 2001 Oct; 20(5 Suppl):421S-427S; discussion 440S-442S. PMID: 11603652.
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    50. Handelman GJ. The evolving role of carotenoids in human biochemistry. Nutrition. 2001 Oct; 17(10):818-22. PMID: 11684387.
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    51. Handelman GJ, Walter MF, Adhikarla R, Gross J, Dallal GE, Levin NW, Blumberg JB. Elevated plasma F2-isoprostanes in patients on long-term hemodialysis. Kidney Int. 2001 May; 59(5):1960-6. PMID: 11318969.
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    52. Nightingale ZD, Lancha AH, Handelman SK, Dolnikowski GG, Busse SC, Dratz EA, Blumberg JB, Handelman GJ. Relative reactivity of lysine and other peptide-bound amino acids to oxidation by hypochlorite. Free Radic Biol Med. 2000 Sep 1; 29(5):425-33. PMID: 11020664.
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    53. Walter MF, Blumberg JB, Dolnikowski GG, Handelman GJ. Streamlined F2-isoprostane analysis in plasma and urine with high-performance liquid chromatography and gas chromatography/mass spectroscopy. Anal Biochem. 2000 Apr 10; 280(1):73-9. PMID: 10805523.
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    54. Knutson MD, Handelman GJ, Viteri FE. Methods for measuring ethane and pentane in expired air from rats and humans. Free Radic Biol Med. 2000 Feb 15; 28(4):514-9. PMID: 10719232.
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    55. Handelman GJ. Evaluation of oxidant stress in dialysis patients. Blood Purif. 2000; 18(4):343-9. PMID: 10965079.
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    56. Handelman GJ, Cao G, Walter MF, Nightingale ZD, Paul GL, Prior RL, Blumberg JB. Antioxidant capacity of oat (Avena sativa L.) extracts. 1. Inhibition of low-density lipoprotein oxidation and oxygen radical absorbance capacity. J Agric Food Chem. 1999 Dec; 47(12):4888-93. PMID: 10606548.
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    57. Wu D, Meydani M, Leka LS, Nightingale Z, Handelman GJ, Blumberg JB, Meydani SN. Effect of dietary supplementation with black currant seed oil on the immune response of healthy elderly subjects. Am J Clin Nutr. 1999 Oct; 70(4):536-43. PMID: 10500023.
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    58. Nightingale ZD, Blumberg JB, Handelman GJ. Purification of fatty acid methyl esters by high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl. 1999 Sep 24; 732(2):495-500. PMID: 10517372.
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    59. Handelman GJ, Nightingale ZD, Lichtenstein AH, Schaefer EJ, Blumberg JB. Lutein and zeaxanthin concentrations in plasma after dietary supplementation with egg yolk. Am J Clin Nutr. 1999 Aug; 70(2):247-51. PMID: 10426702.
      View in: PubMed
    60. Handelman GJ. High-performance liquid chromatography analysis of cholesterol linoleate hydroperoxide in oxidized low density lipoproteins: calibration by conjugated diene internal standard. Methods Enzymol. 1999; 300:43-50. PMID: 9919507.
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    61. Halpner AD, Handelman GJ, Harris JM, Belmont CA, Blumberg JB. Protection by vitamin C of loss of vitamin E in cultured rat hepatocytes. Arch Biochem Biophys. 1998 Nov 15; 359(2):305-9. PMID: 9808773.
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    62. Obin M, Shang F, Gong X, Handelman G, Blumberg J, Taylor A. Redox regulation of ubiquitin-conjugating enzymes: mechanistic insights using the thiol-specific oxidant diamide. FASEB J. 1998 May; 12(7):561-9. PMID: 9576483.
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    63. Handelman GJ, Nightingale ZD, Dolnikowski GG, Blumberg JB. Formation of carbonyls during attack on insulin by submolar amounts of hypochlorite. Anal Biochem. 1998 May 1; 258(2):339-48. PMID: 9570850.
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    64. Handelman GJ. High-dose vitamin supplements for cigarette smokers: caution is indicated. Nutr Rev. 1997 Oct; 55(10):369-70. PMID: 9354081.
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    65. Taylor A, Jacques PF, Nowell T, Perrone G, Blumberg J, Handelman G, Jozwiak B, Nadler D. Vitamin C in human and guinea pig aqueous, lens and plasma in relation to intake. Curr Eye Res. 1997 Sep; 16(9):857-64. PMID: 9288446.
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    66. Haskell MJ, Handelman GJ, Peerson JM, Jones AD, Rabbi MA, Awal MA, Wahed MA, Mahalanabis D, Brown KH. Assessment of vitamin A status by the deuterated-retinol-dilution technique and comparison with hepatic vitamin A concentration in Bangladeshi surgical patients. Am J Clin Nutr. 1997 Jul; 66(1):67-74. PMID: 9209171.
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    67. Haramaki N, Han D, Handelman GJ, Tritschler HJ, Packer L. Cytosolic and mitochondrial systems for NADH- and NADPH-dependent reduction of alpha-lipoic acid. Free Radic Biol Med. 1997; 22(3):535-42. PMID: 8981046.
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    68. Mayne ST, Handelman GJ, Beecher G. Beta-Carotene and lung cancer promotion in heavy smokers--a plausible relationship? J Natl Cancer Inst. 1996 Nov 6; 88(21):1513-5. PMID: 8901847.
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    69. Handelman GJ, Packer L, Cross CE. Destruction of tocopherols, carotenoids, and retinol in human plasma by cigarette smoke. Am J Clin Nutr. 1996 Apr; 63(4):559-65. PMID: 8599320.
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    70. Handelman GJ, Epstein WL, Peerson J, Spiegelman D, Machlin LJ, Dratz EA. Human adipose alpha-tocopherol and gamma-tocopherol kinetics during and after 1 y of alpha-tocopherol supplementation. Am J Clin Nutr. 1994 May; 59(5):1025-32. PMID: 8172086.
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    71. Handelman GJ, Frankel EN, Fenz R, German JB. Chemical changes during the early phase of in vitro oxidative damage to human LDL. Biochem Mol Biol Int. 1993 Nov; 31(4):777-88. PMID: 8298506.
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    72. Handelman GJ, Haskell MJ, Jones AD, Clifford AJ. An improved protocol for determining ratios of retinol-d4 to retinol isolated from human plasma. Anal Chem. 1993 Aug 1; 65(15):2024-8. PMID: 8372966.
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    73. Meydani M, Evans WJ, Handelman G, Biddle L, Fielding RA, Meydani SN, Burrill J, Fiatarone MA, Blumberg JB, Cannon JG. Protective effect of vitamin E on exercise-induced oxidative damage in young and older adults. Am J Physiol. 1993 May; 264(5 Pt 2):R992-8. PMID: 8498608.
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    74. Meydani M, Evans W, Handelman G, Fielding RA, Meydani SN, Fiatarone MA, Blumberg JB, Cannon JG. Antioxidant response to exercise-induced oxidative stress and protection by vitamin E. Ann N Y Acad Sci. 1992 Sep 30; 669:363-4. PMID: 1444048.
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    75. Handelman GJ, Snodderly DM, Adler AJ, Russett MD, Dratz EA. Measurement of carotenoids in human and monkey retinas. Methods Enzymol. 1992; 213:220-30. PMID: 1435304.
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    76. Handelman GJ, Snodderly DM, Krinsky NI, Russett MD, Adler AJ. Biological control of primate macular pigment. Biochemical and densitometric studies. Invest Ophthalmol Vis Sci. 1991 Feb; 32(2):257-67. PMID: 1993576.
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    77. Snodderly DM, Handelman GJ, Adler AJ. Distribution of individual macular pigment carotenoids in central retina of macaque and squirrel monkeys. Invest Ophthalmol Vis Sci. 1991 Feb; 32(2):268-79. PMID: 1993577.
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    78. Handelman GJ, van Kuijk FJ, Chatterjee A, Krinsky NI. Characterization of products formed during the autoxidation of beta-carotene. Free Radic Biol Med. 1991; 10(6):427-37. PMID: 1894165.
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    79. Krinsky NI, Russett MD, Handelman GJ, Snodderly DM. Structural and geometrical isomers of carotenoids in human plasma. J Nutr. 1990 Dec; 120(12):1654-62. PMID: 2262811.
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    80. Dugast IJ, Papadopoulos P, Zappone E, Jones C, Theriault K, Handelman GJ, Benarous R, Drysdale JW. Identification of two human ferritin H genes on the short arm of chromosome 6. Genomics. 1990 Feb; 6(2):204-11. PMID: 2307464.
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    81. Handelman GJ, Kosted P, Short S, Dratz EA. Determination of selenium in human blood by high-performance liquid chromatography with fluorescence detection. Anal Chem. 1989 Oct 15; 61(20):2244-9. PMID: 2596697.
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    82. Handelman GJ, Dratz EA, Reay CC, van Kuijk JG. Carotenoids in the human macula and whole retina. Invest Ophthalmol Vis Sci. 1988 Jun; 29(6):850-5. PMID: 3372162.
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    83. Handelman GJ, Epstein WL, Machlin LJ, van Kuijk FJ, Dratz EA. Biopsy method for human adipose with vitamin E and lipid measurements. Lipids. 1988 Jun; 23(6):598-604. PMID: 3172989.
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    84. Baker H, Handelman GJ, Short S, Machlin LJ, Bhagavan HN, Dratz EA, Frank O. Comparison of plasma alpha and gamma tocopherol levels following chronic oral administration of either all-rac-alpha-tocopheryl acetate or RRR-alpha-tocopheryl acetate in normal adult male subjects. Am J Clin Nutr. 1986 Mar; 43(3):382-7. PMID: 3953477.
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    85. van Kuijk FJ, Handelman GJ, Dratz EA. Rapid analysis of the major classes of retinoids by step gradient reversed-phase high-performance liquid chromatography using retinal (O-ethyl) oxime derivatives. J Chromatogr. 1985 Nov 27; 348(1):241-51. PMID: 4086639.
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    86. Handelman GJ, Machlin LJ, Fitch K, Weiter JJ, Dratz EA. Oral alpha-tocopherol supplements decrease plasma gamma-tocopherol levels in humans. J Nutr. 1985 Jun; 115(6):807-13. PMID: 3998871.
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    87. van Kuijk FJ, Handelman GJ, Dratz EA. Consecutive action of phospholipase A2 and glutathione peroxidase is required for reduction of phospholipid hydroperoxides and provides a convenient method to determine peroxide values in membranes. J Free Radic Biol Med. 1985; 1(5-6):421-7. PMID: 3837805.
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    88. Katz ML, Parker KR, Handelman GJ, Bramel TL, Dratz EA. Effects of antioxidant nutrient deficiency on the retina and retinal pigment epithelium of albino rats: a light and electron microscopic study. Exp Eye Res. 1982 Mar; 34(3):339-69. PMID: 7067744.
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