Ascorbic Acid

"Ascorbic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.

Descriptor ID	D001205
MeSH Number(s)	D02.241.081.844.107 D02.241.511.902.107 D09.811.100
Concept/Terms	Ascorbic Acid Ascorbic Acid Acid, Ascorbic L-Ascorbic Acid Acid, L-Ascorbic L Ascorbic Acid Vitamin C Hybrin Hybrin Magnorbin Magnorbin Sodium Ascorbate Sodium Ascorbate Ascorbate, Sodium Ascorbic Acid, Monosodium Salt Ferrous Ascorbate Ferrous Ascorbate Ascorbate, Ferrous Magnesium Ascorbate Magnesium Ascorbate Ascorbate, Magnesium Magnesium di-L-Ascorbate Magnesium di L Ascorbate di-L-Ascorbate, Magnesium Magnesium Ascorbicum

Below are MeSH descriptors whose meaning is more general than "Ascorbic Acid".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Carboxylic Acids [D02.241]
Acids, Acyclic [D02.241.081]
Sugar Acids [D02.241.081.844]
Ascorbic Acid [D02.241.081.844.107]
Hydroxy Acids [D02.241.511]
Sugar Acids [D02.241.511.902]
Ascorbic Acid [D02.241.511.902.107]
Carbohydrates [D09]
Sugar Acids [D09.811]
Ascorbic Acid [D09.811.100]

Below are MeSH descriptors whose meaning is related to "Ascorbic Acid".

Below are MeSH descriptors whose meaning is more specific than "Ascorbic Acid".

Ascorbic Acid
Dehydroascorbic Acid

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ascorbic Acid" by people in this website by year, and whether "Ascorbic Acid" was a major or minor topic of these publications.

Bar chart showing 44 publications over 23 distinct years, with a maximum of 5 publications in 2016 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	1	1	2
1998	1	2	3
1999	1	0	1
2002	0	1	1
2003	0	1	1
2006	2	1	3
2007	4	0	4
2009	1	0	1
2010	1	0	1
2011	1	0	1
2012	3	0	3
2014	1	0	1
2015	1	2	3
2016	3	2	5
2017	0	1	1
2018	1	0	1
2019	1	1	2
2020	3	2	5
2021	1	0	1
2022	1	0	1
2024	0	1	1
2025	1	0	1

Below are the most recent publications written about "Ascorbic Acid" by people in Profiles.

Wang Y, Zhou L, Lin S, Zhang J, McClements DJ, Peng S, Liu W. Improving C-phycocyanin photostability by forming complexes with organic acids: l-ascorbic acid, ferulic acid and cinnamic acid. Food Chem. 2025 Oct 30; 490:145012.

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Chung C, Baier S, McClements DJ, Decker EA. Stabilization of myoglobin from different species (produced by cellular agriculture) using food-grade natural and synthetic antioxidants. Food Res Int. 2024 Feb; 178:113965.

View in: PubMed
Coutts CW, Baldwin AM, Jebeli M, Jolin GE, Mungai RW, Billiar KL. The Role of Apoptosis and Oxidative Stress in a Cell Spheroid Model of Calcific Aortic Valve Disease. Cells. 2023 12 25; 13(1).

View in: PubMed
Lee B, An HJ, Kim DH, Lee MK, Jeong HH, Chung KW, Go Y, Seo AY, Kim IY, Seong JK, Yu BP, Lee J, Im E, Lee IK, Lee MS, Yamada KI, Chung HY. SMP30-mediated synthesis of vitamin C activates the liver PPARa/FGF21 axis to regulate thermogenesis in mice. Exp Mol Med. 2022 11; 54(11):2036-2046.

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Mangano KM, Noel SE, Dawson-Hughes B, Tucker KL. Sufficient Plasma Vitamin C Is Related to Greater Bone Mineral Density among Postmenopausal Women from the Boston Puerto Rican Health Study. J Nutr. 2021 12 03; 151(12):3764-3772.

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Siddiqi M, Evans T, Guiab K, Capron G, Roberts A, Messer T, Bokhari F. Vitamin C in the Management of Burn Patients: A Systematic Review of the Risks and Benefits. Am Surg. 2022 04; 88(4):752-757.

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Ishii N, Homma T, Takeda Y, Aung NY, Yamada KI, Miyata S, Asao H, Yamakawa M, Fujii J. Developmental retardation in neonates of aldehyde reductase (AKR1A)-deficient mice is associated with low ascorbic acid and high corticosterone levels. J Nutr Biochem. 2021 05; 91:108604.

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Vail EA, Wunsch H, Pinto R, Bosch NA, Walkey AJ, Lindenauer PK, Gershengorn HB. Use of Hydrocortisone, Ascorbic Acid, and Thiamine in Adults with Septic Shock. Am J Respir Crit Care Med. 2020 12 01; 202(11):1531-1539.

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Homma T, Takeda Y, Nakano T, Akatsuka S, Kinoshita D, Kurahashi T, Saitoh S, Yamada KI, Miyata S, Asao H, Goto K, Watanabe T, Watanabe M, Toyokuni S, Fujii J. Defective biosynthesis of ascorbic acid in Sod1-deficient mice results in lethal damage to lung tissue. Free Radic Biol Med. 2021 01; 162:255-265.

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Kennedy SS, Perilloux A, Pereira RC, Handelman G, Wesseling-Perry K, Salusky IB. Vitamin C overload may contribute to systemic oxalosis in children receiving dialysis. Pediatr Nephrol. 2021 02; 36(2):435-441.

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