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Gerald Downes B.S., Ph.D.

TitleAssociate Professor
InstitutionUniversity of Massachusetts Amherst
DepartmentCollege of Natural Sciences
Address427 Morrill Science Center II
Amherst, MA 01003
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kulick D, Moon E, Riffe RM, Teicher G, Van Deursen S, Berson A, He W, Aaron G, Downes GB, Devoto S, O'Neil A. Amyotrophic Lateral Sclerosis-Associated Persistent Organic Pollutant cis-Chlordane Causes GABAA-Independent Toxicity to Motor Neurons, Providing Evidence toward an Environmental Component of Sporadic Amyotrophic Lateral Sclerosis. ACS Chem Neurosci. 2022 12 21; 13(24):3567-3577. PMID: 36511510.
      Citations: 2     Fields:    
    2. Barnaby W, Dorman Barclay HE, Nagarkar A, Perkins M, Teicher G, Trapani JG, Downes GB. GABAA a subunit control of hyperactive behavior in developing zebrafish. Genetics. 2022 04 04; 220(4). PMID: 35106556.
      Citations: 1     Fields:    Translation:AnimalsCells
    3. Sant KE, Annunziato K, Conlin S, Teicher G, Chen P, Venezia O, Downes GB, Park Y, Timme-Laragy AR. Developmental exposures to perfluorooctanesulfonic acid (PFOS) impact embryonic nutrition, pancreatic morphology, and adiposity in the zebrafish, Danio rerio. Environ Pollut. 2021 Apr 15; 275:116644. PMID: 33581636.
      Citations: 9     Fields:    Translation:Animals
    4. Yildiz O, Downes GB, Sagerstr?m CG. Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain. Neural Dev. 2019 02 27; 14(1):5. PMID: 30813944.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    5. Monesson-Olson B, McClain JJ, Case AE, Dorman HE, Turkewitz DR, Steiner AB, Downes GB. Expression of the eight GABAA receptor a subunits in the developing zebrafish central nervous system. PLoS One. 2018; 13(4):e0196083. PMID: 29702678.
      Citations: 17     Fields:    Translation:Animals
    6. Mott M, Luna VM, Park JY, Downes GB, Epley K, Ono F. Expressing acetylcholine receptors after innervation suppresses spontaneous vesicle release and causes muscle fatigue. Sci Rep. 2017 05 10; 7(1):1674. PMID: 28490756.
      Citations: 3     Fields:    Translation:AnimalsCells
    7. Johnson K, Barragan J, Bashiruddin S, Smith CJ, Tyrrell C, Parsons MJ, Doris R, Kucenas S, Downes GB, Velez CM, Schneider C, Sakai C, Pathak N, Anderson K, Stein R, Devoto SH, Mumm JS, Barresi MJ. Gfap-positive radial glial cells are an essential progenitor population for later-born neurons and glia in the zebrafish spinal cord. Glia. 2016 07; 64(7):1170-89. PMID: 27100776.
      Citations: 30     Fields:    Translation:AnimalsCells
    8. Zannino DA, Downes GB, Sagerstr?m CG. prdm12b specifies the p1 progenitor domain and reveals a role for V1 interneurons in swim movements. Dev Biol. 2014 Jun 15; 390(2):247-60. PMID: 24631215.
      Citations: 11     Fields:    Translation:AnimalsCells
    9. de Soysa TY, Ulrich A, Friedrich T, Pite D, Compton SL, Ok D, Bernardos RL, Downes GB, Hsieh S, Stein R, Lagdameo MC, Halvorsen K, Kesich LR, Barresi MJ. Macondo crude oil from the Deepwater Horizon oil spill disrupts specific developmental processes during zebrafish embryogenesis. BMC Biol. 2012 May 04; 10:40. PMID: 22559716.
      Citations: 11     Fields:    Translation:AnimalsPHPublic Health
    10. Khan TM, Benaich N, Malone CF, Bernardos RL, Russell AR, Downes GB, Barresi MJ, Hutson LD. Vincristine and bortezomib cause axon outgrowth and behavioral defects in larval zebrafish. J Peripher Nerv Syst. 2012 Mar; 17(1):76-89. PMID: 22462669.
      Citations: 7     Fields:    Translation:AnimalsCells
    11. McKeown KA, Moreno R, Hall VL, Ribera AB, Downes GB. Disruption of Eaat2b, a glutamate transporter, results in abnormal motor behaviors in developing zebrafish. Dev Biol. 2012 Feb 15; 362(2):162-71. PMID: 22094018.
      Citations: 20     Fields:    Translation:AnimalsCells
    12. Friedrich T, Lambert AM, Masino MA, Downes GB. Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease. Dis Model Mech. 2012 Mar; 5(2):248-58. PMID: 22046030.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    13. Olson BD, Sgourdou P, Downes GB. Analysis of a zebrafish behavioral mutant reveals a dominant mutation in atp2a1/SERCA1. Genesis. 2010 Jun; 48(6):354-61. PMID: 20533403.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    14. McKeown KA, Downes GB, Hutson LD. Modular laboratory exercises to analyze the development of zebrafish motor behavior. Zebrafish. 2009 Jun; 6(2):179-85. PMID: 19537944.
      Citations: 13     Fields:    Translation:Animals
    15. Downes GB, Granato M. Supraspinal input is dispensable to generate glycine-mediated locomotive behaviors in the zebrafish embryo. J Neurobiol. 2006 Apr; 66(5):437-51. PMID: 16470684.
      Citations: 38     Fields:    Translation:AnimalsCells
    16. Hirata H, Saint-Amant L, Downes GB, Cui WW, Zhou W, Granato M, Kuwada JY. Zebrafish bandoneon mutants display behavioral defects due to a mutation in the glycine receptor beta-subunit. Proc Natl Acad Sci U S A. 2005 Jun 07; 102(23):8345-50. PMID: 15928085.
      Citations: 50     Fields:    Translation:AnimalsCells
    17. Downes GB, Granato M. Acetylcholinesterase function is dispensable for sensory neurite growth but is critical for neuromuscular synapse stability. Dev Biol. 2004 Jun 01; 270(1):232-45. PMID: 15136152.
      Citations: 39     Fields:    Translation:AnimalsCells
    18. Downes GB, Waterbury JA, Granato M. Rapid in vivo labeling of identified zebrafish neurons. Genesis. 2002 Nov; 34(3):196-202. PMID: 12395384.
      Citations: 13     Fields:    Translation:AnimalsCells
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