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Giacomo P. Basadonna MD, PhD

TitleProfessor Emeritus
InstitutionUMass Chan Medical School
DepartmentSurgery
AddressUMass Chan Medical School
377 Plantation Street
Worcester MA 01605
Phone508-334-2022
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentSurgery
    DivisionOrgan Transplantation


    Collapse Biography 
    Collapse education and training
    University of Milan, Milano, MI, ItalyMD
    University of Milan, Milano, MI, ItalyPHDSurgery

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Canady J, Murthy SRK, Zhuang T, Gitelis S, Nissan A, Ly L, Jones OZ, Cheng X, Adileh M, Blank AT, Colman MW, Millikan K, O'Donoghue C, Stenson KM, Ohara K, Schtrechman G, Keidar M, Basadonna G. The First Cold Atmospheric Plasma Phase I Clinical Trial for the Treatment of Advanced Solid Tumors: A Novel Treatment Arm for Cancer. Cancers (Basel). 2023 Jul 20; 15(14). PMID: 37509349.
      Citations:    
    2. Ly L, Cheng X, Murthy SRK, Jones OZ, Zhuang T, Gitelis S, Blank AT, Nissan A, Adileh M, Colman M, Keidar M, Basadonna G, Canady J. Canady Cold Helios Plasma Reduces Soft Tissue Sarcoma Viability by Inhibiting Proliferation, Disrupting Cell Cycle, and Inducing Apoptosis: A Preliminary Report. Molecules. 2022 Jun 29; 27(13). PMID: 35807413.
      Citations: 3     Fields:    Translation:Humans
    3. Murthy SRK, Cheng X, Zhuang T, Ly L, Jones O, Basadonna G, Keidar M, Canady J. BCL2A1 regulates Canady Helios Cold Plasma-induced cell death in triple-negative breast cancer. Sci Rep. 2022 03 08; 12(1):4038. PMID: 35260587.
      Citations: 5     Fields:    Translation:Humans
    4. Cheng X, Murthy SRK, Zhuang T, Ly L, Jones O, Basadonna G, Keidar M, Kanaan Y, Canady J. Canady Helios Cold Plasma Induces Breast Cancer Cell Death by Oxidation of Histone mRNA. Int J Mol Sci. 2021 Sep 03; 22(17). PMID: 34502492.
      Citations: 7     Fields:    Translation:HumansCells
    5. Jones O, Cheng X, Murthy SRK, Ly L, Zhuang T, Basadonna G, Keidar M, Canady J. The synergistic effect of Canady Helios cold atmospheric plasma and a FOLFIRINOX regimen for the treatment of cholangiocarcinoma in vitro. Sci Rep. 2021 04 26; 11(1):8967. PMID: 33903679.
      Citations: 5     Fields:    Translation:HumansCells
    6. Selby NM, Korrodi-Greg?rio L, Casula A, Kolhe NV, Arbon?s DR, Bukieda KD, Sahu D, Rao C, Basadonna G. Randomized Controlled Trial Evidence of Cost-Effectiveness of a Multifaceted AKI Intervention Approach. Kidney Int Rep. 2021 Mar; 6(3):636-644. PMID: 33732978.
      Citations:    
    7. Fazzalari A, Basadonna G, Kucukural A, Tanriverdi K, Koupenova M, Pozzi N, Kakuturu J, Friedrich AU, Korstanje R, Fowler N, Belant JL, Beyer DE, Brooks MB, Dickson EW, Blackwood M, Mueller C, Palesty JA, Freedman JE, Cahan MA. A Translational Model for Venous Thromboembolism: MicroRNA Expression in Hibernating Black Bears. J Surg Res. 2021 01; 257:203-212. PMID: 32858321.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    8. McQuilling JP, Sanders M, Poland L, Sanders M, Basadonna G, Waldrop NE, Mowry KC. Dehydrated Amnion/Chorion Improves Achilles Tendon Repair in a Diabetic Animal Model. Wounds. 2019 01; 31(1):19-25. PMID: 30372415.
      Citations: 10     Fields:    Translation:Animals
    9. Friedrich AU, Kakuturu J, Schnorr PJ, Beyer DE, Palesty JA, Dickson EW, Basadonna G, Cahan MA. Comparative coagulation studies in hibernating and summer-active black bears (Ursus americanus). Thromb Res. 2017 Oct; 158:16-18. PMID: 28783512.
      Citations: 4     Fields:    Translation:Animals
    10. Basadonna G. QuikClot combat gauze for hemorrhage control. Prehosp Disaster Med. 2012 Apr; 27(2):217. PMID: 22588520.
      Citations: 4     Fields:    Translation:Humans
    11. Stegall MD, Dean PG, Sung R, Guidinger MK, McBride MA, Sommers C, Basadonna G, Stock PG, Leichtman AB. The rationale for the new deceased donor pancreas allocation schema. Transplantation. 2007 May 15; 83(9):1156-61. PMID: 17496529.
      Citations: 13     Fields:    Translation:Humans
    12. Magee JC, Barr ML, Basadonna GP, Johnson MR, Mahadevan S, McBride MA, Schaubel DE, Leichtman AB. Repeat organ transplantation in the United States, 1996-2005. Am J Transplant. 2007; 7(5 Pt 2):1424-33. PMID: 17428290.
      Citations: 47     Fields:    Translation:Humans
    13. Whiting JF, Delmonico F, Morrissey P, Basadonna G, Johnson S, Lewis WD, Rohrer R, O'Connor K, Bradley J, Lovewell TD, Lipkowitz G. Clinical results of an organ procurement organization effort to increase utilization of donors after cardiac death. Transplantation. 2006 May 27; 81(10):1368-71. PMID: 16732170.
      Citations: 8     Fields:    Translation:Humans
    14. Salvalaggio PR, Camirand G, Ariyan CE, Deng S, Rogozinski L, Basadonna GP, Rothstein DM. Antigen exposure during enhanced CTLA-4 expression promotes allograft tolerance in vivo. J Immunol. 2006 Feb 15; 176(4):2292-8. PMID: 16455985.
      Citations: 9     Fields:    Translation:Animals
    15. Dohi T, Salz W, Costa M, Ariyan C, Basadonna GP, Altieri DC. Inhibition of apoptosis by survivin improves transplantation of pancreatic islets for treatment of diabetes in mice. EMBO Rep. 2006 Apr; 7(4):438-43. PMID: 16470228.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    16. Bradley SP, Rastellini C, da Costa MA, Kowalik TF, Bloomenthal AB, Brown M, Cicalese L, Basadonna GP, Uknis ME. Gene silencing in the endocrine pancreas mediated by short-interfering RNA. Pancreas. 2005 Nov; 31(4):373-9. PMID: 16258373.
      Citations: 16     Fields:    Translation:Animals
    17. Sho M, Kishimoto K, Harada H, Livak M, Sanchez-Fueyo A, Yamada A, Zheng XX, Strom TB, Basadonna GP, Sayegh MH, Rothstein DM. Requirements for induction and maintenance of peripheral tolerance in stringent allograft models. Proc Natl Acad Sci U S A. 2005 Sep 13; 102(37):13230-5. PMID: 16150717.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    18. Bradley SP, Kowalik TF, Rastellini C, da Costa MA, Bloomenthal AB, Cicalese L, Basadonna GP, Uknis ME. Successful incorporation of short-interfering RNA into islet cells by in situ perfusion. Transplant Proc. 2005 Jan-Feb; 37(1):233-6. PMID: 15808605.
      Citations: 9     Fields:    Translation:AnimalsCells
    19. Delmonico FL, Morrissey PE, Lipkowitz GS, Stoff JS, Himmelfarb J, Harmon W, Pavlakis M, Mah H, Goguen J, Luskin R, Milford E, Basadonna G, Chobanian M, Bouthot B, Lorber M, Rohrer RJ. Donor kidney exchanges. Am J Transplant. 2004 Oct; 4(10):1628-34. PMID: 15367217.
      Citations: 15     Fields:    Translation:Humans
    20. Gaston RS, Basadonna G, Cosio FG, Davis CL, Kasiske BL, Larsen J, Leichtman AB, Delmonico FL. Transplantation in the diabetic patient with advanced chronic kidney disease: a task force report. Am J Kidney Dis. 2004 Sep; 44(3):529-42. PMID: 15332226.
      Citations: 12     Fields:    Translation:Humans
    21. Bassetti M, Salvalaggio PR, Topal J, Lorber MI, Friedman AL, Andriole VT, Basadonna GP. Incidence, timing and site of infections among pancreas transplant recipients. J Hosp Infect. 2004 Mar; 56(3):184-90. PMID: 15003665.
      Citations: 5     Fields:    Translation:Humans
    22. Friedman AL, Goker O, Kalish MA, Basadonna GP, Kliger AS, Bia MJ, Lorber MI. Renal transplant recipients over aged 60 have diminished immune activity and a low risk of rejection. Int Urol Nephrol. 2004; 36(3):451-6. PMID: 15783123.
      Citations: 4     Fields:    Translation:Humans
    23. Salvalaggio PR, Bassetti M, Lorber MI, Micheletto GC, Friedman AL, Andriole VT, Basadonna GP. Aspergillus vertebral osteomyelitis after simultaneous kidney-pancreas transplantation. Transpl Infect Dis. 2003 Dec; 5(4):187-90. PMID: 14987203.
      Citations: 6     Fields:    Translation:Humans
    24. Ariyan C, Salvalaggio P, Fecteau S, Deng S, Rogozinski L, Mandelbrot D, Sharpe A, Sayegh MH, Basadonna GP, Rothstein DM. Cutting edge: transplantation tolerance through enhanced CTLA-4 expression. J Immunol. 2003 Dec 01; 171(11):5673-7. PMID: 14634073.
      Citations: 29     Fields:    Translation:AnimalsCells
    25. Molano RD, Pileggi A, Berney T, Poggioli R, Zahr E, Oliver R, Ricordi C, Rothstein DM, Basadonna GP, Inverardi L. Prolonged islet allograft survival in diabetic NOD mice by targeting CD45RB and CD154. Diabetes. 2003 Apr; 52(4):957-64. PMID: 12663467.
      Citations: 15     Fields:    Translation:AnimalsCells
    26. Salvalaggio PR, Deng S, Ariyan CE, Millet I, Zawalich WS, Basadonna GP, Rothstein DM. Islet filtration: a simple and rapid new purification procedure that avoids ficoll and improves islet mass and function. Transplantation. 2002 Sep 27; 74(6):877-9. PMID: 12364870.
      Citations: 55     Fields:    Translation:AnimalsCells
    27. Cruz DN, Brickel HM, Wysolmerski JJ, Gundberg CG, Simpson CA, Kliger AS, Lorber MI, Basadonna GP, Friedman AL, Insogna KL, Bia MJ. Treatment of osteoporosis and osteopenia in long-term renal transplant patients with alendronate. Am J Transplant. 2002 Jan; 2(1):62-7. PMID: 12095058.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    28. Lorber MI, Basadonna GP, Friedman AL, Lorber KM, Bia MJ, Formica R, Smith JD. The evolving role of tor inhibitors for individualizing posttransplant immunosuppression. Transplant Proc. 2001 Nov-Dec; 33(7-8):3075-7. PMID: 11750322.
      Citations: 2     Fields:    Translation:HumansCells
    29. Cruz DN, Wysolmerski JJ, Brickel HM, Gundberg CG, Simpson CA, Mitnick MA, Kliger AS, Lorber MI, Basadonna GP, Friedman AL, Insogna KL, Bia MJ. Parameters of high bone-turnover predict bone loss in renal transplant patients: a longitudinal study. Transplantation. 2001 Jul 15; 72(1):83-8. PMID: 11468539.
      Citations: 12     Fields:    Translation:Humans
    30. Bassetti M, Topal J, Di Biagio A, Salvalaggio P, Basadonna GP, Bassetti D. The organization of infection control in Italy. J Hosp Infect. 2001 Jun; 48(2):83-5. PMID: 11428872.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    31. Molano RD, Berney T, Pileggi A, Ricordi C, Burkly L, Rothstein D, Basadonna G, Inverardi L. Prolonged survival of allogeneic islet grafts in NOD mice treated with a combination of anti-CD45RB and anti-CD154 antibodies. Transplant Proc. 2001 Feb-Mar; 33(1-2):248-9. PMID: 11266802.
      Citations: 3     Fields:    Translation:Animals
    32. Fecteau S, Basadonna GP, Freitas A, Ariyan C, Sayegh MH, Rothstein DM. CTLA-4 up-regulation plays a role in tolerance mediated by CD45. Nat Immunol. 2001 Jan; 2(1):58-63. PMID: 11135579.
      Citations: 27     Fields:    Translation:AnimalsCells
    33. Rothstein DM, Livak MF, Kishimoto K, Ariyan C, Qian HY, Fecteau S, Sho M, Deng S, Zheng XX, Sayegh MH, Basadonna GP. Targeting signal 1 through CD45RB synergizes with CD40 ligand blockade and promotes long term engraftment and tolerance in stringent transplant models. J Immunol. 2001 Jan 01; 166(1):322-9. PMID: 11123308.
      Citations: 18     Fields:    Translation:AnimalsCells
    34. Cayco AV, Wysolmerski J, Simpson C, Mitnick MA, Gundberg C, Kliger A, Lorber M, Silver D, Basadonna G, Friedman A, Insogna K, Cruz D, Bia M. Posttransplant bone disease: evidence for a high bone resorption state. Transplantation. 2000 Dec 27; 70(12):1722-8. PMID: 11152104.
      Citations: 14     Fields:    Translation:Humans
    35. Gaber AO, First MR, Tesi RJ, Gaston RS, Mendez R, Mulloy LL, Light JA, Gaber LW, Squiers E, Taylor RJ, Neylan JF, Steiner RW, Knechtle S, Norman DJ, Shihab F, Basadonna G, Brennan DC, Hodge EE, Kahan BD, Kahan L, Steinberg S, Woodle ES, Chan L, Ham JM, Schroeder TJ, et al. Results of the double-blind, randomized, multicenter, phase III clinical trial of Thymoglobulin versus Atgam in the treatment of acute graft rejection episodes after renal transplantation. Transplantation. 1998 Jul 15; 66(1):29-37. PMID: 9679818.
      Citations: 46     Fields:    Translation:HumansAnimalsCTClinical Trials
    36. Basadonna GP, Auersvald L, Khuong CQ, Zheng XX, Kashio N, Zekzer D, Minozzo M, Qian H, Visser L, Diepstra A, Lazarovits AI, Poppema S, Strom TB, Rothstein DM. Antibody-mediated targeting of CD45 isoforms: a novel immunotherapeutic strategy. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3821-6. PMID: 9520451.
      Citations: 16     Fields:    Translation:Animals
    37. Darenkov IA, Marcarelli MA, Basadonna GP, Friedman AL, Lorber KM, Howe JG, Crouch J, Bia MJ, Kliger AS, Lorber MI. Reduced incidence of Epstein-Barr virus-associated posttransplant lymphoproliferative disorder using preemptive antiviral therapy. Transplantation. 1997 Sep 27; 64(6):848-52. PMID: 9326409.
      Citations: 35     Fields:    Translation:HumansCells
    38. Auersvald LA, Rothstein DM, Oliveira SC, Khuong CQ, Onodera H, Lazarovits AI, Basadonna GP. Indefinite islet allograft survival in mice after a short course of treatment with anti-CD45 monoclonal antibodies. Transplantation. 1997 May 15; 63(9):1355-8. PMID: 9158033.
      Citations: 5     Fields:    Translation:Animals
    39. Auersvald LA, Rothstein DM, Oliveira SC, Khuong CQ, Basadonna GP. Anti-CD45RB treatment prolongs islet allograft survival in mice. Transplant Proc. 1997 Feb-Mar; 29(1-2):771. PMID: 9123520.
      Citations: 4     Fields:    Translation:Animals
    40. Lee LS, Auersvald LA, Claus EB, Bia MJ, Friedman AL, Lorber MI, Basadonna GP. Body size mismatch between donor and recipient and the development of chronic rejection in renal transplantation. Transplant Proc. 1997 Feb-Mar; 29(1-2):111. PMID: 9122918.
      Citations: 1     Fields:    Translation:Humans
    41. Basadonna GP, Auersvald LA, Oliveira SC, Friedman AL, Lorber MI. Pancreas after kidney transplantation: HLA mismatch does not preclude success. Transplant Proc. 1997 Feb-Mar; 29(1-2):667. PMID: 9123470.
      Citations: 1     Fields:    Translation:Humans
    42. Friedman AL, Goker O, Dennis MJ, Basadonna GP, Wiklund RA, Kliger A, Bia MJ, Lorber MI. Must living renal donors be hospitalized overnight prior to surgery? Clin Transplant. 1996 Oct; 10(5):444-6. PMID: 8930459.
      Citations:    Fields:    Translation:Humans
    43. Basadonna G, Choi-Lee H, Chao CT, Swanson C, Morgan M, Wong A, Curry D, Perez R. Effect of warm ischemia on insulin secretion in non-heart-beating donors. Transplant Proc. 1995 Oct; 27(5):2793-4. PMID: 7482917.
      Citations: 1     Fields:    Translation:HumansAnimals
    44. Basadonna G, Feria A, Perez R, Klein H, Sturges M, Colquhoun S. Incidence of infection and acute rejection after cytomegalovirus immune globulin prophylaxis in renal transplantation. Transplant Proc. 1994 Oct; 26(5 Suppl 1):52-3. PMID: 7940976.
      Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
    45. Basadonna GP, Matas AJ, Gillingham KJ, Payne WD, Dunn DL, Sutherland DE, Gores PF, Gruessner RW, Najarian JS. Early versus late acute renal allograft rejection: impact on chronic rejection. Transplantation. 1993 May; 55(5):993-5. PMID: 8497913.
      Citations: 31     Fields:    Translation:Humans
    46. Basadonna GP, Arrazola L, Matas AJ, Gruessner R, Schmidt W, Sutherland DE. Morbidity, mortality, and long-term allograft function in kidney transplantation alone and simultaneous pancreas-kidney in diabetic patients. Transplant Proc. 1993 Feb; 25(1 Pt 2):1321-2. PMID: 8442128.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    47. Basadonna G, Matas AJ, Najarian JS. Kidney transplantation in diabetic patients: the University of Minnesota experience. Kidney Int Suppl. 1992 Oct; 38:S193-6. PMID: 1405374.
      Citations: 2     Fields:    Translation:Humans
    48. Kakizaki K, Didlake R, Basadonna G, Kahan BD, Merrell RC. Donor-specific antigen and cyclosporine in rat islet allografts. J Surg Res. 1987 May; 42(5):494-7. PMID: 3108582.
      Citations:    Fields:    Translation:Animals
    49. Kakizaki K, Basadonna G, Merrell RC. Allotransplantation of islet endocrine aggregates. Diabetes. 1987 Mar; 36(3):315-9. PMID: 3100371.
      Citations: 2     Fields:    Translation:Animals
    50. Basadonna G, Kakizaki K, Merrell RC. Effect of cyclosporine on established islet autografts. J Surg Res. 1986 May; 40(5):450-4. PMID: 3090372.
      Citations: 3     Fields:    Translation:Animals
    51. Merrell RC, Maeda M, Basadonna G, Marincola F, Cobb L. Suppression, stress, and accommodation of transplanted islets of Langerhans. Diabetes. 1985 Jul; 34(7):667-70. PMID: 3924694.
      Citations: 4     Fields:    Translation:Animals
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