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Ediz F Cosar MD

TitleAssociate Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentPathology
AddressUMass Memorial Medical Center
119 Belmont Street
Worcester MA 01605
Phone508-793-6184
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentPathology
    DivisionAnatomic Pathology


    Collapse Biography 
    Collapse education and training
    Cukurova University School of Medicine, Adana, , TurkeyMDMedicine

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    Academic Background

    M.D. Degree, Çukurova University School of Medicine, Adana, TURKEY 1988

    Resident, Anatomic Pathology, Cukurova University School of Medicine,Department of Pathology, Adana, TURKEY, 1989-1995

    Resident, Anatomic and Clinical Pathology, Department of Pathology, Illinois Masonic Medical Center, Chicago, Illinois 1998 – 1999

    Resident, Anatomic and Clinical Pathology, Department of Pathology, Loyola University Medical Center, Maywood, Illinois 1999 – 2002

    Fellow, Molecular Genetic Pathology, Department of Pathology, Loyola University Medical Center, Maywood, Illinois 2002 – 2003

    Fellow, Cytopathology, Department of Pathology, University of Massachusetts Memorial Medical Center,Worcester, Massachusetts 2003 – 2004

    Subspecialty Areas:Cytopathology, Molecular Diagnostics, Genitourinary PathologyDr. Cosar's picture

    Research Interests: My main research interest is biomarkers in the diagnosis and prognosis of neoplastic diseases. In our Diagnostic Molecular Oncology laboratory, using an automated imaging system we have implemented an integrated cytopathology and fluorescence in situ hybridization approach in the diagnosis of urothelial carcinomas. This system also allows us to explore potential markers that might be helpful in diagnosis and prognosis of urothelial and other organ system neoplasms.




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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Cornejo KM, Cosar EF, Paner GP, Yang P, Tomaszewicz K, Meng X, Mehta V, Sirintrapun SJ, Barkan GA, Hutchinson L. Mutational Profile Using Next-Generation Sequencing May Aid in the Diagnosis and Treatment of Urachal Adenocarcinoma. Int J Surg Pathol. 2019 Sep 08; 1066896919872535. PMID: 31496327.
      View in: PubMed
    2. Javvaji C, Bledsoe JR, Hutchinson L, Cosar EF, McIntosh LJ, Bathini VG. Metastatic Signet Ring Cell Carcinoma of the Ampulla of Vater with an Unusually Prolonged Survival. J Gastrointest Cancer. 2019 Aug 27. PMID: 31456115.
      View in: PubMed
    3. Sakhdari A, Moghaddam PA, Ok CY, Walter O, Tomaszewicz K, Caporelli ML, Meng X, LaFemina J, Whalen G, Belkin E, Zivny J, Wassef W, Woda BA, Hutchinson LM, Cosar EF. Somatic molecular analysis augments cytologic evaluation of pancreatic cyst fluids as a diagnostic tool. Oncotarget. 2019 Jun 18; 10(40):4026-4037. PMID: 31258847.
      View in: PubMed
    4. Bai S, Hutchinson LM, Meng X, Bai H, Cosar EF, Khan A, Cornejo K. Dedifferentiated Carcinoma of the Endometrium Associated With Low-Grade Müllerian Adenosarcoma: A Clinicopathologic Case Report Including the Immunohistochemical and Molecular Profile. Int J Gynecol Pathol. 2019 Mar 22. PMID: 30908285.
      View in: PubMed
    5. Zhu X, Salhab M, Tomaszewicz K, Meng X, Mathew C, Bathini V, Switzer B, Walter O, Cosar EF, Wang X, Lambert LA, Hutchinson LM. Heterogeneous mutational profile and prognosis conferred by TP53 mutations in Appendiceal mucinous neoplasms. Hum Pathol. 2018 Nov 17. PMID: 30458197.
      View in: PubMed
    6. Liu Q, Cornejo KM, Cheng L, Hutchinson L, Wang M, Zhang S, Tomaszewicz K, Cosar EF, Woda BA, Jiang Z. Next-Generation Sequencing to Detect Deletion of RB1 and ERBB4 Genes in Chromophobe Renal Cell Carcinoma: A Potential Role in Distinguishing Chromophobe Renal Cell Carcinoma from Renal Oncocytoma. Am J Pathol. 2018 Apr; 188(4):846-852. PMID: 29353061.
      View in: PubMed
    7. Sakhdari A, Hutchinson L, Vaskas N, Scott M, Cosar EF, Al-Turkmani R. Routine Analysis of Lipase in Cyst Fluid Is Unnecessary and Does Not Help Discriminate Between Nonneoplastic and Neoplastic Cystic Pancreatic Lesions. Pancreas. 2017 Mar; 46(3):e25-e27. PMID: 28187114.
      View in: PubMed
    8. Cornejo KM, Cosar EF, O'Donnell P. Cutaneous Intralymphatic Histiocytosis Associated With Lung Adenocarcinoma. Am J Dermatopathol. 2016 Jul; 38(7):568-70. PMID: 27322793.
      View in: PubMed
    9. Zhou AG, Liu Y, Cyr MS, Garver J, Woda BA, Cosar EF, Hutchinson LM. Role of Tetrasomy for the Diagnosis of Urothelial Carcinoma Using UroVysion Fluorescent In Situ Hybridization. Arch Pathol Lab Med. 2016 Jun; 140(6):552-9. PMID: 27232347.
      View in: PubMed
    10. Kamionek M, Ahmadi Moghaddam P, Sakhdari A, Kovach AE, Welch M, Meng X, Dresser K, Tomaszewicz K, Cosar EF, Mark EJ, Fraire AE, Hutchinson L. Mutually exclusive extracellular signal-regulated kinase pathway mutations are present in different stages of multi-focal pulmonary Langerhans cell histiocytosis supporting clonal nature of the disease. Histopathology. 2016 Sep; 69(3):499-509. PMID: 26915300.
      View in: PubMed
    11. Moghaddam PA, Virk R, Sakhdari A, Prasad ML, Cosar EF, Khan A. Five Top Stories in Thyroid Pathology. Arch Pathol Lab Med. 2016 Feb; 140(2):158-70. PMID: 26910221.
      View in: PubMed
    12. Cornejo KM, Deng A, Wu H, Cosar EF, Khan A, St Cyr M, Tomaszewicz K, Dresser K, O'Donnell P, Hutchinson L. The utility of MYC and FLT4 in the diagnosis and treatment of postradiation atypical vascular lesion and angiosarcoma of the breast. Hum Pathol. 2015 Jun; 46(6):868-75. PMID: 25864386.
      View in: PubMed
    13. Rosenblum F, Hutchinson LM, Garver J, Woda B, Cosar E, Kurian EM. Cytology specimens offer an effective alternative to formalin-fixed tissue as demonstrated by novel automated detection for ALK break-apart FISH testing and immunohistochemistry in lung adenocarcinoma. Cancer Cytopathol. 2014 Nov; 122(11):810-21. PMID: 25099128.
      View in: PubMed
    14. Cornejo KM, Hutchinson L, Deng A, Tomaszewicz K, Welch M, Lyle S, Dresser K, Cosar EF. BRAF/KRAS gene sequencing of sebaceous neoplasms after mismatch repair protein analysis. Hum Pathol. 2014 Jun; 45(6):1213-20. PMID: 24767862.
      View in: PubMed
    15. Cornejo KM, Kandil D, Khan A, Cosar EF. Theranostic and molecular classification of breast cancer. Arch Pathol Lab Med. 2014 Jan; 138(1):44-56. PMID: 24377811.
      View in: PubMed
    16. Yang X, Kandil D, Cosar EF, Khan A. Fibroepithelial tumors of the breast: pathologic and immunohistochemical features and molecular mechanisms. Arch Pathol Lab Med. 2014 Jan; 138(1):25-36. PMID: 24377809.
      View in: PubMed
    17. Zhou AG, Hutchinson LM, Cosar EF. Urine Cytopathology and Ancillary Methods. Surg Pathol Clin. 2014 Mar; 7(1):77-88. PMID: 26839270.
      View in: PubMed
    18. Cornejo KM, Hutchinson L, Cosar EF, Smith T, Tomaszewicz K, Dresser K, Deng A. Is it a primary or metastatic melanocytic neoplasm of the central nervous system?: A molecular based approach. Pathol Int. 2013 Nov; 63(11):559-64. PMID: 24274719.
      View in: PubMed
    19. Zhou AG, Owens CL, Cosar EF, Jiang Z. Clinical implications of current developments in genitourinary pathology. Arch Pathol Lab Med. 2013 Jul; 137(7):887-93. PMID: 23808460.
      View in: PubMed
    20. Morgan TK, Hardiman K, Corless CL, White SL, Bonnah R, Van de Vrugt H, Sheppard BC, Grompe M, Cosar EF, Streeter PR. Human pancreatic cancer fusion 2 (HPC2) 1-B3: a novel monoclonal antibody to screen for pancreatic ductal dysplasia. Cancer Cytopathol. 2013 Jan; 121(1):37-46. PMID: 22811080.
      View in: PubMed
    21. Kurian EM, Caporelli ML, Baker S, Woda B, Cosar EF, Hutchinson L. Cervista HR and HPV 16/18 assays vs hybrid capture 2 assay: outcome comparison in women with negative cervical cytology. Am J Clin Pathol. 2011 Nov; 136(5):808-16. PMID: 22031321.
      View in: PubMed
    22. Yantiss RK, Cosar E, Fischer AH. Use of IMP3 in identification of carcinoma in fine needle aspiration biopsies of pancreas. Acta Cytol. 2008 Mar-Apr; 52(2):133-8. PMID: 18499984.
      View in: PubMed
    23. Mercader M, Sengupta S, Bodner BK, Manecke RG, Cosar EF, Moser MT, Ballman KV, Wojcik EM, Kwon ED. Early effects of pharmacological androgen deprivation in human prostate cancer. BJU Int. 2007 Jan; 99(1):60-7. PMID: 17227493.
      View in: PubMed
    24. Reddy D, Salomon C, Demos TC, Cosar E. Mesenteric lymph node cavitation in celiac disease. AJR Am J Roentgenol. 2002 Jan; 178(1):247. PMID: 11756139.
      View in: PubMed
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