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Ediz F Cosar MD

TitleAssociate Professor
InstitutionUMass Chan – Baystate Regional Campus
DepartmentPathology at UMass Chan - Baystate
AddressUMass Memorial Medical Center
119 Belmont Street
Worcester MA 01605
Phone508-793-6184
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentPathology
    DivisionAnatomic Pathology


    Collapse Biography 
    Collapse education and training
    Cukurova University School of Medicine, Adana, , TurkeyMDMedicine

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    Academic Background

    M.D. Degree, Çukurova University School of Medicine, Adana, TURKEY 1988

    Resident, Anatomic Pathology, Cukurova University School of Medicine,Department of Pathology, Adana, TURKEY, 1989-1995

    Resident, Anatomic and Clinical Pathology, Department of Pathology, Illinois Masonic Medical Center, Chicago, Illinois 1998 – 1999

    Resident, Anatomic and Clinical Pathology, Department of Pathology, Loyola University Medical Center, Maywood, Illinois 1999 – 2002

    Fellow, Molecular Genetic Pathology, Department of Pathology, Loyola University Medical Center, Maywood, Illinois 2002 – 2003

    Fellow, Cytopathology, Department of Pathology, University of Massachusetts Memorial Medical Center,Worcester, Massachusetts 2003 – 2004

    Subspecialty Areas:Cytopathology, Molecular Diagnostics, Genitourinary PathologyDr. Cosar's picture

    Research Interests: My main research interest is biomarkers in the diagnosis and prognosis of neoplastic diseases. In our Diagnostic Molecular Oncology laboratory, using an automated imaging system we have implemented an integrated cytopathology and fluorescence in situ hybridization approach in the diagnosis of urothelial carcinomas. This system also allows us to explore potential markers that might be helpful in diagnosis and prognosis of urothelial and other organ system neoplasms.



    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Liao H, Sheridan T, Cosar E, Owens C, Zuo T, Wang X, Akalin A, Kandil D, Dresser K, Fogarty K, Bellve K, Baer C, Fischer A. Deconvolution microscopy: A platform for rapid on-site evaluation of fine needle aspiration specimens that enables recovery of the sample. Cytopathology. 2022 05; 33(3):312-320. PMID: 35102620.
      Citations: 1     Fields:    Translation:Humans
    2. Fahmy OH, Daas FM, Salunkhe V, Petrey JL, Cosar EF, Ramirez J, Akca O. Is Microthrombosis the Main Pathology in Coronavirus Disease 2019 Severity?-A Systematic Review of the Postmortem Pathologic Findings. Crit Care Explor. 2021 May; 3(5):e0427. PMID: 34036278.
      Citations:    
    3. Sun T, Hutchinson L, Tomaszewicz K, Caporelli ML, Meng X, McCauley K, Fischer AH, Cosar EF, Cornejo KM. Diagnostic value of a comprehensive, urothelial carcinoma-specific next-generation sequencing panel in urine cytology and bladder tumor specimens. Cancer Cytopathol. 2021 07; 129(7):537-547. PMID: 33539671.
      Citations: 1     Fields:    Translation:Humans
    4. Makarenko VV, Kandil D, Cosar EF, Hutchinson L, Khan A. Molecular analysis of a rare case of low-grade primary peritoneal serous carcinoma in a male. Rare Tumors. 2020; 12:2036361320979219. PMID: 33354307.
      Citations:    
    5. Zou T, Dave S, Adler RN, Manning MJ, Scott MP, Strock C, Kandil D, Cosar E, Fischer AH. Colposcopic endocervical brushing cytology appears to be more sensitive than histologic endocervical curettage for detecting endocervical adenocarcinoma. J Am Soc Cytopathol. 2021 Mar-Apr; 10(2):135-140. PMID: 33097463.
      Citations: 1     Fields:    Translation:Humans
    6. Bai S, Hutchinson LM, Meng X, Bai H, Cosar EF, Khan A, Cornejo K. Dedifferentiated Carcinoma of the Endometrium Associated With Low-grade Müllerian Adenosarcoma: A Clinicopathologic Case Report Including the Immunohistochemical and Molecular Profile. Int J Gynecol Pathol. 2020 Mar; 39(2):141-145. PMID: 30908285.
      Citations:    Fields:    Translation:Humans
    7. Javvaji C, Bledsoe JR, Hutchinson L, Cosar EF, McIntosh LJ, Bathini VG. Metastatic Signet Ring Cell Carcinoma of the Ampulla of Vater with an Unusually Prolonged Survival. J Gastrointest Cancer. 2020 Mar; 51(1):354-358. PMID: 31456115.
      Citations: 1     Fields:    Translation:Humans
    8. Sun T, Hutchinson L, Zhou AG, Liu Q, Cosar EF, St Cyr M, Ninteau N, Dresser K, Cheng L, Jiang Z, Cornejo KM. The Utility of ERBB4 and RB1 Immunohistochemistry in Distinguishing Chromophobe Renal Cell Carcinoma From Renal Oncocytoma. Int J Surg Pathol. 2020 May; 28(3):259-264. PMID: 31640438.
      Citations:    Fields:    Translation:Humans
    9. Sakhdari A, Moghaddam PA, Pejchal M, Cosar EF, Hutchinson L. Sequential molecular and cytologic analyses provides a complementary approach to the diagnosis of pancreatic cystic lesions: a decade of clinical practice. J Am Soc Cytopathol. 2020 Jan - Feb; 9(1):38-44. PMID: 31711852.
      Citations: 1     Fields:    Translation:Humans
    10. Cornejo KM, Cosar EF, Paner GP, Yang P, Tomaszewicz K, Meng X, Mehta V, Sirintrapun SJ, Barkan GA, Hutchinson L. Mutational Profile Using Next-Generation Sequencing May Aid in the Diagnosis and Treatment of Urachal Adenocarcinoma. Int J Surg Pathol. 2020 Feb; 28(1):51-59. PMID: 31496327.
      Citations: 1     Fields:    Translation:Humans
    11. Sakhdari A, Moghaddam PA, Ok CY, Walter O, Tomaszewicz K, Caporelli ML, Meng X, LaFemina J, Whalen G, Belkin E, Zivny J, Wassef W, Woda BA, Hutchinson LM, Cosar EF. Somatic molecular analysis augments cytologic evaluation of pancreatic cyst fluids as a diagnostic tool. Oncotarget. 2019 Jun 18; 10(40):4026-4037. PMID: 31258847.
      Citations: 2     Fields:    
    12. Zhu X, Salhab M, Tomaszewicz K, Meng X, Mathew C, Bathini V, Switzer B, Walter O, Cosar EF, Wang X, Lambert LA, Hutchinson LM. Heterogeneous mutational profile and prognosis conferred by TP53 mutations in appendiceal mucinous neoplasms. Hum Pathol. 2019 03; 85:260-269. PMID: 30458197.
      Citations: 2     Fields:    Translation:Humans
    13. Liu Q, Cornejo KM, Cheng L, Hutchinson L, Wang M, Zhang S, Tomaszewicz K, Cosar EF, Woda BA, Jiang Z. Next-Generation Sequencing to Detect Deletion of RB1 and ERBB4 Genes in Chromophobe Renal Cell Carcinoma: A Potential Role in Distinguishing Chromophobe Renal Cell Carcinoma from Renal Oncocytoma. Am J Pathol. 2018 04; 188(4):846-852. PMID: 29353061.
      Citations: 6     Fields:    Translation:Humans
    14. Sakhdari A, Hutchinson L, Vaskas N, Scott M, Cosar EF, Al-Turkmani R. Routine Analysis of Lipase in Cyst Fluid Is Unnecessary and Does Not Help Discriminate Between Nonneoplastic and Neoplastic Cystic Pancreatic Lesions. Pancreas. 2017 Mar; 46(3):e25-e27. PMID: 28187114.
      Citations:    Fields:    Translation:Humans
    15. Cornejo KM, Cosar EF, O?Donnell P. Cutaneous Intralymphatic Histiocytosis Associated With Lung Adenocarcinoma. Am J Dermatopathol. 2016 Jul; 38(7):568-70. PMID: 27322793.
      Citations:    Fields:    Translation:HumansCells
    16. Zhou AG, Liu Y, Cyr MS, Garver J, Woda BA, Cosar EF, Hutchinson LM. Role of Tetrasomy for the Diagnosis of Urothelial Carcinoma Using UroVysion Fluorescent In Situ Hybridization. Arch Pathol Lab Med. 2016 Jun; 140(6):552-9. PMID: 27232347.
      Citations: 2     Fields:    Translation:Humans
    17. Kamionek M, Ahmadi Moghaddam P, Sakhdari A, Kovach AE, Welch M, Meng X, Dresser K, Tomaszewicz K, Cosar EF, Mark EJ, Fraire AE, Hutchinson L. Mutually exclusive extracellular signal-regulated kinase pathway mutations are present in different stages of multi-focal pulmonary Langerhans cell histiocytosis supporting clonal nature of the disease. Histopathology. 2016 Sep; 69(3):499-509. PMID: 26915300.
      Citations: 14     Fields:    Translation:HumansCells
    18. Moghaddam PA, Virk R, Sakhdari A, Prasad ML, Cosar EF, Khan A. Five Top Stories in Thyroid Pathology. Arch Pathol Lab Med. 2016 Feb; 140(2):158-70. PMID: 26910221.
      Citations: 1     Fields:    Translation:Humans
    19. Cornejo KM, Deng A, Wu H, Cosar EF, Khan A, St Cyr M, Tomaszewicz K, Dresser K, O'Donnell P, Hutchinson L. The utility of MYC and FLT4 in the diagnosis and treatment of postradiation atypical vascular lesion and angiosarcoma of the breast. Hum Pathol. 2015 Jun; 46(6):868-75. PMID: 25864386.
      Citations: 12     Fields:    Translation:Humans
    20. Rosenblum F, Hutchinson LM, Garver J, Woda B, Cosar E, Kurian EM. Cytology specimens offer an effective alternative to formalin-fixed tissue as demonstrated by novel automated detection for ALK break-apart FISH testing and immunohistochemistry in lung adenocarcinoma. Cancer Cytopathol. 2014 Nov; 122(11):810-21. PMID: 25099128.
      Citations: 8     Fields:    Translation:Humans
    21. Cornejo KM, Hutchinson L, Deng A, Tomaszewicz K, Welch M, Lyle S, Dresser K, Cosar EF. BRAF/KRAS gene sequencing of sebaceous neoplasms after mismatch repair protein analysis. Hum Pathol. 2014 Jun; 45(6):1213-20. PMID: 24767862.
      Citations: 3     Fields:    Translation:HumansCells
    22. Cornejo KM, Kandil D, Khan A, Cosar EF. Theranostic and molecular classification of breast cancer. Arch Pathol Lab Med. 2014 Jan; 138(1):44-56. PMID: 24377811.
      Citations: 15     Fields:    Translation:Humans
    23. Yang X, Kandil D, Cosar EF, Khan A. Fibroepithelial tumors of the breast: pathologic and immunohistochemical features and molecular mechanisms. Arch Pathol Lab Med. 2014 Jan; 138(1):25-36. PMID: 24377809.
      Citations: 16     Fields:    Translation:Humans
    24. Zhou AG, Hutchinson LM, Cosar EF. Urine Cytopathology and Ancillary Methods. Surg Pathol Clin. 2014 Mar; 7(1):77-88. PMID: 26839270.
      Citations: 4     Fields:    
    25. Cornejo KM, Hutchinson L, Cosar EF, Smith T, Tomaszewicz K, Dresser K, Deng A. Is it a primary or metastatic melanocytic neoplasm of the central nervous system?: A molecular based approach. Pathol Int. 2013 Nov; 63(11):559-64. PMID: 24274719.
      Citations: 2     Fields:    Translation:HumansCells
    26. Zhou AG, Owens CL, Cosar EF, Jiang Z. Clinical implications of current developments in genitourinary pathology. Arch Pathol Lab Med. 2013 Jul; 137(7):887-93. PMID: 23808460.
      Citations: 2     Fields:    Translation:Humans
    27. Morgan TK, Hardiman K, Corless CL, White SL, Bonnah R, Van de Vrugt H, Sheppard BC, Grompe M, Cosar EF, Streeter PR. Human pancreatic cancer fusion 2 (HPC2) 1-B3: a novel monoclonal antibody to screen for pancreatic ductal dysplasia. Cancer Cytopathol. 2013 Jan; 121(1):37-46. PMID: 22811080.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    28. Kurian EM, Caporelli ML, Baker S, Woda B, Cosar EF, Hutchinson L. Cervista HR and HPV 16/18 assays vs hybrid capture 2 assay: outcome comparison in women with negative cervical cytology. Am J Clin Pathol. 2011 Nov; 136(5):808-16. PMID: 22031321.
      Citations: 9     Fields:    Translation:HumansCells
    29. Yantiss RK, Cosar E, Fischer AH. Use of IMP3 in identification of carcinoma in fine needle aspiration biopsies of pancreas. Acta Cytol. 2008 Mar-Apr; 52(2):133-8. PMID: 18499984.
      Citations: 9     Fields:    Translation:HumansCells
    30. Mercader M, Sengupta S, Bodner BK, Manecke RG, Cosar EF, Moser MT, Ballman KV, Wojcik EM, Kwon ED. Early effects of pharmacological androgen deprivation in human prostate cancer. BJU Int. 2007 Jan; 99(1):60-7. PMID: 17227493.
      Citations: 13     Fields:    Translation:Humans
    31. Reddy D, Salomon C, Demos TC, Cosar E. Mesenteric lymph node cavitation in celiac disease. AJR Am J Roentgenol. 2002 Jan; 178(1):247. PMID: 11756139.
      Citations: 4     Fields:    Translation:Humans
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