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Yoshiko Usami PhD

InstitutionUMass Chan Medical School
DepartmentMolecular, Cell and Cancer Biology
AddressUMass Chan Medical School
364 Plantation Street LRB
Worcester MA 01605
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMolecular, Cell and Cancer Biology

    InstitutionT.H. Chan School of Medicine
    DepartmentProgram in Molecular Medicine

    Collapse Biography 
    Collapse education and training
    Gifu University, Gifu, , JapanMSPharmaceutical Science
    Gifu University, Gifu, , JapanPHDPharmaceutical Science

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Olety B, Usami Y, Wu Y, Peters P, G?ttlinger H. AP-2 Adaptor Complex-Dependent Enhancement of HIV-1 Replication by Nef in the Absence of the Nef/AP-2 Targets SERINC5 and CD4. mBio. 2023 02 28; 14(1):e0338222. PMID: 36622146.
      Citations:    Fields:    Translation:HumansCells
    2. Olety B, Peters P, Wu Y, Usami Y, G?ttlinger H. HIV-1 propagation is highly dependent on basal levels of the restriction factor BST2. Sci Adv. 2021 Oct 29; 7(44):eabj7398. PMID: 34714669.
      Citations: 4     Fields:    
    3. Dai W, Usami Y, Wu Y, G?ttlinger H. A Long Cytoplasmic Loop Governs the Sensitivity of the Anti-viral Host Protein SERINC5 to HIV-1 Nef. Cell Rep. 2018 01 23; 22(4):869-875. PMID: 29386131.
      Citations: 29     Fields:    Translation:HumansCells
    4. Miyauchi K, Sugimoto-Ishige A, Harada Y, Adachi Y, Usami Y, Kaji T, Inoue K, Hasegawa H, Watanabe T, Hijikata A, Fukuyama S, Maemura T, Okada-Hatakeyama M, Ohara O, Kawaoka Y, Takahashi Y, Takemori T, Kubo M. Protective neutralizing influenza antibody response in the absence of T follicular helper cells. Nat Immunol. 2016 Dec; 17(12):1447-1458. PMID: 27798619.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    5. Usami Y, Wu Y, G?ttlinger HG. SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef. Nature. 2015 Oct 08; 526(7572):218-23. PMID: 26416733.
      Citations: 257     Fields:    Translation:HumansCells
    6. Usami Y, Popov S, G?ttlinger HG. The Nef-like effect of murine leukemia virus glycosylated gag on HIV-1 infectivity is mediated by its cytoplasmic domain and depends on the AP-2 adaptor complex. J Virol. 2014 Mar; 88(6):3443-54. PMID: 24403584.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    7. Usami Y, G?ttlinger H. HIV-1 Nef responsiveness is determined by Env variable regions involved in trimer association and correlates with neutralization sensitivity. Cell Rep. 2013 Nov 14; 5(3):802-12. PMID: 24209751.
      Citations: 34     Fields:    Translation:HumansCells
    8. Weissenhorn W, Miguet N, Aschman N, Renesto P, Usami Y, Gottlinger HG. Structural basis of tetherin function. Curr HIV Res. 2012 Jun; 10(4):298-306. PMID: 22524178.
      Citations: 4     Fields:    Translation:HumansCells
    9. Martinelli N, Hartlieb B, Usami Y, Sabin C, Dordor A, Miguet N, Avilov SV, Ribeiro EA, G?ttlinger H, Weissenhorn W. CC2D1A is a regulator of ESCRT-III CHMP4B. J Mol Biol. 2012 May 25; 419(1-2):75-88. PMID: 22406677.
      Citations: 33     Fields:    Translation:HumansCells
    10. Usami Y, Popov S, Weiss ER, Vriesema-Magnuson C, Calistri A, G?ttlinger HG. Regulation of CHMP4/ESCRT-III function in human immunodeficiency virus type 1 budding by CC2D1A. J Virol. 2012 Apr; 86(7):3746-56. PMID: 22258254.
      Citations: 17     Fields:    Translation:HumansCells
    11. Solomons J, Sabin C, Poudevigne E, Usami Y, Hulsik DL, Macheboeuf P, Hartlieb B, G?ttlinger H, Weissenhorn W. Structural basis for ESCRT-III CHMP3 recruitment of AMSH. Structure. 2011 Aug 10; 19(8):1149-59. PMID: 21827950.
      Citations: 27     Fields:    Translation:HumansCells
    12. Hinz A, Miguet N, Natrajan G, Usami Y, Yamanaka H, Renesto P, Hartlieb B, McCarthy AA, Simorre JP, G?ttlinger H, Weissenhorn W. Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain. Cell Host Microbe. 2010 Apr 22; 7(4):314-323. PMID: 20399176.
      Citations: 101     Fields:    Translation:AnimalsCells
    13. Usami Y, Popov S, Popova E, Inoue M, Weissenhorn W, G G?ttlinger H. The ESCRT pathway and HIV-1 budding. Biochem Soc Trans. 2009 Feb; 37(Pt 1):181-4. PMID: 19143627.
      Citations: 64     Fields:    Translation:HumansCells
    14. Usami Y, Popov S, Popova E, G?ttlinger HG. Efficient and specific rescue of human immunodeficiency virus type 1 budding defects by a Nedd4-like ubiquitin ligase. J Virol. 2008 May; 82(10):4898-907. PMID: 18321969.
      Citations: 73     Fields:    Translation:HumansCells
    15. Usami Y, Popov S, G?ttlinger HG. Potent rescue of human immunodeficiency virus type 1 late domain mutants by ALIX/AIP1 depends on its CHMP4 binding site. J Virol. 2007 Jun; 81(12):6614-22. PMID: 17428861.
      Citations: 98     Fields:    Translation:HumansCells
    16. Zamborlini A, Usami Y, Radoshitzky SR, Popova E, Palu G, G?ttlinger H. Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 budding. Proc Natl Acad Sci U S A. 2006 Dec 12; 103(50):19140-5. PMID: 17146056.
      Citations: 106     Fields:    Translation:HumansCells
    17. Muziol T, Pineda-Molina E, Ravelli RB, Zamborlini A, Usami Y, G?ttlinger H, Weissenhorn W. Structural basis for budding by the ESCRT-III factor CHMP3. Dev Cell. 2006 Jun; 10(6):821-30. PMID: 16740483.
      Citations: 131     Fields:    Translation:HumansCells
    18. Oki T, Usami Y, Nakai M, Sagisaka M, Ito H, Nagaoka K, Mamiya N, Yamanaka K, Utsumi M, Kaneda T. Pharmacokinetics of lopinavir after administration of Kaletra in healthy Japanese volunteers. Biol Pharm Bull. 2004 Feb; 27(2):261-5. PMID: 14758049.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    19. Usami Y, Oki T, Nakai M, Sagisaka M, Kaneda T. A simple HPLC method for simultaneous determination of lopinavir, ritonavir and efavirenz. Chem Pharm Bull (Tokyo). 2003 Jun; 51(6):715-8. PMID: 12808252.
      Citations: 3     Fields:    Translation:Humans
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