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Jie Song PhD

TitleProfessor
InstitutionUMass Chan Medical School
DepartmentOrthopedics and Physical Rehabilitation
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
Phone508-334-7168
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentBiochemistry and Molecular Biotechnology

    InstitutionT.H. Chan School of Medicine
    DepartmentChemical Biology

    InstitutionT.H. Chan School of Medicine
    DepartmentOrthopedics and Physical Rehabilitation
    DivisionOrthopedics Research

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentBiophysical Chemical and Computational Biology

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentInterdisciplinary Graduate Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentMD/PhD Program

    InstitutionUMass Chan Programs, Centers and Institutes
    DepartmentChemical Biology


    Collapse Biography 
    Collapse education and training
    Fudan University, Shanghai, 31, ChinaBSChemistry
    Michigan State University, East Lansing, MI, United StatesPHDOrganic Chemistry
    Collapse awards and honors
    2022BRIDGE Fund, UMass Chan Medical School, BRIDGE Innovation & Business Development
    2022OTCV Technology Development Fund Award, University of Massachusetts
    2019BRIDGE Fund, UMass Medical School, BRIDGE Innovation & Business Development
    2017ALSF Innovation Grant award, Alex's Lemonade Stand Foundation
    2017Bassick Family Foundation Award, Worcester Foundation/Hudson Hoagland Society
    2016OTCV Technology Development Fund Award, University of Massachusetts
    2015OTCV Technology Development Fund Award, University of Massachusetts
    2015Faculty Vitality Award, UMASS Medical School
    2015J.R. Neff Award , Musculoskeletal Transplant Foundation
    2014Mel and Sandy Cutler Award, Worcester Foundation/Hudson Hoagland Society
    2013Dean’s Award for Research Mentoring and Commitment to Student Professional Advancement, GSBS/UMMS
    2013Commercial Ventures & Intellectual Property Award, University of Massachusetts
    2011Commercial Ventures & Intellectual Property Award, University of Massachusetts
    2008Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) Award, National Institutes of Health
    2008Career Enhancement Award, American Society for Bone and Mineral Research
    2007Commercial Ventures & Intellectual Property Award, University of Massachusetts
    2007Technology Investigation Award, Massachusetts Technology Transfer Center
    2007Harold M. Frost Young Investigator Award, American Society for Bone and Mineral Research

    Collapse Overview 
    Collapse overview

    Jie Song Profile Photo

    Biography

    B.S. 1995, Fudan University, P.R. China
    Ph.D. 1999, Michigan State University
    Postdoctoral Fellow 1999-2002, University of California Berkeley & Lawrence Berkeley National Laboratory
    Staff Scientist 2002-2006, Lawrence Berkeley National Laboratory

    Research Interests

    With an aging population, the demand for synthetic tissue scaffolds assisting the regenerative reconstruction of skeletal defects resulting from trauma, cancer and metabolic diseases is rising. Our lab is interested in 1) designing functional synthetic matrices to guide bone and cartilage tissue regeneration; 2) identifying and implementaing novel strategies for modulating synthetic niche properties as means to regulate stem cell fate; 3) improving osteointegration of and reducing periprosthetic infections associated with orthopedic metallic implants. Many of the synthetic matrices we designed are programmed with unique physical properties to facilitate surgical delivery (injectable formulations; minimally invasive delivery, and stable in vivo fixation), predictive in vivo degradation profiles, tunable biomechanical cues, and spatially controlled presentation and temporally controlled release of bioactive factors for regulating fate of stem/progenitor cells within the synthetic niche.

     

     Current Lab Members:

    Song Lab 2024 Summer

    2024 Song Lab BBQ

    August 2024, Lab BBQ @ Lake Quinsigamond

    Back: Shing-Yun, Jordan, Jie, Rahul, Andrew, Fei, Aidan

    Front: Naomi, Olivia, Paula

    Song Lab 2017 ORS

    San Diego (ORS meeting), March 2017

    L to R: Yu, Ben, Tera, Jordan, Jie & Henry


    Collapse Rotation Projects

    Potential Rotation Projects

    1. Degradable viscoelastic synthetic hydrogels for therapeutic cell delivery
    2. Prophylactic implant coatings against periprosthetic infections
    3. Shape memory polymer-based composite bone grafts

    Collapse Post Docs

    A postdoc opening is available to participate in the development of functional biomaterials for skeletal tissue regeneration focusing on immune regulation and inflammation resolution. The fellow is expected to work both independently and collaboratively, and contribute to a productive and cordial team environment. Salary follows NIH postdoctoral fellowship compensation guideline.

    Requirements:
    • Recent PhD in Chemical Biology, Bioengineering, Biology, or Polymer Science
    • Expertise in examining cell-material interactions (e.g. immune cell regulations, stem cell lineage commitment) OR synthesis and characterization of functional biomaterials expected
    • Experience with animal studies desired but not required
    • Self-motivated and organized, good written and oral communication skills.

    To apply for this position: Send your CV and the contact information for three references to Jie.Song@umassmed.edu


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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chang SY, McAnena AP, Kim J, Song J. Tuning Hyaluronic Acid Microstructures by Engineered Amphiphilicity: From Dynamically Cross-Linked Gels to Multilayered Nanoparticles. ACS Appl Mater Interfaces. 2025 May 25. PMID: 40415248.
      Citations:    
    2. Feiyang Chen, Naomi E. Schiffer, Jie Song. Animal Models of Orthopedic Implant-Associated Infections and Revisions. ACS Biomaterials Science & Engineering. 2025; 11:2052-2068. View Publication.
    3. Feiyang Chen, Jordan D. Skelly, Shing-Yun Chang, Jie Song. Triggered Release of Ampicillin from Metallic Implant Coatings for Combating Periprosthetic Infections. ACS Applied Materials & Interfaces. 2024; 16:24421-24430. View Publication.
    4. Jordan D. Skelly, Feiyang Chen, Shing-Yun Chang, Rewati R. Ujjwal, Ananta Ghimire, David C. Ayers and Jie Song. Tuning On-demand Releases of Vancomycin Covalently Tethered to Implant Coatings through the Chemical Modification of a Micrococcal-Nuclease-Sensitive Oligonucleotide Linker. ACS Appl. Mater. Interfaces. 2023; 15:37174-37183. View Publication.
    5. Xiaowen Xu, Jordan Skelly and Jie Song. Chemically crosslinked amphiphilic degradable shape memory polymer nanocomposites with readily tuned physical, mechanical, and biological properties. ACS Appl Mater Interfaces. 2023; 15:2693-2704. View Publication.
    6. Chloe Herczeg and Jie Song. Sterilization of Polymeric Implants: Challenges and Opportunities. ACS Applied Bio Materials. 2022; 5:5077-5088. View Publication.
    7. Xiaowen Xu and Jie Song. Bone Tissue Engineering: Bench to Bedside Using 3D Printing (Fernando P.S. Guastaldi and Bhushan Mahadik Ed.). Bone Grafting in the Regenerative Reconstruction of Critical-Size Long Bone Segmental Defects. 2022; 165-192 (doi 10.1007/978-3-030. View Publication.
    8. Yu Tan and Jie Song. Independent and Synergistic Modulations of Viscoelasticity and Stiffness of Dynamically Crosslinked Cell-encapsulating ClickGels by Covalently Tethered Polymer Brushes. Biomacromolecules. 2021; 22(8):3408-3415. View Publication.
    9. Xiaowen Xu#, Jing Zhang#, Tera Filion, Ali Akalin and Jie Song (#equal contribution). Modulating mechanical and shape-memory properties while mitigating degradation-induced inflammation of polylactides by pendant aspirin incorporation. ACS Appl. Mater. Interfaces. 2021; 13(19):22271-22281. View Publication.
    10. Ananta Ghimire and Jie Song. Anti-periprosthetic infection strategies: from implant surface topographical engineering to smart drug-releasing coatings. ACS Appl. Mater. Interfaces. 2021; 13(18):20921–20937. View Publication.
    11. Xiaowen Xu and Jie Song. Segmental long bone regeneration guided by degradable synthetic polymeric scaffolds. Biomaterials Translational. 2020; 1(1):33-45. View Publication.
    12. Ben Zhang, Jordan D. Skelly, Benjamin Braun, David C. Ayers and Jie Song. Surface-Grafted Zwitterionic Polymers Improve the Efficacy of a Single Antibiotic Injection in Suppressing Staphylococcus aureus Periprosthetic Infections. ACS Appl Bio Mater. 2020; 3(9):5896-5904. View Publication.
    13. Ghimire A, Skelly JD, Song J. Micrococcal-Nuclease-Triggered On-Demand Release of Vancomycin from Intramedullary Implant Coating Eradicates Staphylococcus aureus Infection in Mouse Femoral Canals. ACS Cent Sci. 2019 Dec 26; 5(12):1929-1936. PMID: 31893222.
      Citations:    
    14. Zhang B, Braun BM, Skelly JD, Ayers DC, Song J. Significant Suppression of Staphylococcus aureus Colonization on Intramedullary Ti6Al4V Implants Surface-Grafted with Vancomycin-Bearing Polymer Brushes. ACS Appl Mater Interfaces. 2019 Aug 14; 11(32):28641-28647. PMID: 31313901.
      Citations: 10     Fields:    Translation:AnimalsCells
    15. Ben Zhang, Jordan D. Skelly, Jacob Maalouf, David C. Ayers and Jie Song. Multi-functional scaffolds for facile implantation, spontaneous fixation and accelerated long bone regeneration in rodents. Science Translational Medicine. 2019; 11(502):eaau7411. View Publication.
    16. Tan Y, Huang H, Ayers DC, Song J. Modulating Viscoelasticity, Stiffness, and Degradation of Synthetic Cellular Niches via Stoichiometric Tuning of Covalent versus Dynamic Noncovalent Cross-Linking. ACS Cent Sci. 2018 Aug 22; 4(8):971-981. PMID: 30159394.
      Citations:    
    17. Henry Huang, Yu Tan, David C. Ayers and Jie Song. Anionic and zwitterionic residues modulate stiffness of photo-crosslinked hydrogels and cellular behavior of encapsulated chondrocytes. ACS Biomater Sci Eng. 2018; 4:1843-1851. View Publication.
    18. Ben Zhang and Jie Song. 3D Printed Biomaterials for Guided Tissue Regeneration. Small Methods. 2018; DOI: 10.1002/smtd.201700306. View Publication.
    19. Filion TM, Skelly JD, Huang H, Greiner DL, Ayers DC, Song J. Impaired osteogenesis of T1DM bone marrow-derived stromal cells and periosteum-derived cells and their differential in-vitro responses to growth factor rescue. Stem Cell Res Ther. 2017 03 11; 8(1):65. PMID: 28283030.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    20. Huang H, Skelly JD, Ayers DC, Song J. Age-dependent Changes in the Articular Cartilage and Subchondral Bone of C57BL/6 Mice after Surgical Destabilization of Medial Meniscus. Sci Rep. 2017 02 09; 7:42294. PMID: 28181577.
      Citations: 41     Fields:    Translation:Animals
    21. Zhang B, DeBartolo JE, Song J. Shape Recovery with Concomitant Mechanical Strengthening of Amphiphilic Shape Memory Polymers in Warm Water. ACS Appl Mater Interfaces. 2017 Feb 08; 9(5):4450-4456. PMID: 28125208.
      Citations: 4     Fields:    
    22. Ben Zhang, Tera M. Filion, Artem B. Kutikov and Jie Song. Facile Stem Cell Delivery to Bone Grafts Enabled by Smart Shape Recovery and Stiffening of Degradable Synthetic Periosteal Membranes. Adv. Funct. Mater. 2017; 1604784. View Publication.
    23. Huang H, Veien ES, Zhang H, Ayers DC, Song J. Skeletal Characterization of Smurf2-Deficient Mice and In Vitro Analysis of Smurf2-Deficient Chondrocytes. PLoS One. 2016; 11(1):e0148088. PMID: 26815610.
      Citations: 12     Fields:    Translation:AnimalsCells
    24. Liu P, Song J. Well-controlled ATRP of 2-(2-(2-Azidoethyoxy)ethoxy)ethyl Methacrylate for High-density Click Functionalization of Polymers and Metallic Substrates. J Polym Sci A Polym Chem. 2016 May 01; 54(9):1268-1277. PMID: 27616816.
      Citations:    
    25. Youssefian S, Liu P, Askarinejad S, Shalchy F, Song J, Rahbar N. Experimental and numerical measurements of adhesion energies between PHEMA and PGLYMA with hydroxyapatite crystal. Bioinspir Biomim. 2015 Jul 16; 10(4):046011. PMID: 26179911.
      Citations:    Fields:    Translation:Cells
    26. Kutikov AB, Song J. Biodegradable PEG-Based Amphiphilic Block Copolymers for Tissue Engineering Applications. ACS Biomater Sci Eng. 2015 Jul 13; 1(7):463-480. PMID: 27175443.
      Citations: 29     Fields:    
    27. Jianwen Xu and Jie Song. Shape Memory Polymers for Biomedical Applications (A volume in Woodhead Publishing Series in Biomaterials), L’Hocine Yahia Ed. Chapter 10: Polylactic acid (PLA)-based shape-memory materials for biomedical applications. 2015. View Publication.
    28. Kutikov AB, Skelly JD, Ayers DC, Song J. Templated repair of long bone defects in rats with bioactive spiral-wrapped electrospun amphiphilic polymer/hydroxyapatite scaffolds. ACS Appl Mater Interfaces. 2015 Mar 04; 7(8):4890-901. PMID: 25695310.
      Citations: 8     Fields:    Translation:AnimalsCells
    29. Liu P, Emmons E, Song J. A comparative study of zwitterionic ligands-mediated mineralization and the potential of mineralized zwitterionic matrices for bone tissue engineering. J Mater Chem B. 2014 Nov 21; 2(43):7524-7533. PMID: 25558374.
      Citations: 2     Fields:    
    30. Kutikov AB, Reyer KA, Song J. Shape Memory Performance of Thermoplastic Amphiphilic Triblock Copolymer poly(D,L-lactic acid-co-ethylene glycol-co-D,L-lactic acid) (PELA)/Hydroxyapatite Composites. Macromol Chem Phys. 2014 Dec; 215(24):2482-2490. PMID: 26457046.
      Citations:    
    31. Kutikov AB, Gurijala A, Song J. Rapid prototyping amphiphilic polymer/hydroxyapatite composite scaffolds with hydration-induced self-fixation behavior. Tissue Eng Part C Methods. 2015 Mar; 21(3):229-41. PMID: 25025950.
      Citations: 5     Fields:    Translation:AnimalsCells
    32. Skelly JD, Lange J, Filion TM, Li X, Ayers DC, Song J. Vancomycin-bearing synthetic bone graft delivers rhBMP-2 and promotes healing of critical rat femoral segmental defects. Clin Orthop Relat Res. 2014 Dec; 472(12):4015-23. PMID: 25099263.
      Citations: 5     Fields:    Translation:Animals
    33. Liu P, Skelly JD, Song J. Three-dimensionally presented anti-fouling zwitterionic motifs sequester and enable high-efficiency delivery of therapeutic proteins. Acta Biomater. 2014 Oct; 10(10):4296-303. PMID: 24956565.
      Citations: 4     Fields:    Translation:HumansAnimals
    34. Liu P, Domingue E, Ayers DC, Song J. Modification of Ti6Al4V substrates with well-defined zwitterionic polysulfobetaine brushes for improved surface mineralization. ACS Appl Mater Interfaces. 2014 May 28; 6(10):7141-52. PMID: 24828749.
      Citations: 8     Fields:    Translation:AnimalsCells
    35. Zhang J, Song J. Amphiphilic degradable polymers for immobilization and sustained delivery of sphingosine 1-phosphate. Acta Biomater. 2014 Jul; 10(7):3079-90. PMID: 24631657.
      Citations: 5     Fields:    Translation:HumansCells
    36. Xu J, Feng E, Song J. Renaissance of Aliphatic Polycarbonates: New Techniques and Biomedical Applications. J Appl Polym Sci. 2014 Mar 05; 131(5). PMID: 24994939.
      Citations:    
    37. Xu J, Feng E, Song J. Bioorthogonally cross-linked hydrogel network with precisely controlled disintegration time over a broad range. J Am Chem Soc. 2014 Mar 19; 136(11):4105-8. PMID: 24597638.
      Citations: 5     Fields:    Translation:Cells
    38. Filion TM, Song J. A sulfated nanofibrous mesh supporting the osteogenic differentiation of periosteum-derived cells. J Biomater Tissue Eng. 2013 Aug 01; 3(4):486-493. PMID: 25309819.
      Citations:    
    39. Li X, Xu J, Filion TM, Ayers DC, Song J. pHEMA-nHA encapsulation and delivery of vancomycin and rhBMP-2 enhances its role as a bone graft substitute. Clin Orthop Relat Res. 2013 Aug; 471(8):2540-7. PMID: 23070662.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    40. Kutikov AB, Song J. An amphiphilic degradable polymer/hydroxyapatite composite with enhanced handling characteristics promotes osteogenic gene expression in bone marrow stromal cells. Acta Biomater. 2013 Sep; 9(9):8354-64. PMID: 23791675.
      Citations: 17     Fields:    Translation:AnimalsCells
    41. Zhao L, Kutikov A, Shen J, Duan C, Song J, Han G. Stem cell labeling using polyethylenimine conjugated (a-NaYbF4:Tm3+)/CaF2 upconversion nanoparticles. Theranostics. 2013; 3(4):249-57. PMID: 23606911.
      Citations: 19     Fields:    Translation:AnimalsCells
    42. Liu P, Song J. Sulfobetaine as a zwitterionic mediator for 3D hydroxyapatite mineralization. Biomaterials. 2013 Mar; 34(10):2442-54. PMID: 23332320.
      Citations: 10     Fields:    Translation:AnimalsCells
    43. Chen G, Shen J, Ohulchanskyy TY, Patel NJ, Kutikov A, Li Z, Song J, Pandey RK, Agren H, Prasad PN, Han G. (a-NaYbF4:Tm(3+))/CaF2 core/shell nanoparticles with efficient near-infrared to near-infrared upconversion for high-contrast deep tissue bioimaging. ACS Nano. 2012 Sep 25; 6(9):8280-7. PMID: 22928629.
      Citations: 95     Fields:    Translation:AnimalsCells
    44. Jianwen Xu and Jie Song. Engineering Polylactic Acid with Thermal-responsive Shape Memory Effect for Medical Applications, Chapter 11. Polylactic Acid: Synthesis, Properties and Applications, Vincenzo Piemonte Ed.Polylactic Acid: Synthesis, Properties and Applications, Vincenzo Piemonte Ed. 2012.
    45. Xu J, Filion TM, Prifti F, Song J. Cytocompatible poly(ethylene glycol)-co-polycarbonate hydrogels cross-linked by copper-free, strain-promoted click chemistry. Chem Asian J. 2011 Oct 04; 6(10):2730-7. PMID: 21954076.
      Citations: 26     Fields:    Translation:AnimalsCells
    46. Jianwen Xu and Jie Song. Biomedical Engineering - Frontiers and Challenges, Reza Fazel-Rezai Ed. Chapter 6: Thermal responsive shape memory polymers for biomedical applications. 2011; 125-142. View Publication.
    47. Tera M. Filion and Jie Song. Biomedical Engineering - Frontiers and Challenges, Reza Fazel-Rezai Ed. Chapter 12: Scalable functional bone substitutes: strategic integration of key structural elements of bone in synthetic biomaterials. 2011; 233-248. View Publication.
    48. Liu P, Smits J, Ayers DC, Song J. Surface mineralization of Ti6Al4V substrates with calcium apatites for the retention and local delivery of recombinant human bone morphogenetic protein-2. Acta Biomater. 2011 Sep; 7(9):3488-95. PMID: 21651998.
      Citations: 6     Fields:    Translation:HumansAnimals
    49. Xu J, Prifti F, Song J. A Versatile Monomer for Preparing Well-Defined Functional Polycarbonates and Poly(ester-carbonates). Macromolecules. 2011 Apr 26; 44(8):2660-2667. PMID: 21686053.
      Citations: 9     Fields:    
    50. Filion TM, Kutikov A, Song J. Chemically modified cellulose fibrous meshes for use as tissue engineering scaffolds. Bioorg Med Chem Lett. 2011 Sep 01; 21(17):5067-70. PMID: 21536439.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    51. Chung WJ, Kwon KY, Song J, Lee SW. Evolutionary screening of collagen-like peptides that nucleate hydroxyapatite crystals. Langmuir. 2011 Jun 21; 27(12):7620-8. PMID: 21291244.
      Citations: 20     Fields:    Translation:Cells
    52. Filion TM, Xu J, Prasad ML, Song J. In vivo tissue responses to thermal-responsive shape memory polymer nanocomposites. Biomaterials. 2011 Feb; 32(4):985-91. PMID: 21040968.
      Citations: 10     Fields:    Translation:AnimalsCells
    53. Filion TM, Li X, Mason-Savas A, Kreider JM, Goldstein SA, Ayers DC, Song J. Elastomeric osteoconductive synthetic scaffolds with acquired osteoinductivity expedite the repair of critical femoral defects in rats. Tissue Eng Part A. 2011 Feb; 17(3-4):503-11. PMID: 20818999.
      Citations: 15     Fields:    Translation:Animals
    54. Xu J, Song J. High performance shape memory polymer networks based on rigid nanoparticle cores. Proc Natl Acad Sci U S A. 2010 Apr 27; 107(17):7652-7. PMID: 20375285.
      Citations: 9     Fields:    Translation:Cells
    55. Xu J, Li X, Lian JB, Ayers DC, Song J. Sustained and localized in vitro release of BMP-2/7, RANKL, and tetracycline from FlexBone, an elastomeric osteoconductive bone substitute. J Orthop Res. 2009 Oct; 27(10):1306-11. PMID: 19350632.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    56. Song J, Xu J, Filion T, Saiz E, Tomsia AP, Lian JB, Stein GS, Ayers DC, Bertozzi CR. Elastomeric high-mineral content hydrogel-hydroxyapatite composites for orthopedic applications. J Biomed Mater Res A. 2009 Jun 15; 89(4):1098-107. PMID: 18546185.
      Citations: 23     Fields:    Translation:AnimalsCells
    57. Su J, Iomdina E, Tarutta E, Ward B, Song J, Wildsoet CF. Effects of poly(2-hydroxyethyl methacrylate) and poly(vinyl-pyrrolidone) hydrogel implants on myopic and normal chick sclera. Exp Eye Res. 2009 Mar; 88(3):445-57. PMID: 19109950.
      Citations: 5     Fields:    Translation:AnimalsCells
    58. Song J. A chemical and engineering approach towards "smart" synthetic bone grafts. J Musculoskelet Neuronal Interact. 2007 Oct-Dec; 7(4):325. PMID: 18094494.
      Citations:    Fields:    Translation:HumansAnimalsCells
    59. Kaufman JD, Song J, Klapperich CM. Nanomechanical analysis of bone tissue engineering scaffolds. J Biomed Mater Res A. 2007 Jun 01; 81(3):611-23. PMID: 17187400.
      Citations: 3     Fields:    
    60. Song J, Malathong V, Bertozzi CR. Mineralization of synthetic polymer scaffolds: a bottom-up approach for the development of artificial bone. J Am Chem Soc. 2005 Mar 16; 127(10):3366-72. PMID: 15755154.
      Citations: 38     Fields:    
    61. Jie Song and Carolyn R. Bertozzi. Functional polymers for bone tissue engineering applications. Handbook of Nanostructured Biomaterials and Their Applications in Nanobiotechnology, H. S. Nalwa Ed. 2005; 2:371-392.
    62. Antoni P. Tomsia, Eduardo Saiz, Jie Song and Carolyn Bertozzi. Biomimetic Bonelike Composites and Novel Bioactive Glass Coatings. Adv. Eng. Mater. 2005; 7(11):999-1004. View Publication.
    63. Jie Song and , Carolyn R. Bertozzi. Functional Hydrogel-Biomineral Composites Inspired by Natural Bone, Chapter 7. Polymer Biocatalysis and Biomaterials. 2005; 900:96-106. View Publication.
    64. Song J, Cisar JS, Bertozzi CR. Functional self-assembling bolaamphiphilic polydiacetylenes as colorimetric sensor scaffolds. J Am Chem Soc. 2004 Jul 14; 126(27):8459-65. PMID: 15238003.
      Citations: 1     Fields:    
    65. Cheng Q, Zhu S, Song J, Zhang N. Functional lipid microstructures immobilized on a gold electrode for voltammetric biosensing of cholera toxin. Analyst. 2004 Apr; 129(4):309-14. PMID: 15042161.
      Citations: 4     Fields:    
    66. Jie Song, Raymond C. Stevens and Quan Cheng. Functional Amphiphilic and Bolaamphiphilic Poly(diacetylene) Assemblies with Controlled Optical and Morphological Properties, Chapter 7. Chromogenic Phenomena in Polymers. 2004; 888:96-109. View Publication.
    67. Jie Song, Julia Chen, Catherine M. Klapperich, Vincent Eng and Carolyn R. Bertozzi. Functional glass slides for in vitro evaluation of interactions between osteosarcoma TE85 cells and mineral-binding ligands. J. Mater. Chem. 2004; 14:2643-2648. View Publication.
    68. Song J, Saiz E, Bertozzi CR. A new approach to mineralization of biocompatible hydrogel scaffolds: an efficient process toward 3-dimensional bonelike composites. J Am Chem Soc. 2003 Feb 05; 125(5):1236-43. PMID: 12553825.
      Citations: 38     Fields:    Translation:Cells
    69. Jie Song, Eduardo Saiz and Carolyn R. Bertozzi. Preparation of pHEMA-CP composites with high interfacial adhesion via template-driven mineralization. J. Eur. Ceram. Soc. 2003; 23(15):2905-2919. View Publication.
    70. Jie Song, Quan Cheng and Raymond C. Stevens. Morphological manipulation of bolaamphiphilic polydiacetylene assemblies by controlled lipid doping. Chem. Phys. Lipids. 2002; 114:203-214. View Publication.
    71. Jie Song, Quan Cheng, Shimin Zhu and Raymond C. Stevens. “Smart” Materials for Biosensing Devices: Cell-Mimicking Supramolecular Assemblies and Colorimetric Detection of Pathogenic Agents. Biomedical Microdevices. 2002; 4(3):213-221. View Publication.
    72. Song J, Cheng Q, Kopta S, Stevens RC. Modulating artificial membrane morphology: pH-induced chromatic transition and nanostructural transformation of a bolaamphiphilic conjugated polymer from blue helical ribbons to red nanofibers. J Am Chem Soc. 2001 Apr 11; 123(14):3205-13. PMID: 11457054.
      Citations: 9     Fields:    Translation:Cells
    73. Jie Song and Rawle I. Hollingsworth. Homochiral 4-Hydroxy-5-hexenoic Acids and Their Derivatives and Homologues from Carbohydrates. Tetrahedron: Asymmetry. 2001; 12:387-391. View Publication.
    74. Jie Song and Rawle I. Hollingsworth. Synthesis, Conformational Analysis and Phase Characterization of a Versatile Self-assembling Monoglucosyl Diacylglycerol Analog. J. Am. Chem. Soc. 1999; 121:1851-1861. View Publication.
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