"Bone Substitutes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Synthetic or natural materials for the replacement of bones or bone tissue. They include hard tissue replacement polymers, natural coral, hydroxyapatite, beta-tricalcium phosphate, and various other biomaterials. The bone substitutes as inert materials can be incorporated into surrounding tissue or gradually replaced by original tissue.
Descriptor ID |
D018786
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MeSH Number(s) |
D25.130.325 J01.637.051.130.325
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Concept/Terms |
Bone Substitutes- Bone Substitutes
- Replacement Material, Bone
- Replacement Materials, Bone
- Materials, Bone Replacement
- Bone Substitute
- Substitute, Bone
- Substitutes, Bone
- Bone Replacement Material
- Material, Bone Replacement
- Bone Replacement Materials
|
Below are MeSH descriptors whose meaning is more general than "Bone Substitutes".
Below are MeSH descriptors whose meaning is more specific than "Bone Substitutes".
This graph shows the total number of publications written about "Bone Substitutes" by people in this website by year, and whether "Bone Substitutes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2003 | 1 | 0 | 1 |
2005 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2013 | 2 | 0 | 2 |
2014 | 2 | 0 | 2 |
2015 | 1 | 0 | 1 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Bone Substitutes" by people in Profiles.
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Cheng L, Suresh K S, He H, Rajput RS, Feng Q, Ramesh S, Wang Y, Krishnan S, Ostrovidov S, Camci-Unal G, Ramalingam M. 3D Printing of Micro- and Nanoscale Bone Substitutes: A Review on Technical and Translational Perspectives. Int J Nanomedicine. 2021; 16:4289-4319.
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Youssefian S, Liu P, Askarinejad S, Shalchy F, Song J, Rahbar N. Experimental and numerical measurements of adhesion energies between PHEMA and PGLYMA with hydroxyapatite crystal. Bioinspir Biomim. 2015 Jul 16; 10(4):046011.
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Skelly JD, Lange J, Filion TM, Li X, Ayers DC, Song J. Vancomycin-bearing synthetic bone graft delivers rhBMP-2 and promotes healing of critical rat femoral segmental defects. Clin Orthop Relat Res. 2014 Dec; 472(12):4015-23.
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Kaiser MG, Groff MW, Watters WC, Ghogawala Z, Mummaneni PV, Dailey AT, Choudhri TF, Eck JC, Sharan A, Wang JC, Dhall SS, Resnick DK. Guideline update for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 16: bone graft extenders and substitutes as an adjunct for lumbar fusion. J Neurosurg Spine. 2014 Jul; 21(1):106-32.
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Li X, Xu J, Filion TM, Ayers DC, Song J. pHEMA-nHA encapsulation and delivery of vancomycin and rhBMP-2 enhances its role as a bone graft substitute. Clin Orthop Relat Res. 2013 Aug; 471(8):2540-7.
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Kutikov AB, Song J. An amphiphilic degradable polymer/hydroxyapatite composite with enhanced handling characteristics promotes osteogenic gene expression in bone marrow stromal cells. Acta Biomater. 2013 Sep; 9(9):8354-64.
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Filion TM, Li X, Mason-Savas A, Kreider JM, Goldstein SA, Ayers DC, Song J. Elastomeric osteoconductive synthetic scaffolds with acquired osteoinductivity expedite the repair of critical femoral defects in rats. Tissue Eng Part A. 2011 Feb; 17(3-4):503-11.
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Xu J, Li X, Lian JB, Ayers DC, Song J. Sustained and localized in vitro release of BMP-2/7, RANKL, and tetracycline from FlexBone, an elastomeric osteoconductive bone substitute. J Orthop Res. 2009 Oct; 27(10):1306-11.
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Kaufman JD, Song J, Klapperich CM. Nanomechanical analysis of bone tissue engineering scaffolds. J Biomed Mater Res A. 2007 Jun 01; 81(3):611-23.
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Qiu QQ, Mendenhall HV, Garlick DS, Connor J. Evaluation of bone regeneration at critical-sized calvarial defect by DBM/AM composite. J Biomed Mater Res B Appl Biomater. 2007 May; 81(2):516-23.