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Robert Charles Brewster PhD

TitleAssociate Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentMicrobiology and Physiological Systems
AddressUniversity of Massachusetts Medical School
55 Lake Avenue North, AS5-1043
Worcester MA 01655
Phone774-455-3695
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentMicrobiology and Physiological Systems

    InstitutionUMMS - Graduate School of Biomedical Sciences
    DepartmentInterdisciplinary Graduate Program

    InstitutionUMMS - Programs, Centers and Institutes
    DepartmentSystems Biology


    Collapse Biography 
    Collapse education and training
    University of Massachusetts Amherst, Amherst, MA, United StatesBSPhysics
    University of California, Los Angeles, Los Angeles, CA, United StatesPHDPhysical Chemistry

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ali MZ, Parisutham V, Choubey S, Brewster RC. Inherent regulatory asymmetry emanating from network architecture in a prevalent autoregulatory motif. Elife. 2020 Aug 18; 9. PMID: 32808926.
      View in: PubMed
    2. Ali MZ, Choubey S, Das D, Brewster RC. Probing Mechanisms of Transcription Elongation Through Cell-to-Cell Variability of RNA Polymerase. Biophys J. 2020 Feb 12. PMID: 32101716.
      View in: PubMed
    3. Bulcha JT, Giese GE, Ali MZ, Lee YU, Walker MD, Holdorf AD, Yilmaz LS, Brewster RC, Walhout AJM. A Persistence Detector for Metabolic Network Rewiring in an Animal. Cell Rep. 2019 Jan 08; 26(2):460-468.e4. PMID: 30625328.
      View in: PubMed
    4. Landman J, Brewster RC, Weinert FM, Phillips R, Kegel WK. Self-consistent theory of transcriptional control in complex regulatory architectures. PLoS One. 2017; 12(7):e0179235. PMID: 28686609.
      View in: PubMed
    5. Das D, Dey S, Brewster RC, Choubey S. Effect of transcription factor resource sharing on gene expression noise. PLoS Comput Biol. 2017 Apr 17; 13(4):e1005491. PMID: 28414750.
      View in: PubMed
    6. Garcia HG, Brewster RC, Phillips R. Using synthetic biology to make cells tomorrow's test tubes. Integr Biol (Camb). 2016 Apr 18; 8(4):431-50. PMID: 26952708.
      View in: PubMed
    7. Lovely GA, Brewster RC, Schatz DG, Baltimore D, Phillips R. Single-molecule analysis of RAG-mediated V(D)J DNA cleavage. Proc Natl Acad Sci U S A. 2015 Apr 7; 112(14):E1715-23. PMID: 25831509.
      View in: PubMed
    8. Jones DL, Brewster RC, Phillips R. Promoter architecture dictates cell-to-cell variability in gene expression. Science. 2014 Dec 19; 346(6216):1533-6. PMID: 25525251.
      View in: PubMed
    9. Weinert FM, Brewster RC, Rydenfelt M, Phillips R, Kegel WK. Scaling of gene expression with transcription-factor fugacity. Phys Rev Lett. 2014 Dec 19; 113(25):258101. PMID: 25554908.
      View in: PubMed
    10. Brewster RC, Weinert FM, Garcia HG, Song D, Rydenfelt M, Phillips R. The transcription factor titration effect dictates level of gene expression. Cell. 2014 Mar 13; 156(6):1312-23. PMID: 24612990.
      View in: PubMed
    11. Palmieri B, Yamamoto T, Brewster RC, Safran SA. Line active molecules promote inhomogeneous structures in membranes: theory, simulations and experiments. Adv Colloid Interface Sci. 2014 Jun; 208:58-65. PMID: 24630340.
      View in: PubMed
    12. Brewster RC, Jones DL, Phillips R. Tuning promoter strength through RNA polymerase binding site design in Escherichia coli. PLoS Comput Biol. 2012; 8(12):e1002811. PMID: 23271961.
      View in: PubMed
    13. Jho YS, Brewster R, Safran SA, Pincus PA. Long-range interaction between heterogeneously charged membranes. Langmuir. 2011 Apr 19; 27(8):4439-46. PMID: 21410204.
      View in: PubMed
    14. Brewster R, Safran SA. Line active hybrid lipids determine domain size in phase separation of saturated and unsaturated lipids. Biophys J. 2010 Mar 17; 98(6):L21-3. PMID: 20303848.
      View in: PubMed
    15. Brewster R, Pincus PA, Safran SA. Hybrid lipids as a biological surface-active component. Biophys J. 2009 Aug 19; 97(4):1087-94. PMID: 19686656.
      View in: PubMed
    16. Brewster R, Grest GS, Levine AJ. Effects of cohesion on the surface angle and velocity profiles of granular material in a rotating drum. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Jan; 79(1 Pt 1):011305. PMID: 19257028.
      View in: PubMed
    17. Brewster R, Pincus PA, Safran SA. Self assembly modulated by interactions of two heterogeneously charged surfaces. Phys Rev Lett. 2008 Sep 19; 101(12):128101. PMID: 18851414.
      View in: PubMed
    18. Brewster R, Silbert LE, Grest GS, Levine AJ. Relationship between interparticle contact lifetimes and rheology in gravity-driven granular flows. Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Jun; 77(6 Pt 1):061302. PMID: 18643252.
      View in: PubMed
    19. Silbert LE, Grest GS, Brewster R, Levine AJ. Rheology and contact lifetimes in dense granular flows. Phys Rev Lett. 2007 Aug 10; 99(6):068002. PMID: 17930867.
      View in: PubMed
    20. Brewster R, Grest GS, Landry JW, Levine AJ. Plug flow and the breakdown of Bagnold scaling in cohesive granular flows. Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Dec; 72(6 Pt 1):061301. PMID: 16485940.
      View in: PubMed
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