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Robert Charles Brewster PhD

TitleAssociate Professor
InstitutionUMass Chan Medical School
DepartmentSystems Biology
AddressUMass Chan Medical School
55 Lake Avenue North AS5-1043
Worcester MA 01655
Phone774-455-3695
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMicrobiology

    InstitutionT.H. Chan School of Medicine
    DepartmentSystems Biology

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentBiophysical Chemical and Computational Biology

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentInterdisciplinary Graduate Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentPostbaccalaureate Research Education Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentSystems Computational and Quantitative Biology


    Collapse Biography 
    Collapse education and training
    University of Massachusetts Amherst, Amherst, MA, United StatesBSPhysics
    University of California, Los Angeles, Los Angeles, CA, United StatesPHDPhysical Chemistry

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ali MZ, Guharajan S, Parisutham V, Brewster RC. Regulatory properties of transcription factors with diverse mechanistic function. PLoS Comput Biol. 2024 Jun; 20(6):e1012194. PMID: 38857275.
      Citations:    
    2. Parisutham V, Chhabra S, Ali MZ, Brewster RC. Tunable transcription factor library for robust quantification of regulatory properties in Escherichia coli. Mol Syst Biol. 2022 06; 18(6):e10843. PMID: 35694815.
      Citations: 2     Fields:    Translation:Cells
    3. Ali MZ, Brewster RC. Controlling gene expression timing through gene regulatory architecture. PLoS Comput Biol. 2022 01; 18(1):e1009745. PMID: 35041641.
      Citations: 3     Fields:    Translation:Cells
    4. Guharajan S, Chhabra S, Parisutham V, Brewster RC. Quantifying the regulatory role of individual transcription factors in Escherichia coli. Cell Rep. 2021 11 09; 37(6):109952. PMID: 34758318.
      Citations: 1     Fields:    Translation:Cells
    5. Ali MZ, Parisutham V, Choubey S, Brewster RC. Inherent regulatory asymmetry emanating from network architecture in a prevalent autoregulatory motif. Elife. 2020 08 18; 9. PMID: 32808926.
      Citations: 6     Fields:    Translation:Cells
    6. Ali MZ, Choubey S, Das D, Brewster RC. Probing Mechanisms of Transcription Elongation Through Cell-to-Cell Variability of RNA Polymerase. Biophys J. 2020 04 07; 118(7):1769-1781. PMID: 32101716.
      Citations: 9     Fields:    Translation:Cells
    7. Bulcha JT, Giese GE, Ali MZ, Lee YU, Walker MD, Holdorf AD, Yilmaz LS, Brewster RC, Walhout AJM. A Persistence Detector for Metabolic Network Rewiring in an Animal. Cell Rep. 2019 01 08; 26(2):460-468.e4. PMID: 30625328.
      Citations: 23     Fields:    Translation:AnimalsCells
    8. Landman J, Brewster RC, Weinert FM, Phillips R, Kegel WK. Self-consistent theory of transcriptional control in complex regulatory architectures. PLoS One. 2017; 12(7):e0179235. PMID: 28686609.
      Citations: 6     Fields:    Translation:Cells
    9. Das D, Dey S, Brewster RC, Choubey S. Effect of transcription factor resource sharing on gene expression noise. PLoS Comput Biol. 2017 04; 13(4):e1005491. PMID: 28414750.
      Citations: 15     Fields:    Translation:Cells
    10. Jones DL, Brewster RC, Phillips R. Promoter architecture dictates cell-to-cell variability in gene expression. Science. 2014 Dec 19; 346(6216):1533-6. PMID: 25525251.
      Citations: 90     Fields:    Translation:Cells
    11. Weinert FM, Brewster RC, Rydenfelt M, Phillips R, Kegel WK. Scaling of gene expression with transcription-factor fugacity. Phys Rev Lett. 2014 Dec 19; 113(25):258101. PMID: 25554908.
      Citations: 22     Fields:    
    12. Brewster RC, Weinert FM, Garcia HG, Song D, Rydenfelt M, Phillips R. The transcription factor titration effect dictates level of gene expression. Cell. 2014 Mar 13; 156(6):1312-1323. PMID: 24612990.
      Citations: 114     Fields:    Translation:Cells
    13. Palmieri B, Yamamoto T, Brewster RC, Safran SA. Line active molecules promote inhomogeneous structures in membranes: theory, simulations and experiments. Adv Colloid Interface Sci. 2014 Jun; 208:58-65. PMID: 24630340.
      Citations: 15     Fields:    
    14. Brewster RC, Jones DL, Phillips R. Tuning promoter strength through RNA polymerase binding site design in Escherichia coli. PLoS Comput Biol. 2012; 8(12):e1002811. PMID: 23271961.
      Citations: 78     Fields:    Translation:Cells
    15. Jho YS, Brewster R, Safran SA, Pincus PA. Long-range interaction between heterogeneously charged membranes. Langmuir. 2011 Apr 19; 27(8):4439-46. PMID: 21410204.
      Citations: 5     Fields:    
    16. Brewster R, Safran SA. Line active hybrid lipids determine domain size in phase separation of saturated and unsaturated lipids. Biophys J. 2010 Mar 17; 98(6):L21-3. PMID: 20303848.
      Citations: 30     Fields:    Translation:Cells
    17. Brewster R, Pincus PA, Safran SA. Hybrid lipids as a biological surface-active component. Biophys J. 2009 Aug 19; 97(4):1087-94. PMID: 19686656.
      Citations: 34     Fields:    Translation:Cells
    18. Brewster R, Grest GS, Levine AJ. Effects of cohesion on the surface angle and velocity profiles of granular material in a rotating drum. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Jan; 79(1 Pt 1):011305. PMID: 19257028.
      Citations: 1     Fields:    
    19. Brewster R, Pincus PA, Safran SA. Self assembly modulated by interactions of two heterogeneously charged surfaces. Phys Rev Lett. 2008 Sep 19; 101(12):128101. PMID: 18851414.
      Citations: 1     Fields:    
    20. Brewster R, Silbert LE, Grest GS, Levine AJ. Relationship between interparticle contact lifetimes and rheology in gravity-driven granular flows. Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Jun; 77(6 Pt 1):061302. PMID: 18643252.
      Citations:    Fields:    
    21. Silbert LE, Grest GS, Brewster R, Levine AJ. Rheology and contact lifetimes in dense granular flows. Phys Rev Lett. 2007 Aug 10; 99(6):068002. PMID: 17930867.
      Citations:    Fields:    
    22. Brewster R, Grest GS, Landry JW, Levine AJ. Plug flow and the breakdown of Bagnold scaling in cohesive granular flows. Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Dec; 72(6 Pt 1):061301. PMID: 16485940.
      Citations: 2     Fields:    
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