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Cynthia K Sites MD

InstitutionUMass Chan – Baystate Regional Campus
DepartmentObstetrics and Gynecology at UMass Chan - Baystate
AddressBaystate Health Regional Campus
759 Chestnut Street
Springfield MA 01199
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    Ohio State University Columbus, Columbus, OH, United StatesBSZoology
    Ohio State University Columbus, Columbus, OH, United StatesMD

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Oluwayiose OA, Houle E, Whitcomb BW, Suvorov A, Rahil T, Sites CK, Krawetz SA, Visconti PE, Pilsner JR. Non-coding RNAs from seminal plasma extracellular vesicles and success of live birth among couples undergoing fertility treatment. Front Cell Dev Biol. 2023; 11:1174211. PMID: 37427387.
    2. Houle E, Li Y, Schroder M, McRitchie SL, Rahil T, Sites CK, Jenkins Sumner S, Pilsner JR. Exploring the internal exposome of seminal plasma with semen quality and live birth: A Pilot Study. Syst Biol Reprod Med. 2023 Aug; 69(4):296-309. PMID: 37098216.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    3. Oluwayiose OA, Houle E, Whitcomb BW, Suvorov A, Rahil T, Sites CK, Krawetz SA, Visconti PE, Pilsner JR. Urinary phthalate metabolites and small non-coding RNAs from seminal plasma extracellular vesicles among men undergoing infertility treatment. Environ Pollut. 2023 Jul 15; 329:121529. PMID: 37003585.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    4. Oluwayiose OA, Houle E, Whitcomb BW, Suvorov A, Rahil T, Sites CK, Krawetz SA, Visconti P, Pilsner JR. Altered non-coding RNA profiles of seminal plasma extracellular vesicles of men with poor semen quality undergoing in vitro fertilization treatment. Andrology. 2023 05; 11(4):677-686. PMID: 36111950.
      Citations: 4     Fields:    Translation:HumansCells
    5. Sites CK, Bachilova S, Gopal D, Cabral HJ, Coddington CC, Stern JE. Embryo biopsy and maternal and neonatal outcomes following cryopreserved-thawed single embryo transfer. Am J Obstet Gynecol. 2021 09; 225(3):285.e1-285.e7. PMID: 33894152.
      Citations: 6     Fields:    Translation:Humans
    6. Oluwayiose OA, Wu H, Saddiki H, Whitcomb BW, Balzer LB, Brandon N, Suvorov A, Tayyab R, Sites CK, Hill L, Marcho C, Pilsner JR. Sperm DNA methylation mediates the association of male age on reproductive outcomes among couples undergoing infertility treatment. Sci Rep. 2021 02 05; 11(1):3216. PMID: 33547328.
      Citations: 17     Fields:    Translation:HumansCells
    7. Oluwayiose OA, Josyula S, Houle E, Marcho C, Rahil T, Sites CK, Pilsner JR. Association between sperm mitochondarial DNA copy number and nuclear DNA methylation. Epigenomics. 2020 12; 12(24):2141-2153. PMID: 33320694.
      Citations: 1     Fields:    Translation:HumansCells
    8. Sites CK, Wilson D, Bernson D, Boulet S, Zhang Y. Number of embryos transferred and diagnosis of preeclampsia. Reprod Biol Endocrinol. 2020 Jul 11; 18(1):68. PMID: 32653045.
      Citations:    Fields:    Translation:Humans
    9. Wu H, Whitcomb BW, Huffman A, Brandon N, Labrie S, Tougias E, Lynch K, Rahil T, Sites CK, Pilsner JR. Associations of sperm mitochondrial DNA copy number and deletion rate with fertilization and embryo development in a clinical setting. Hum Reprod. 2019 Jan 01; 34(1):163-170. PMID: 30428043.
      Citations: 13     Fields:    Translation:HumansCells
    10. Wu H, Huffman AM, Whitcomb BW, Josyula S, Labrie S, Tougias E, Rahil T, Sites CK, Pilsner JR. Sperm mitochondrial DNA measures and semen parameters among men undergoing fertility treatment. Reprod Biomed Online. 2019 Jan; 38(1):66-75. PMID: 30502072.
      Citations: 8     Fields:    Translation:HumansCells
    11. Huffman AM, Wu H, Rosati A, Rahil T, Sites CK, Whitcomb BW, Richard Pilsner J. Associations of urinary phthalate metabolites and lipid peroxidation with sperm mitochondrial DNA copy number and deletions. Environ Res. 2018 05; 163:10-15. PMID: 29421168.
      Citations: 10     Fields:    Translation:HumansCells
    12. Wu H, Estill MS, Shershebnev A, Suvorov A, Krawetz SA, Whitcomb BW, Dinnie H, Rahil T, Sites CK, Pilsner JR. Preconception urinary phthalate concentrations and sperm DNA methylation profiles among men undergoing IVF treatment: a cross-sectional study. Hum Reprod. 2017 11 01; 32(11):2159-2169. PMID: 29024969.
      Citations: 41     Fields:    Translation:HumansCells
    13. Sites CK, Wilson D, Barsky M, Bernson D, Bernstein IM, Boulet S, Zhang Y. Embryo cryopreservation and preeclampsia risk. Fertil Steril. 2017 11; 108(5):784-790. PMID: 28974308.
      Citations: 33     Fields:    Translation:Humans
    14. Wu H, Ashcraft L, Whitcomb BW, Rahil T, Tougias E, Sites CK, Pilsner JR. Parental contributions to early embryo development: influences of urinary phthalate and phthalate alternatives among couples undergoing IVF treatment. Hum Reprod. 2017 01; 32(1):65-75. PMID: 27927842.
      Citations: 29     Fields:    Translation:HumansPHPublic Health
    15. Wu H, Olmsted A, Cantonwine DE, Shahsavari S, Rahil T, Sites C, Pilsner JR. Urinary phthalate and phthalate alternative metabolites and isoprostane among couples undergoing fertility treatment. Environ Res. 2017 Feb; 153:1-7. PMID: 27875712.
      Citations: 13     Fields:    Translation:HumansPHPublic Health
    16. Barsky M, St Marie P, Rahil T, Markenson GR, Sites CK. Are perinatal outcomes affected by blastocyst vitrification and warming? Am J Obstet Gynecol. 2016 Nov; 215(5):603.e1-603.e5. PMID: 27287684.
      Citations: 17     Fields:    Translation:Humans
    17. Merkin SS, Phy JL, Sites CK, Yang D. Environmental determinants of?polycystic ovary syndrome. Fertil Steril. 2016 07; 106(1):16-24. PMID: 27240194.
      Citations: 43     Fields:    Translation:Humans
    18. Sites CK, St Marie P, Rahil T. Implantation of fresh and thawed-warmed embryos in single embryo transfer cycles: interpreting the initial beta-HCG. Reprod Biomed Online. 2015 Mar; 30(3):319-21. PMID: 25592975.
      Citations: 3     Fields:    Translation:Humans
    19. Dumas JA, Albert KM, Naylor MR, Sites CK, Benkelfat C, Newhouse PA. The effects of age and estrogen on stress responsivity in older women. Am J Geriatr Psychiatry. 2012 Sep; 20(9):734-43. PMID: 22832417.
      Citations: 12     Fields:    Translation:Humans
    20. McKnight KK, Wellons MF, Sites CK, Roth DL, Szychowski JM, Halanych JH, Cushman M, Safford MM. Racial and regional differences in age at menopause in the United States: findings from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study. Am J Obstet Gynecol. 2011 Oct; 205(4):353.e1-8. PMID: 21663888.
      Citations: 23     Fields:    Translation:Humans
    21. Steiner AZ, Fritz M, Sites CK, Coutifaris C, Carr BR, Barnhart K. Resident experience on reproductive endocrinology and infertility rotations and perceived knowledge. Obstet Gynecol. 2011 Feb; 117(2 Pt 1):324-330. PMID: 21252746.
      Citations: 6     Fields:    Translation:Humans
    22. Newhouse PA, Dumas J, Wilkins H, Coderre E, Sites CK, Naylor M, Benkelfat C, Young SN. Estrogen treatment impairs cognitive performance after psychosocial stress and monoamine depletion in postmenopausal women. Menopause. 2010 Jul; 17(4):860-73. PMID: 20616673.
      Citations: 22     Fields:    Translation:Humans
    23. Christie DR, Grant J, Darnell BE, Chapman VR, Gastaldelli A, Sites CK. Metabolic effects of soy supplementation in postmenopausal Caucasian and African American women: a randomized, placebo-controlled trial. Am J Obstet Gynecol. 2010 Aug; 203(2):153.e1-9. PMID: 20435291.
      Citations: 14     Fields:    Translation:Humans
    24. Wellons MF, Lewis CE, Schwartz SM, Gunderson EP, Schreiner PJ, Sternfeld B, Richman J, Sites CK, Siscovick DS. Racial differences in self-reported infertility and risk factors for infertility in a cohort of black and white women: the CARDIA Women's Study. Fertil Steril. 2008 Nov; 90(5):1640-8. PMID: 18321499.
      Citations: 30     Fields:    Translation:Humans
    25. Sites CK. Bioidentical hormones for menopausal therapy. Womens Health (Lond). 2008 Mar; 4(2):163-71. PMID: 19072518.
      Citations: 5     Fields:    Translation:Humans
    26. Dumas J, Hancur-Bucci C, Naylor M, Sites C, Newhouse P. Estradiol interacts with the cholinergic system to affect verbal memory in postmenopausal women: evidence for the critical period hypothesis. Horm Behav. 2008 Jan; 53(1):159-69. PMID: 17964576.
      Citations: 58     Fields:    Translation:Humans
    27. Newhouse PA, Dumas J, Hancur-Bucci C, Naylor M, Sites CK, Benkelfat C, Young SN. Estrogen administration negatively alters mood following monoaminergic depletion and psychosocial stress in postmenopausal women. Neuropsychopharmacology. 2008 Jun; 33(7):1514-27. PMID: 17700646.
      Citations: 21     Fields:    Translation:Humans
    28. Cooper BC, Sites CK, Casson PR, Toth MJ. Ovarian suppression with a gonadotropin-releasing hormone agonist does not alter insulin-stimulated glucose disposal. Fertil Steril. 2007 May; 87(5):1131-8. PMID: 17478172.
      Citations: 8     Fields:    Translation:Humans
    29. Sites CK, Cooper BC, Toth MJ, Gastaldelli A, Arabshahi A, Barnes S. Effect of a daily supplement of soy protein on body composition and insulin secretion in postmenopausal women. Fertil Steril. 2007 Dec; 88(6):1609-17. PMID: 17412329.
      Citations: 21     Fields:    Translation:Humans
    30. Cooper BC, Burger NZ, Toth MJ, Cushman M, Sites CK. Insulin resistance with hormone replacement therapy: associations with markers of inflammation and adiposity. Am J Obstet Gynecol. 2007 Feb; 196(2):123.e1-7. PMID: 17306648.
      Citations: 7     Fields:    Translation:Humans
    31. Cooper BC, Sites CK, Fairhurst PA, Toth MJ. Evidence against a role for ovarian hormones in the regulation of blood flow. Fertil Steril. 2006 Aug; 86(2):440-7. PMID: 16764868.
      Citations: 7     Fields:    Translation:Humans
    32. Toth MJ, Sites CK, Matthews DE. Role of ovarian hormones in the regulation of protein metabolism in women: effects of menopausal status and hormone replacement therapy. Am J Physiol Endocrinol Metab. 2006 Sep; 291(3):E639-46. PMID: 16684855.
      Citations: 2     Fields:    Translation:Humans
    33. Toth MJ, Sites CK, Matthews DE, Casson PR. Ovarian suppression with gonadotropin-releasing hormone agonist reduces whole body protein turnover in women. Am J Physiol Endocrinol Metab. 2006 Sep; 291(3):E483-90. PMID: 16621894.
      Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
    34. Dumas J, Hancur-Bucci C, Naylor M, Sites C, Newhouse P. Estrogen treatment effects on anticholinergic-induced cognitive dysfunction in normal postmenopausal women. Neuropsychopharmacology. 2006 Sep; 31(9):2065-78. PMID: 16482084.
      Citations: 41     Fields:    Translation:Humans
    35. Goodrow GJ, L'Hommedieu GD, Gannon B, Sites CK. Predictors of worsening insulin sensitivity in postmenopausal women. Am J Obstet Gynecol. 2006 Feb; 194(2):355-61. PMID: 16458629.
      Citations: 4     Fields:    Translation:Humans
    36. Sites CK, L'Hommedieu GD, Toth MJ, Brochu M, Cooper BC, Fairhurst PA. The effect of hormone replacement therapy on body composition, body fat distribution, and insulin sensitivity in menopausal women: a randomized, double-blind, placebo-controlled trial. J Clin Endocrinol Metab. 2005 May; 90(5):2701-7. PMID: 15687338.
      Citations: 36     Fields:    Translation:HumansCTClinical Trials
    37. Goldstein J, Sites CK, Toth MJ. Progesterone stimulates cardiac muscle protein synthesis via receptor-dependent pathway. Fertil Steril. 2004 Aug; 82(2):430-6. PMID: 15302294.
      Citations: 17     Fields:    Translation:Animals
    38. Toth MJ, Sites CK, Poehlman ET, Tchernof A. Effect of menopausal status on lipolysis: comparison of plasma glycerol levels in middle-aged, premenopausal and early, postmenopausal women. Metabolism. 2002 Mar; 51(3):322-6. PMID: 11887168.
      Citations: 2     Fields:    Translation:HumansCells
    39. Goldstein JS, Sites CK. Selective modulation of sex steroids. Ageing Res Rev. 2002 Feb; 1(1):17-28. PMID: 12039446.
      Citations: 5     Fields:    Translation:Humans
    40. Sites CK, Toth MJ, Cushman M, L'Hommedieu GD, Tchernof A, Tracy RP, Poehlman ET. Menopause-related differences in inflammation markers and their relationship to body fat distribution and insulin-stimulated glucose disposal. Fertil Steril. 2002 Jan; 77(1):128-35. PMID: 11779602.
      Citations: 53     Fields:    Translation:Humans
    41. Sites CK, L'Hommedieu GD, Brochu M, Poehlman ET. Previous exposure to hormone replacement therapy and confounders in metabolic studies. Menopause. 2001 Jul-Aug; 8(4):281-5. PMID: 11449086.
      Citations:    Fields:    Translation:Humans
    42. Sites CK, Brochu M, Tchernof A, Poehlman ET. Relationship between hormone replacement therapy use with body fat distribution and insulin sensitivity in obese postmenopausal women. Metabolism. 2001 Jul; 50(7):835-40. PMID: 11436191.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    43. DeNino WF, Tchernof A, Dionne IJ, Toth MJ, Ades PA, Sites CK, Poehlman ET. Contribution of abdominal adiposity to age-related differences in insulin sensitivity and plasma lipids in healthy nonobese women. Diabetes Care. 2001 May; 24(5):925-32. PMID: 11347756.
      Citations: 52     Fields:    Translation:Humans
    44. Brochu M, Tchernof A, Dionne IJ, Sites CK, Eltabbakh GH, Sims EA, Poehlman ET. What are the physical characteristics associated with a normal metabolic profile despite a high level of obesity in postmenopausal women? J Clin Endocrinol Metab. 2001 Mar; 86(3):1020-5. PMID: 11238480.
      Citations: 169     Fields:    Translation:Humans
    45. Toth MJ, Sites CK, Eltabbakh GH, Poehlman ET. Effect of menopausal status on insulin-stimulated glucose disposal: comparison of middle-aged premenopausal and early postmenopausal women. Diabetes Care. 2000 Jun; 23(6):801-6. PMID: 10841000.
      Citations: 16     Fields:    Translation:Humans
    46. Toth MJ, Tchernof A, Sites CK, Poehlman ET. Menopause-related changes in body fat distribution. Ann N Y Acad Sci. 2000 May; 904:502-6. PMID: 10865795.
      Citations: 67     Fields:    Translation:Humans
    47. Shamonki MI, Ziegler WF, Badger GJ, Sites CK. Prediction of endometrial ablation success according to perioperative findings. Am J Obstet Gynecol. 2000 May; 182(5):1005-7. PMID: 10819809.
      Citations: 4     Fields:    Translation:Humans
    48. Toth MJ, Tchernof A, Sites CK, Poehlman ET. Effect of menopausal status on body composition and abdominal fat distribution. Int J Obes Relat Metab Disord. 2000 Feb; 24(2):226-31. PMID: 10702775.
      Citations: 127     Fields:    Translation:Humans
    49. Sites CK, Calles-Escand?n J, Brochu M, Butterfield M, Ashikaga T, Poehlman ET. Relation of regional fat distribution to insulin sensitivity in postmenopausal women. Fertil Steril. 2000 Jan; 73(1):61-5. PMID: 10632413.
      Citations: 19     Fields:    Translation:Humans
    50. Porter MB, Brumsted JR, Sites CK. Effect of prolactin on follicle-stimulating hormone receptor binding and progesterone production in cultured porcine granulosa cells. Fertil Steril. 2000 Jan; 73(1):99-105. PMID: 10632421.
      Citations: 2     Fields:    Translation:AnimalsCells
    51. Sites CK, Tischler MD, Rosen CJ, O'Connell M, Niggel J, Ashikaga T. Effect of short-term medroxyprogesterone acetate on left ventricular mass: role of insulin-like growth factor-1. Metabolism. 1999 Oct; 48(10):1328-31. PMID: 10535399.
      Citations:    Fields:    Translation:Humans
    52. Toth MJ, Sites CK, Poehlman ET. Hormonal and physiological correlates of energy expenditure and substrate oxidation in middle-aged, premenopausal women. J Clin Endocrinol Metab. 1999 Aug; 84(8):2771-5. PMID: 10443677.
      Citations: 1     Fields:    Translation:HumansCells
    53. Sites CK, Tischler MD, Blackman JA, Niggel J, Fairbank JT, O'Connell M, Ashikaga T. Effect of short-term hormone replacement therapy on left ventricular mass and contractile function. Fertil Steril. 1999 Jan; 71(1):137-43. PMID: 9935130.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    54. Storment JM, Kaiser JR, Sites CK. Transvaginal ultrasonographic diagnosis of uterine septa. J Reprod Med. 1998 Sep; 43(9):823-6. PMID: 9777623.
      Citations:    Fields:    Translation:Humans
    55. Sites CK. Hormone replacement therapy: cardiovascular benefits for aging women. Coron Artery Dis. 1998; 9(12):789-93. PMID: 9894922.
      Citations:    Fields:    Translation:Humans
    56. Tchernof A, Calles-Escandon J, Sites CK, Poehlman ET. Menopause, central body fatness, and insulin resistance: effects of hormone-replacement therapy. Coron Artery Dis. 1998; 9(8):503-11. PMID: 9847982.
      Citations: 42     Fields:    Translation:HumansAnimals
    57. Sites CK, Jensen BA, Glock JL, Blackman JA, Badger GJ, Johnson JV, Brumsted JR. Transvaginal ultrasonographic assessment of Hyskon or lactated Ringer's solution instillation after laparoscopy: randomized, controlled study. J Ultrasound Med. 1997 Mar; 16(3):195-9. PMID: 9166816.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    58. Viscomi CM, Hill K, Johnson J, Sites C. Spinal anesthesia versus intravenous sedation for transvaginal oocyte retrieval: reproductive outcome, side-effects and recovery profiles. Int J Obstet Anesth. 1997 Jan; 6(1):49-51. PMID: 15321311.
      Citations: 2     Fields:    
    59. Sites CK, Taylor EH, Lewis SJ, Brumsted JR. Development of a sensitive porcine granulosa cell bioassay for follicle-stimulating hormone (FSH). J Assist Reprod Genet. 1996 Jul; 13(6):505-10. PMID: 8835681.
      Citations:    Fields:    Translation:AnimalsCells
    60. Sites CK, Kessel B, LaBarbera AR. Adhesion proteins increase cellular attachment, follicle-stimulating hormone receptors, and progesterone production in cultured porcine granulosa cells. Proc Soc Exp Biol Med. 1996 May; 212(1):78-83. PMID: 8618955.
      Citations: 12     Fields:    Translation:AnimalsCells
    61. Sites CK. Treatment of ectopic pregnancy with single-dose methotrexate in a patient with an intrauterine device. A case report. J Reprod Med. 1995 Nov; 40(11):800-2. PMID: 8592317.
      Citations:    Fields:    Translation:Humans
    62. Sites CK, Sherer DM, Gandell DL, Woods JR. Extensive vulvar and vaginal varicella necessitating abdominal delivery. Am J Obstet Gynecol. 1990 Nov; 163(5 Pt 1):1630-1. PMID: 2240116.
      Citations:    Fields:    Translation:Humans
    63. Schmidt GE, Sites C, Mansour R, Friedman CI, Kim MH. Embryo toxicity of clomiphene citrate on mouse embryos fertilized in vitro and in vivo. Am J Obstet Gynecol. 1985 Nov 15; 153(6):679-84. PMID: 4061538.
      Citations: 2     Fields:    Translation:AnimalsCells
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