Autoantigens

"Autoantigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Endogenous tissue constituents that have the ability to interact with AUTOANTIBODIES and cause an immune response.

Descriptor ID	D001324
MeSH Number(s)	D23.050.422
Concept/Terms	Autoantigens Autoantigens Autologous Antigens Antigens, Autologous Self-Antigens Self Antigens

Below are MeSH descriptors whose meaning is more general than "Autoantigens".

Chemicals and Drugs [D]
Biological Factors [D23]
Antigens [D23.050]
Autoantigens [D23.050.422]

Below are MeSH descriptors whose meaning is related to "Autoantigens".

Below are MeSH descriptors whose meaning is more specific than "Autoantigens".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Autoantigens" by people in this website by year, and whether "Autoantigens" was a major or minor topic of these publications.

Bar chart showing 103 publications over 28 distinct years, with a maximum of 8 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1999	0	2	2
2001	1	2	3
2002	2	3	5
2003	3	2	5
2004	2	1	3
2005	4	0	4
2006	3	1	4
2007	5	1	6
2008	3	1	4
2009	3	0	3
2010	3	3	6
2011	4	3	7
2012	1	0	1
2013	3	3	6
2014	3	2	5
2015	2	2	4
2016	3	5	8
2017	0	3	3
2018	2	3	5
2019	2	2	4
2020	1	3	4
2021	0	1	1
2022	0	1	1
2023	0	2	2
2024	0	2	2
2025	1	1	2
2026	0	2	2

Below are the most recent publications written about "Autoantigens" by people in Profiles.

Funsten M, de Pooter R, Varanasi V, Burrows M, Block K, Kuznetsov A, Serreze D, Huang H, Chervonsky A. B cells enable autoreactive T cells to avoid suppression. Proc Natl Acad Sci U S A. 2026 Apr 14; 123(15):e2536291123.

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Amdare N, Ali R, Manganaro A, Baker JC, Antal Z, Smith C, Santamaria P, Kent SC, DiLorenzo TP. Islet-derived T cells from both mice and humans recognize conserved insulin A-chain peptides presented by HLA-C*03:04. J Immunol. 2026 02 09; 215(2).

View in: PubMed
Nanaware PP, Calvo-Calle JM, Redick SD, Tarpley MW, Cruz J, Clement CC, Manganaro A, Velarde de la Cruz EE, Muneeruddin K, Faulkner M, Wang JP, Shaffer SA, Harlan DM, Santambrogio L, Kent SC, Stern LJ. The antigen presentation landscape of cytokine-stressed human pancreatic islets. Cell Rep. 2025 Aug 26; 44(8):115927.

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Guyer P, Seminova K, Lugar M, Manganaro A, Velarde de la Cruz EE, Hartley R, Smithmyer ME, Speake C, Bonifacio E, Kent SC, James EA. T cell and autoantibody recognition of nucleus-associated islet autoantigens in individuals with type 1 diabetes. Diabetologia. 2025 Aug; 68(8):1721-1734.

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Amdare NP, Shultz LD, Greiner DL, DiLorenzo TP. Human insulin as both antigen and protector in type 1 diabetes. Eur J Immunol. 2024 Sep; 54(9):e2350949.

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Yin R, Melton S, Huseby ES, Kardar M, Chakraborty AK. How persistent infection overcomes peripheral tolerance mechanisms to cause T cell-mediated autoimmune disease. Proc Natl Acad Sci U S A. 2024 Mar 12; 121(11):e2318599121.

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Chen DP, Aiello CP, McCoy D, Stamey T, Yang J, Hogan SL, Hu Y, Derebail VK, Wu EY, Jennette JC, Falk RJ, Ciavatta DJ. PRTN3 variant correlates with increased autoantigen levels and relapse risk in PR3-ANCA versus MPO-ANCA disease. JCI Insight. 2023 02 22; 8(4).

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Abboud G, Choi SC, Zhang X, Park YP, Kanda N, Zeumer-Spataro L, Terrell M, Teng X, N?ndel K, Shlomchik MJ, Morel L. Glucose Requirement of Antigen-Specific Autoreactive B Cells and CD4+ T Cells. J Immunol. 2023 02 15; 210(4):377-388.

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Chen DP, McInnis EA, Wu EY, Stember KG, Hogan SL, Hu Y, Henderson CD, Blazek LN, Mallal S, Karosiene E, Peters B, Sidney J, James EA, Kwok WW, Jennette JC, Ciavatta DJ, Falk RJ, Free ME. Immunological Interaction of HLA-DPB1 and Proteinase 3 in ANCA Vasculitis is Associated with Clinical Disease Activity. J Am Soc Nephrol. 2022 08; 33(8):1517-1527.

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Ryan GE, Harris JE, Richmond JM. Resident Memory T Cells in Autoimmune Skin Diseases. Front Immunol. 2021; 12:652191.

View in: PubMed

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