A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Descriptor ID	D008180
MeSH Number(s)	C17.300.480 C20.111.590
Concept/Terms	Lupus Erythematosus, Systemic Lupus Erythematosus, Systemic Systemic Lupus Erythematosus Lupus Erythematosus Disseminatus Libman-Sacks Disease Libman-Sacks Disease Disease, Libman-Sacks Libman Sacks Disease

Below are MeSH descriptors whose meaning is more general than "Lupus Erythematosus, Systemic".

Below are MeSH descriptors whose meaning is related to "Lupus Erythematosus, Systemic".

Below are MeSH descriptors whose meaning is more specific than "Lupus Erythematosus, Systemic".