"Puromycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
| Descriptor ID |
D011691
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| MeSH Number(s) |
D02.241.223.200.380 D03.633.100.759.590.138.711 D09.408.051.788 D13.570.583.138.711
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Puromycin".
Below are MeSH descriptors whose meaning is more specific than "Puromycin".
This graph shows the total number of publications written about "Puromycin" by people in this website by year, and whether "Puromycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Puromycin" by people in Profiles.
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Messina MS, Torrente L, Pezacki AT, Humpel HI, Li EL, Miller SG, Verdejo-Torres O, Padilla-Benavides T, Brady DC, Killilea DW, Killilea AN, Ralle M, Ward NP, Ohata J, DeNicola GM, Chang CJ. A histochemical approach to activity-based copper sensing reveals cuproplasia-dependent vulnerabilities in cancer. Proc Natl Acad Sci U S A. 2025 Jan 21; 122(3):e2412816122.
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Pederson T. The persistent plausibility of protein synthesis in the nucleus: process, palimpsest or pitfall? Curr Opin Cell Biol. 2013 Aug; 25(4):520-1.
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Munro JB, Altman RB, O'Connor N, Blanchard SC. Identification of two distinct hybrid state intermediates on the ribosome. Mol Cell. 2007 Feb 23; 25(4):505-17.
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Saric T, Beninga J, Graef CI, Akopian TN, Rock KL, Goldberg AL. Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase. J Biol Chem. 2001 Sep 28; 276(39):36474-81.
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Zambetti G, Wilming L, Fey EG, Penman S, Stein J, Stein G. Differential association of membrane-bound and non-membrane-bound polysomes with the cytoskeleton. Exp Cell Res. 1990 Dec; 191(2):246-55.
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Zambetti G, Fey EG, Penman S, Stein J, Stein G. Multiple types of mRNA-cytoskeleton interactions. J Cell Biochem. 1990 Nov; 44(3):177-87.
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Morrison TG, McQuain C. Assembly of viral membranes. I. Association of vesicular stomatitis virus membrane proteins and membranes in a cell-free system. J Virol. 1977 Feb; 21(2):451-8.
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Perlman S, Abelson HT, Penman S. Mitochondrial protein synthesis: RNA with the properties of Eukaryotic messenger RNA. Proc Natl Acad Sci U S A. 1973 Feb; 70(2):350-3.