Scleroderma, Localized

"Scleroderma, Localized" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules.

Descriptor ID	D012594
MeSH Number(s)	C17.300.787 C17.800.767
Concept/Terms	Scleroderma, Localized Scleroderma, Localized Localized Scleroderma Sclerodermas, Localized Scleroderma, Circumscribed Circumscribed Scleroderma Dermatosclerosis Dermatosclerosis Morphea Morphea Morpheas Scleroderma, Linear Scleroderma, Linear Linear Scleroderma Frontal Linear Scleroderma en Coup de Sabre

Below are MeSH descriptors whose meaning is more general than "Scleroderma, Localized".

Diseases [C]
Skin and Connective Tissue Diseases [C17]
Connective Tissue Diseases [C17.300]
Scleroderma, Localized [C17.300.787]
Skin Diseases [C17.800]
Scleroderma, Localized [C17.800.767]

Below are MeSH descriptors whose meaning is related to "Scleroderma, Localized".

Below are MeSH descriptors whose meaning is more specific than "Scleroderma, Localized".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Scleroderma, Localized" by people in this website by year, and whether "Scleroderma, Localized" was a major or minor topic of these publications.

Bar chart showing 7 publications over 5 distinct years, with a maximum of 2 publications in 2017 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Total
2017	2	2
2020	1	1
2021	1	1
2023	2	2
2025	1	1

Below are the most recent publications written about "Scleroderma, Localized" by people in Profiles.

Egeli BH, Dallas J, Reusch DB, Shaw KS, Gellis S, Sundel R, Son MB, Vleugels RA, Dedeoglu F. Juvenile localized scleroderma: a large retrospective cohort study from a tertiary care center. Pediatr Rheumatol Online J. 2025 Jun 06; 23(1):63.

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Shaw KS, Nguyen TT, Rajeh A, Cohen SM, Semenov YR, Reusch DB, Dedeoglu F, Vleugels RA, Ganske IM. Use of 3-Dimensional Stereophotogrammetry to Detect Disease Progression in Craniofacial Morphea. JAMA Dermatol. 2023 11 01; 159(11):1232-1239.

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Richmond JM, Patel D, Watanabe T, Chen HW, Martyanov V, Werner G, Garg M, Haddadi NS, Refat MA, Mahmoud BH, Wong LD, Dresser K, Deng A, Zhu JL, McAlpine W, Hosler GA, Feghali-Bostwick CA, Whitfield ML, Harris JE, Torok KS, Jacobe HT. CXCL9 Links Skin Inflammation and Fibrosis through CXCR3-Dependent Upregulation of Col1a1 in Fibroblasts. J Invest Dermatol. 2023 07; 143(7):1138-1146.e12.

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Wenzel D, Haddadi NS, Afshari K, Richmond JM, Rashighi M. Upcoming treatments for morphea. Immun Inflamm Dis. 2021 12; 9(4):1101-1145.

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Damsky W, Patel D, Garelli CJ, Garg M, Wang A, Dresser K, Deng A, Harris JE, Richmond J, King B. Jak Inhibition Prevents Bleomycin-Induced Fibrosis in Mice and Is Effective in Patients with Morphea. J Invest Dermatol. 2020 07; 140(7):1446-1449.e4.

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Loyal J, Norris II, Lester EB, Pierson JC. Superficial morphea: case report, look-alikes, pathogenesis, and treatment. Dermatol Online J. 2017 May 15; 23(5).

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Pham AK, Srivastava B, Deng A. Pregnancy-associated morphea: a case report and literature review. Dermatol Online J. 2017 Jan 15; 23(1).

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Dunn RM, Fudem GM, Walton RL, Anderson FA, Malhotra R. Free flap valvular transplantation for refractory venous ulceration. J Vasc Surg. 1994 Mar; 19(3):525-31.

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