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Last Name

Michela Frascoli PhD

InstitutionUniversity of Massachusetts Medical School
AddressUniversity of Massachusetts Medical School
55 Lake Avenue North
Worcester MA 01655
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    Other Positions
    InstitutionUMMS - School of Medicine

    Collapse Biography 
    Collapse education and training
    University of Insubria, Varese, VA, ItalyBSBiology
    University of Insubria, Varese, VA, ItalyMSMolecular & Cellular Biology
    Institute for Research in Biomedicine, Bellinzona, , SwitzerlandPHDBiomedicine
    University of California San Francisco, San FranciscoPostdocImmunology

    Collapse Research 
    Collapse research activities and funding
         (Michela Frascoli)Jul 1, 2018 - Jun 30, 2020
    Charles H. Hood Foundation Child Health Research Awards Program
    Role: PI

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Witt RG, Blair L, Frascoli M, Rosen MJ, Nguyen QH, Bercovici S, Zompi S, Romero R, Mackenzie TC. Detection of microbial cell-free DNA in maternal and umbilical cord plasma in patients with chorioamnionitis using next generation sequencing. PLoS One. 2020; 15(4):e0231239. PMID: 32294121.
      View in: PubMed
    2. Spidale NA, Malhotra N, Frascoli M, Sylvia K, Miu B, Freeman C, Stadinski BD, Huseby E, Kang J. Neonatal-derived IL-17 producing dermal ?d T cells are required to prevent spontaneous atopic dermatitis. Elife. 2020 Feb 17; 9. PMID: 32065580.
      View in: PubMed
    3. Spidale NA, Frascoli M, Kang J. ?dTCR-independent origin of neonatal ?d T cells prewired for IL-17 production. Curr Opin Immunol. 2019 May 22; 58:60-67. PMID: 31128446.
      View in: PubMed
    4. Spidale NA, Sylvia K, Narayan K, Miu B, Frascoli M, Melichar HJ, Zhihao W, Kisielow J, Palin A, Serwold T, Love P, Kobayashi M, Yoshimoto M, Jain N, Kang J. Interleukin-17 Producing ?d T Cells Originate from SOX13+ Progenitors that Are Independent of ?dTCR Signaling. Immunity. 2018 Nov 06. PMID: 30413363.
      View in: PubMed
    5. Malhotra N, Qi Y, Spidale NA, Frascoli M, Miu B, Cho O, Sylvia K, Kang J. SOX4 controls invariant NKT cell differentiation by tuning TCR signaling. J Exp Med. 2018 Oct 04. PMID: 30287480.
      View in: PubMed
    6. Frascoli M, Coniglio L, Witt R, Jeanty C, Fleck-Derderian S, Myers DE, Lee TH, Keating S, Busch MP, Norris PJ, Tang Q, Cruz G, Barcellos LF, Gomez-Lopez N, Romero R, MacKenzie TC. Alloreactive fetal T cells promote uterine contractility in preterm labor via IFN-? and TNF-a. Sci Transl Med. 2018 Apr 25; 10(438). PMID: 29695455.
      View in: PubMed
    7. Falanga YT, Frascoli M, Kaymaz Y, Forconi C, Ong'echa JM, Bailey JA, Berg LJ, Moormann AM. High pathogen burden in childhood promotes the development of unconventional innate-like CD8+ T cells. JCI Insight. 2017 Aug 03; 2(15). PMID: 28768916.
      View in: PubMed
    8. Gomez-Lopez N, Romero R, Xu Y, Miller D, Unkel R, C MacKenzie T, Frascoli M, Hassan SS. Umbilical cord CD71+ erythroid cells are reduced in neonates born to women in spontaneous preterm labor. Am J Reprod Immunol. 2016 Oct; 76(4):280-4. PMID: 27625200.
      View in: PubMed
    9. Frascoli M, Jeanty C, Fleck S, Moradi PW, Keating S, Mattis AN, Tang Q, MacKenzie TC. Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5. J Immunol. 2016 Jun 15; 196(12):4957-66. PMID: 27183609.
      View in: PubMed
    10. Frascoli M, Proietti M, Grassi F. Phenotypic analysis and isolation of murine hematopoietic stem cells and lineage-committed progenitors. J Vis Exp. 2012; (65). PMID: 22805770.
      View in: PubMed
    11. Frascoli M, Marcandalli J, Schenk U, Grassi F. Purinergic P2X7 receptor drives T cell lineage choice and shapes peripheral ?d cells. J Immunol. 2012 Jul 1; 189(1):174-80. PMID: 22649196.
      View in: PubMed
    12. Schenk U, Frascoli M, Proietti M, Geffers R, Traggiai E, Buer J, Ricordi C, Westendorf AM, Grassi F. ATP inhibits the generation and function of regulatory T cells through the activation of purinergic P2X receptors. Sci Signal. 2011; 4(162):ra12. PMID: 21364186.
      View in: PubMed
    13. Casati A, Frascoli M, Traggiai E, Proietti M, Schenk U, Grassi F. Cell-autonomous regulation of hematopoietic stem cell cycling activity by ATP. Cell Death Differ. 2011 Mar; 18(3):396-404. PMID: 20798687.
      View in: PubMed
    14. Traggiai E, Casati A, Frascoli M, Porcellini S, Ponzoni M, Sanvito F, Leng L, Bucala R, Moretta L, Grassi F. Selective preservation of bone marrow mature recirculating but not marginal zone B cells in murine models of chronic inflammation. PLoS One. 2010; 5(6):e11262. PMID: 20582316.
      View in: PubMed
    15. Badi I, Cinquetti R, Frascoli M, Parolini C, Chiesa G, Taramelli R, Acquati F. Intracellular ANKRD1 protein levels are regulated by 26S proteasome-mediated degradation. FEBS Lett. 2009 Aug 6; 583(15):2486-92. PMID: 19589340.
      View in: PubMed
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