Sudhir Agrawal MSc, DPhil
| Title | Professor |
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| Institution | UMass Chan Medical School |
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| Department | Medicine |
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| Address | UMass Chan Medical School
364 Plantation Street
Worcester MA 01605
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| Phone | 857-998-8027 |
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| vCard | Download vCard |
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| Institution | T.H. Chan School of Medicine |
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| Department | Medicine |
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| Division | Infectious Diseases And Immunology |
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Biography
| University of Allahabad, Allahabad, UP, India | BS | | Chem, Botany, Zoology |
| University of Allahabad, Allahabad, UP, India | MS | | Science |
| University of Allahabad, Allahabad, UP, India | DPHIL | | Chemistry |
| MRC Laboratory of Molecular Biology, Cambridge, UK | Post Doctoral | | Nucleic Acids |
| University of Massachusetts Medical School, Worcester, MA | Foundation Scholar | | Antisense |
Overview
Over three decades, three drug-discovery platforms have been introduced in my laboratory based on synthetic oligonucleotides. These include: Antisense technology, Toll-Like Receptor Agonism, and Toll-Like Receptor Antagonism. Drug candidates from these technologies have been created and have advanced to clinical proof of concept trials in patients. These technologies have also been licensed to biotechnology and pharmaceutical companies. Several drugs have been approved based on ASO chemistry licensed from Idera.
Publications available on Google Scholar
Bibliographic
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication.
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Agrawal S. The Evolution of Antisense Oligonucleotide Chemistry-A Personal Journey. Biomedicines. 2021 May 03; 9(5).
PMID: 34063675.
Citations:
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Agrawal S. RNA Therapeutics Are Stepping Out of the Maze. Trends Mol Med. 2020 12; 26(12):1061-1064.
PMID: 32988738.
Citations:
3 Fields:
Translation:
Humans
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Agrawal S, Kandimalla ER. Role of Toll-like receptors in antisense and siRNA [corrected]. Nat Biotechnol. 2004 Dec; 22(12):1533-7.
PMID: 15583662.
Citations:
42 Fields:
Translation:
Humans
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Agrawal S, Kandimalla ER. Medicinal chemistry and therapeutic potential of CpG DNA. Trends Mol Med. 2002 Mar; 8(3):114-21.
PMID: 11879771.
Citations:
12 Fields:
Translation:
HumansAnimalsCells
This graph shows the total number of publications by year. To see the data as text,
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| Year | Publications |
|---|
| 2002 | 1 |
| 2004 | 1 |
| 2020 | 1 |
| 2021 | 1 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text,
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This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text,
click here.
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